Readable research linked to original sources
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Browse normalized, publication-ready research with direct links to its evidence and source.
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Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
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Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
135 articles
Newest firstSubstance use runs in families. Beyond genetic transmission, parental genetics can indirectly influence offspring substance use through the rearing environment, known as genetic nurture. This study utilizes transmitted and non-transmitted polygenic scores to investigate genetic nurture on tobacco, alcohol, and cannabis use in up to 15,863 adults with at least one genotyped parent from Lifelines, a population-based…
Open article record in new tab ↗PurposeThis study examined perceptions of a proposed US menthol cigarette ban among adults who smoke menthol cigarettes.DesignFocus group discussions.SettingVirtual focus groups with 7-9 participants each.Participants50 US adults (age 21+) who currently smoke menthol cigarettes participated in six focus groups: two with Black participants; two lesbian, gay, or bisexual participants; and two general population grou…
BACKGROUND: The use of stimulants, such as crack-cocaine, is a global public health concern. Crack-cocaine use is increasing in the UK, but available data is focused on those who inject or also use opioids. To address this gap, characteristics of people using crack-cocaine in England, including respiratory problems among those who smoke, and variation in these by gender are described. METHODS: Adults self-reportin…
Background Asian American, Native Hawaiian, and Pacific Islander (AANHPI) populations have diverse cultural, immigration, and sociodemographic characteristics. Aggregated data could mask substantial differences in substance use between cultural subgroups in this population. Yet, studies examining substance use among the AANHPI population are limited. Objective This study aimed to describe cigarette, cannabis, and…
Tobacco and cannabis use are prevalent among adults with HIV and co-use is associated with drug dependence and negative health outcomes such as lung disease. This study examined the co-use of tobacco and cannabis by HIV status overall and by sociodemographics. Data came from the adult sample from the 2021-2023 National Survey on Drug Use and Health. Adjusted multinomial logistic regressions were performed on tobac…
Open article record in new tab ↗Abstract Background: Substance use can negatively impact treatment adherence and health outcomes, thus exacerbating the burden of the disease. This study determined the prevalence and factors associated with substance use among patients with TB disease in Kampala, Uganda. Methods: This was a cross-sectional study of 144 patients with drug-susceptible TB enrolled from July 2020 to March 2021 across five health faci…
Open article record in new tab ↗Background Smoking is a leading cause of carcinogenesis in the head and neck region, representing a critical public health issue. Identifying genotoxic damage in smokers can provide valuable insights for developing preventive interventions. Aim To assess genotoxic damage through the micronucleus assay in exfoliated buccal mucosa cells from users of conventional tobacco, reverse smoking, cannabis, electronic cigare…
Open article record in new tab ↗Objective Characterize symptoms observed among people using nicotine and/or cannabis compared to non-users using an institutional respiratory illness symptom checker. Methods Cross-sectional study (April 2020-August 2021) using University of California San Francisco (UCSF) COVID-19 & Flu Symptom Checker online self-triage tool measuring current tobacco and cannabis use, symptom prevalence and associations with sel…
Open article record in new tab ↗Background and hypothesis Psychotic disorders (PDs) have huge personal and societal impact, and efforts to improve outcomes in patients are continuously needed. Environmental risk factors (ERFs), especially modifiable risk factors, are important to study because they pose a target for intervention and prevention. No studies have investigated ERFs, cognition, and psychotic symptoms together in a network approach. S…
Background Tobacco smoking is highly prevalent in patients with psychosis, who also often experience negative affect (NA) and stress. The relationship between these factors remains unclear in this population. We aimed to investigate everyday life associations in 158 patients with psychosis, 136 unaffected siblings, and 117 controls from the Genetic Risk and Outcome of Psychosis (GROUP) study with Experience Sampli…
Spontaneous pneumomediastinum (SPM) is defined as the presence of free air within the mediastinum without an apparent precipitating cause such as trauma, invasive procedures, or oesophageal rupture. SPM is typically benign and self-limiting but may mimic life-threatening conditions such as myocardial infarction, pulmonary embolism, or aortic dissection. The pathophysiology is most explained by the Macklin effect,…
Open article record in new tab ↗Background Although rates of tobacco use in California have declined overall, adults in the San Joaquin Valley (SJV), particularly Hispanic or Latinos ("Latinos"), have disproportionately high rates of tobacco use, tobacco-related illness, and mortality. Residents of the SJV also have limited access to cessation support services and need accessible, nonclinical alternatives. Given high smartphone use rates among L…
Background and Objectives: The impact of lifestyle on lower urinary tract symptoms has been deeply evaluated in recent years; however, studies in the young population are missing. The aim of this study is to evaluate the impact of alcohol intake, tobacco and cannabinoid smoking, physical activity, and dietary regime on urinary symptoms and sexual function in young adults under 30 years of age. Methods: A prospecti…
Open article record in new tab ↗Evidence suggests that diabetic smokers are less likely to quit smoking when compared to non-diabetic smokers. This study aimed to determine predictors of abstinence among diabetic smokers attending smoking cessation services (SCSs) across France. We analysed data from 94,827 adult smokers registered in the French national smoking cessation registry (CDTnet) between 2007 and 2016. Participants attended ≥2 SCS visi…
Open article record in new tab ↗Substance use (SU) and physical activity (PA) among university students changed with the beginning of the COVID-19 pandemic. In this study, we examined factors associated with SU and PA and profiles of these health behaviours in university students in Germany 20 months into the pandemic. A cross-sectional study on student well-being during the COVID 19-pandemic was conducted in October/November 2021 at five German…
Background The impact of multiple substance use on the risk of pancreatitis remains underexplored. Objective To systematically review peer-reviewed observational studies assessing the association of multiple substance use with the risk of acute pancreatitis (AP) or chronic pancreatitis (CP) in adults. Design We conducted a systematic review informed by the Preferred Reporting Items for Systematic Review and Meta-A…
Open article record in new tab ↗Background and aims E-cigarettes can aid smoking cessation and reduce carcinogen exposure. Understanding differences in characteristics between young adults who quit smoking, with or without e-cigarettes, or dual use can help tailor interventions. The aim of this study was to describe first transitions from smoking and explore substance use, sociodemographic, and health characteristic associations with the probabi…
Purpose of review Infertility affects approximately 15% of couples, with male factors implicated in more than 50% of cases. Concerns over declining semen quality - evidenced by a more than 50% drop in sperm concentration over four decades - have triggered investigation into modifiable lifestyle and environmental factors. This review summarizes recent evidence on exposures that negatively impact male fertility. Rec…
Open article record in new tab ↗BackgroundParental smoking increases offspring smoking risk. Young people with mental health difficulties are more likely to have parents who smoke and start smoking themselves. Improving mental health in youth could help disrupt intergenerational cycles of nicotine use, but the extent to which depressive symptoms mediate the link between parental and offspring smoking remains unclear. MethodsWe used data on 6,729…
Open article record in new tab ↗BackgroundAortic aneurysm (AA) is a life-threatening disease with significant global burden. ObjectivesThis study aims to evaluate epidemiological trends and risk factors for AA-related mortality from 1990 to 2021 across regions, accounting for age, sex, and socio-economic factors. MethodsUsing Global Burden of Disease (GBD) Study 2021, we analyzed AA-related death, death rates, and the age-standardized AA-related…