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Browse normalized, publication-ready research with direct links to its evidence and source.
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Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
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Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
37 articles
Newest firstDiabetes mellitus is an increasing public health challenge in Uganda and other low- and middle-income countries, where health systems face growing demands for chronic disease care. Although quantitative studies have documented poor glycemic control and health system constraints, less is known about how patients and healthcare providers experience diabetes management in peri-urban public health settings. This study…
Open article record in new tab ↗ObjectiveTo determine the absolute risk of starting dialysis versus mortality among adults with chronic kidney disease (CKD) treated at EsSalud from 2013 to 2022, utilizing data from the Renal Health Surveillance system (VISARE). MethodsThis retrospective cohort study analyzed clinical records from the VISARE system (EsSalud). We estimated rates of dialysis initiation and death using Fine & Gray competitive risk m…
BackgroundPoor glycemic control, a contributor to the development of diabetes related complications among patients with diabetes mellitus, remains a public health challenge in low-and middle-income countries. In Uganda, limited evidence exists on predictors of poor glycemic control among diabetic patients attending peri-urban primary healthcare facilities. The study assessed predictors of poor glycemic control amo…
BackgroundNon-communicable diseases (NCDs) are significant public health concerns in Bangladesh, placing a heavy burden on the healthcare system. While the situation before COVID-19 was well-documented, it is unclear how the pandemic has impacted the prevalence and risk factors of these diseases. This study provides the first comparative assessment of the prevalence and determinants of diabetes mellitus (DM) and h…
Open article record in new tab ↗Background/Objectives: Diabetes mellitus is a growing global health concern, driving the exploration of new therapies like cannabidiol (CBD), which shows potential in improving insulin sensitivity and glycemic control, though its effects on glucose metabolism remain unclear. This study evaluates CBD's dose-dependent effects on glycemia, insulin, and hepatic carbohydrate metabolism in diabetic rats. Methods: The Or…
Open article record in new tab ↗This study reviews the anti-inflammatory potential of cannabidiol (CBD) in the management of type 1 diabetes (T1D). A comprehensive search was conducted across PubMed, Scopus, and ScienceDirect databases using the terms "type 1 diabetes", "cannabidiol", "anti-inflammatory effect", and "CBD". Articles published between 2005 and 2025 were screened, and studies involving animal models that examined CBD as a therapeut…
Evidence suggests that diabetic smokers are less likely to quit smoking when compared to non-diabetic smokers. This study aimed to determine predictors of abstinence among diabetic smokers attending smoking cessation services (SCSs) across France. We analysed data from 94,827 adult smokers registered in the French national smoking cessation registry (CDTnet) between 2007 and 2016. Participants attended ≥2 SCS visi…
Open article record in new tab ↗Diabetes is a chronic metabolic disease that is widespread and has negative consequences for health and well-being. Substance use disorder (SUD) is characterized by the uncontrolled use of substances, including tobacco, alcohol, marijuana, and illicit drugs, leading to impaired mental and physical health. Individuals with coexisting diabetes and SUD experience exacerbated consequences, including increased suscepti…
BackgroundDiabetic foot complications are a leading cause of morbidity, disability, and healthcare costs worldwide, yet they are largely preventable through proper self-care. In Palestine, evidence on patient adherence to recommended practices is scarce. This study aimed to assess the knowledge, attitudes, and practices of foot self-care among adults with diabetes in the West Bank and to identify factors associate…
BackgroundDiabetes represents an emerging global health crisis, with lower-middle-income countries experiencing a fast growth in prevalence. Diabetes care in these regions often faces significant challenges, including inadequate healthcare infrastructure, limited financial resources, a shortage of trained healthcare personnel, and a dual burden of communicable and non-communicable diseases. Artificial intelligence…
Open article record in new tab ↗BackgroundDiabetes mellitus can increase hospitalization time, requiring a multidisciplinary team and specific, high-cost supplies. In this context, the study aimed to analyze the total costs, including hospital services and professional services, of hospitalizations of patients with diabetes mellitus in Brazil between 2013 and 2023. MethodsThis is a time series study developed using secondary data collected from…
Open article record in new tab ↗IntroductionDiabetes mellitus (DM) in Bahia, Brazil, is a critical public health issue, intensified by socioeconomic inequalities. Years of life lost (YLL) highlight healthcare access gaps, impacting vulnerable populations. Enhanced healthcare infrastructure, education, and policy changes are essential to reduce DM morbidity and premature mortality. ObjectiveTo quantify the societal burden of DM in Bahia, Brazil,…
Open article record in new tab ↗Clinical and experimental studies have demonstrated that type 2 diabetes mellitus (T2DM) affects the brain structure and function, in particular the hippocampus, leading to cognitive impairments. However, the molecular mechanisms underlying cognitive deficits induced by T2DM are not fully understood. In this study, we aimed to investigate the effects of T2DM on behavior, the proteome profile in the hippocampus, an…
Open article record in new tab ↗Patients with psychotic disorders exhibit elevated mortality and morbidity rates compared to the general population primarily due to comorbid somatic diseases. This study aims to describe the prevalence of selected risk factors and somatic disorders among psychiatric patients with a diagnosis of psychotic disorder. Material and methods: Data were retrieved from Greenland's nationwide electronic medical record. The…
Background The comorbidity between diabetes mellitus and depression was revealed, and diabetes mellitus increased the prevalence of depressive disorder, which ranked 13th in the leading causes of disability-adjusted life-years. Insulin resistance, which is common in diabetes mellitus, has increased the risk of depressive symptoms in both humans and animals. However, the mechanisms behind the comorbidity are multi-…
ObjectiveDiabetes mellitus poses significant challenges to individuals well-being, affecting various aspects of their lives beyond the physical symptoms of the disease. Understanding the multidimensional aspects of QoL among diabetic patients is crucial for providing holistic healthcare interventions and improving overall health outcomes. The study aims to evaluate the quality of life of Type II Diabetes Mellitus…
Open article record in new tab ↗PurposeThe open, prospective Community-Based chronic Care Lesotho (ComBaCaL) cohort is the first study to comprehensively investigate socioeconomic indicators, common chronic diseases and their risk factors in a remote rural setting in Lesotho. It serves as a platform for implementing nested trials using the Trials within Cohorts (TwiCs) design to assess community-based chronic care interventions. Here, we present…
Introduction and AimDiabetes is a global health emergency with increasing prevalence and diabetes-associated morbidity and mortality. One of the challenges in optimising diabetes care is translating research advances in this heterogenous disease into clinical care. A potential solution is the introduction of precision medicine approaches into diabetes care. We aim to develop a digital platform called intelligent D…
BackgroundThe World Health Organization has designed a package of essential non-communicable diseases (PEN) strategy to improve the detection and management of NCDs. However, the implementation of the PEN in Ethiopia is at an early stage and the readiness of rural primary healthcare units (PHCUs) to implement the strategy is unknown. We, therefore, propose to apply the strategy in the catchment areas of Dobe-Toga…
BackgroundIntegrating Tuberculosis (TB), Diabetes Mellitus (DM), and Tobacco-Control (TC) programs in India presents a promising strategy to address the triple burden of these diseases. However, limited information exists regarding the feasibility and influencing factors of such integration. This study investigates potential barriers and facilitators to integrate TB, DM, and TC programs in Ambegaon Block of Pune D…