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Browse normalized, publication-ready research with direct links to its evidence and source.
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Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
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Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
477 articles
Newest firstCannabis use can have detrimental effects on adolescents' mental health, often co-occurring with child and adolescent psychiatric disorders (CAPD). This study assessed diagnostic prevalence trends in cannabis-related disorders and co-occurring diagnosed CAPD in adolescents receiving outpatient treatment in Germany. Outpatient claims data from the national public health insurance system, covering almost 4 million c…
Open article record in new tab ↗Introduction The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), continues to pose major health challenges despite effective vaccination efforts. The sustained occurrence of breakthrough infections and emerging variants of the virus highlights the need for additional therapeutic strategies. Given the anti-inflammatory role of the cannabinoid typ…
Introduction The COVID-19 pandemic was associated with high levels of depression and anxiety among pregnant individuals in the UK, as shown previously in the EPPOCH cohort. However, the relationships between these psychological burdens, pandemic-related stressors, and substance use in the prenatal period have not been systematically investigated. Methods To address this gap, we conducted a cross-sectional analysis…
BACKGROUND: COVID-19 caused disruptions in access to oncology health care for patients with breast cancer. This study explored the time differences in days from the initial patient call to time-to-treatment initiation (TTI) and evaluated the relationship between initial in-person consult (IPC) and telehealth consult (THC). METHODS: Retrospective data were collected for the years 2019, 2020, and 2021. Demographic c…
Open article record in new tab ↗PURPOSE OF REVIEW: This review aims to collate takeaways from the most recent and relevant literature related to tics, from genetic studies to case studies elucidating Functional tic like behaviors (FTLBs) and clinical trials of novel drugs in development. RECENT FINDINGS: Recent genome-wide association studies (GWAS) and functional neuroimaging studies have enhanced the understanding of genetic and structural lin…
Open article record in new tab ↗Background The COVID-19 pandemic disproportionately affected certain populations, with intimate partner violence (IPV) survivors facing heightened risks of adverse health outcomes. This study examined whether women who experienced IPV during Ontario's COVID-19 lockdowns were more likely to report negative behavioural, psychological, and physiological health outcomes compared to women who did not experience IPV . M…
Background The COVID-19 pandemic disrupted face-to-face alcohol and other drug (AOD) treatment services and prompted greater use of telehealth. This study measured the impact of COVID-19 on outpatient treatment episodes before, during, and after stay-at-home orders were introduced. Methods This observational study used routinely collected data from community-based non-government AOD services in New South Wales (NS…
Introduction This study quantifies excess mortality in Spain during and after the COVID-19 pandemic and assesses whether mortality levels are returning to pre-pandemic patterns. Methods Expected mortality was estimated using stochastic forecasting models calibrated on pre-pandemic data (1990-2019) and compared with observed mortality over the period 2020-2023. The analysis relies on a multi-model framework includi…
Open article record in new tab ↗Ethnic minority and migrant populations experienced disproportionately severe COVID-19 outcomes across Europe, yet the mechanisms underlying these disparities, particularly inequities in healthcare access, remain insufficiently understood at the patient level. This qualitative study examines healthcare-seeking behaviours and access to care among ethnically diverse patients hospitalised with COVID-19 in Amsterdam b…
Open article record in new tab ↗IntroductionThe coronavirus disease 2019 (COVID-19) pandemic has challenged health care systems worldwide, in certain areas exceeding hospital capacities and human resources. This has underscored the importance of having better tools to predict the outcome of potentially severe respiratory infections such as SARS-CoV-2. Predicting COVID-19 severity may allow physicians to better manage ICU beds and increase the ch…
Open article record in new tab ↗BackgroundThe global SARS-CoV-2 pandemic disrupted healthcare systems worldwide, raising concerns about its impact on clinical research. Early reports suggested reductions in participant enrollment, interruptions to ongoing trials, and challenges to protocol adherence, yet the magnitude and duration of these operational disruptions remain unclear. MethodsWe conducted a registry-based analysis comparing clinical tr…
Open article record in new tab ↗AimsCOVID-19 and influenza continue to impose a substantial burden on the Canadian healthcare system, particularly among adults aged [≥]65 years. This study compared the clinical and economic outcomes of a "Stand-alone" vaccination strategy with separate influenza and COVID-19 vaccines versus a "Combination" strategy incorporating mRNA-1083, an investigational vaccine targeting both infections. MethodsThe study ad…
Open article record in new tab ↗BackgroundHigh-demand sanitary crises, such as the COVID-19 pandemic, impose a high burden on healthcare professionals, increasing their risk of burnout. Healthcare postgraduate (HCP) trainees compound the general healthcare professional workforce and may face unique risks and challenges. This study aimed to evaluate the incidence of burnout and identify its predictors among healthcare postgraduate trainees during…
BackgroundNon-communicable diseases (NCDs) are significant public health concerns in Bangladesh, placing a heavy burden on the healthcare system. While the situation before COVID-19 was well-documented, it is unclear how the pandemic has impacted the prevalence and risk factors of these diseases. This study provides the first comparative assessment of the prevalence and determinants of diabetes mellitus (DM) and h…
Open article record in new tab ↗BackgroundThe COVID-19 pandemic significantly disrupted healthcare services globally, particularly in low-resource settings. This study explores the impact of the pandemic on physiotherapy services in Nepal. MethodsA cross-sectional study was conducted. Qualitative data were collected through semi-structured interviews with 12 physiotherapists, while quantitative data were gathered from an onsite survey of 29 heal…
Nurses represent the largest segment of the United States healthcare workforce and played an instrumental role in the countrys response to the COVID-19 pandemic. Yet, little attention has been given to the contribution of this component of the U.S. medical personnel in the nations ability to face public health crisis. We present a cross-sectional, ecological analysis using cumulative annual reports from different…
Open article record in new tab ↗SARS-CoV-2 strained Ontarios health system, with social determinants of health (SDH) underexplored in cost analyses. We examined COVID-19 attributable healthcare resource use and costs from the Ontario health system perspective using health administrative data. We conducted a cohort study, matching 162,633 SARS-CoV-2-exposed individuals 1:1 to unexposed individuals. We calculated 10-day per-person mean attributabl…
Open article record in new tab ↗BackgroundDuring the COVID-19 pandemic period, healthcare systems substantially reorganized their management of several diseases, including acute cardiovascular diseases (ACVD) such as heart failure, stroke, myocardial infarction, and pulmonary embolism. While previous studies have reported changes in hospitalization rates and clinical outcomes, the economic impact of the pandemic on healthcare expenditures for pa…
Adolescence is a developmental period characterised by increased vulnerability to cannabis use disorder (CUD). However, previous investigations of this vulnerability have relied on cross-sectional comparisons and lack a detailed assessment of cannabis quantity, a potentially important confounding factor. Here, we aimed to investigate the one-year course of CUD in adolescents compared to adults who currently use ca…