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Browse normalized, publication-ready research with direct links to its evidence and source.
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Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
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Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
50 articles
Newest firstBackground Gender identity influences patterns of substance use; however, few population-level studies have included transgender and gender-diverse identities when examining patterns of cannabis use by gender identity. Methods Data are from the International Cannabis Policy Study's national, repeat cross-sectional surveys conducted annually between 2018-2023 in Canada and the United States. Weighted logistic and l…
Open article record in new tab ↗BACKGROUND: The use of stimulants, such as crack-cocaine, is a global public health concern. Crack-cocaine use is increasing in the UK, but available data is focused on those who inject or also use opioids. To address this gap, characteristics of people using crack-cocaine in England, including respiratory problems among those who smoke, and variation in these by gender are described. METHODS: Adults self-reportin…
BackgroundThis study compared prevalence of youth substance use by gender and type of chronic health condition (CHC); estimated gender-stratified odds of substance use across CHCs; and, contrasted effect sizes across CHCs and genders.MethodsData come from 13,580 youth 12 to 17 years in the 2019 Canadian Health Survey on Children and Youth (48.7% girls). CHC was categorized as none (38.4%), physical only (39.8%), m…
The large yellow croaker (Larimichthys crocea) is an economically important marine fish in China, whose growth rate in aquaculture has yet to meet the industry's demands. Understanding the mechanism underlying inter-individual growth differences will create a favorable condition for selective breeding. In combined transcriptome and metabolome analyses, this study collected muscle tissues from four groups of croake…
Background There is a growing body of evidence on health inequalities according to gender identity, in which sex assigned at birth is often overlooked. The aim of our study was to assess the relevance of examining both gender identity and sex assigned at birth in health population surveys, by comparing the health outcomes, behaviours, and interpersonal relationships in cisgender boys, cisgender girls, transgender…
Background Several studies have reported associations between attention-deficit/hyperactivity disorder (ADHD) and substance use disorders (SUD). However, sex-differences in ADHD and SUD, especially when associated with other psychiatric comorbidities, are less studied. Objective To compare the prevalence of SUD among individuals with and without ADHD to describe groups, defined by sex and psychiatric comorbidity,…
Harm reduction (HR) services are developing in Africa. In Senegal, the overall HR service coverage ratio is one WUD for every 10 men. By analysing gender-specific initiatives developed by HR stakeholders and evaluating their limitations, we explored HR in Senegal through a gender lens to better understand how to meet the specific needs of WWUD. The data for this study were collected through interviews, observation…
Open article record in new tab ↗Objective To assess heterogeneity in marijuana use among adolescent Asian American and Pacific Islander (AAPI) subgroups. Methods AAPI high school students (n = 31,071) participating in the 2019-2020 California Student Tobacco Survey were categorized by race/ethnicity and examined for ever and current (past-30-day) marijuana use. Descriptive statistics were used to describe marijuana use and harm perceptions by su…
Open article record in new tab ↗IntroductionCannabis use and cannabis use disorder (CUD) are more prevalent among men and boys than among women and girls. However, this sex/gender gap has been narrowing in recent decades, likely due to an increase in cannabis use among women and girls, who have been historically under-represented in cannabis research. The lack of sex- and gender-based approaches within cannabis research has been highlighted in p…
Open article record in new tab ↗Representation bias in health data can lead to unfair decisions and compromise the generalisability of research findings. As a consequence, underrepresented subpopulations, such as those from specific ethnic backgrounds or genders, do not benefit equally from clinical discoveries. Several approaches have been developed to mitigate representation bias, ranging from simple resampling methods, such as SMOTE, to recen…
Clinical decision instruments (CDIs) face an equity dilemma. On the one hand, they often reduce disparities in patient care through data-driven standardization of best practices. On the other hand, this standardization may itself inadvertently perpetuate bias and inequality within healthcare systems. Here, we quantify different measures of potential for implicit bias present in CDI development that can inform futu…
Open article record in new tab ↗Introduction While sexual assault may have particularly adverse emotional effects compared with other forms of trauma, it remains unclear which emotional outcome dimensions are impacted, whether cannabis outcomes are similarly impacted, and whether gender differences exist in sexual assault's links with these outcomes. Methods N = 100 cannabis users with trauma histories (M age = 33.1) completed standardized measu…
Objectives: This study assessed potential differences between girls and boys in the prevalence rates of cannabis use, sociodemographic factors, and beliefs about cannabis use. Methods: 1,896 Andalusian adolescents aged 14-18 participated in an online survey based on the I-Change model. The survey assessed their beliefs about cannabis use, including attitudes, social influences, self-efficacy, action planning, and…
Open article record in new tab ↗Background Substance use is a global health concern and early onset among adolescents increases health risks. We explore national overall trends in prevalence and trends in socioeconomic inequalities in past year alcohol intoxication, cannabis use, and use of other illicit drugs among Norwegian adolescents (ages ∼ 15-19 years of age) between 2014 and 2022. Method The present study builds on data from a nationwide…
Open article record in new tab ↗RationaleRecent reports have shown increased cannabis use among women, leading to growing concerns about cannabis use disorder (CUD). Some evidence suggests a faster progression to addiction in women, known as the "telescoping effect." While there is preclinical evidence suggesting biological sex influences cannabinoid effects, human research remains scant. We investigated sex differences in the response to oral t…
Legalization of cannabis use for non-medical (recreational) purposes is changing the global cannabis landscape. As attitudes toward cannabis use become more positive and prevalence of use increases in complex ways, concerns emerge about the potential for increased cannabis-attributable harms. Understanding the who, why, and when of this likely increase in cannabis-attributable harms is thus an important public hea…
Open article record in new tab ↗WIN55, 212-2 mesylate is a synthetic cannabinoid (SC) agonist of CB1 and CB2 receptors with much higher affinity to CB1 receptor than tetrahydrocannabinol and many potential therapeutic effects. Few studies have evaluated SCs effects on more complex animal behavior and sex differences in cannabinoids toxicology. The current study was undertaken for determination of behavioral (Open Field test), biochemical (liver…
Open article record in new tab ↗The co-occurrence of substance use disorders (SUD) and other mental disorders (OMD) is assumed to be high, but the details are uncertain in Spain. The objective of the present study was to know the prevalence of this comorbidity, as well as the pharmacological treatment, both in specific addiction treatment networks and in mental health networks, with a gender perspective. Observational, multicenter study, with a…
Open article record in new tab ↗Background Previous research suggests an increase in schizophrenia population attributable risk fraction (PARF) for cannabis use disorder (CUD). However, sex and age variations in CUD and schizophrenia suggest the importance of examining differences in PARFs in sex and age subgroups. Methods We conducted a nationwide Danish register-based cohort study including all individuals aged 16-49 at some point during 1972-…
Open article record in new tab ↗Background Medical cannabis has been legal in Canada since 2001, and recreational cannabis was legalized in October 2018, which has led to a widespread increase in the accessibility of cannabis products. Aims This study aimed to estimate the prevalence of cannabis use among adults living with chronic pain (CP) and investigate the relationship between age and cannabis use for CP management. Methods A cross-sectiona…