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Browse normalized, publication-ready research with direct links to its evidence and source.
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Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
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Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
21 articles
Newest firstObjectiveAs epidemiological patterns of cannabis use and internalizing problems evolve globally, it is critical to reassess their associations-particularly in the post-legalization and post-pandemic context.MethodsParticipants were assessed in the 2012 Canadian Community Health Survey's Mental Health Component (CCHS-MH; n = 25,113) and 2022 Mental Health and Access to Care Survey (MHACS; n = 9,861), two nationally…
Open article record in new tab ↗3,4-Methylenedioxymethamphetamine (MDMA) or "ecstasy," is a commonly used drug worldwide, including in New Zealand, where 4.8% of the population aged 15 years or over reported using it in a 2023/2024 survey. This study provides additional insights on MDMA prevalence data in New Zealand by reporting toxicology data from Coronial and driving under the influence of drugs (DUID) cases positive for MDMA between 2010 an…
Open article record in new tab ↗Accurate estimates of population drug use and an understanding of the factors that influence substance choice are essential for the development of appropriate and targeted prevention strategies and campaigns. This review aims to provide an overview of the socioeconomic and psychosocial factors that influence substance use patterns within the Australian population through exploration of current and historical examp…
Open article record in new tab ↗Background Cannabis use has increased among young individuals in recent years. Although dependent cannabis use disorder (CUD) has been associated with various cardiac events, its effects on young adults without concurrent substance use remain understudied. Aim To examine trends in hospitalizations for major adverse cardiac and cerebrovascular events (MACCE) in this cohort. Methods We used the National Inpatient Sa…
Across high-income countries, adolescent emotional concerns have been increasing in prevalence over the past two decades and it is unclear why this is occurring, including whether and how substance use relates to these changing trends. On the other hand, substance use has been generally declining, and little is known about the role of emotional concerns in these trends. Several studies have explored the changes in…
Open article record in new tab ↗BackgroundParoxysmal tachycardia encompasses various heart rhythm disorders that cause rapid heart rates. Its episodic occurrence makes it difficult to identify and measure its prevalence and trends in the population. Additionally, there is limited data on disparities and trends in mortality due to paroxysmal tachycardia, which is essential for assessing current medical approaches and identifying at-risk populatio…
BackgroundAs the deadline for eliminating schistosomiasis approaches, more targeted and effective interventions should be proposed. We aimed to understand the burden among various gender, ages, countries, and continents and to analyze the trends in the burden of schistosomiasis from 1990 to 2041. MethodsThis study utilizes data from the Global Burden of Disease (GBD) 2021 to analyze the schistosomiasis burden tren…
Open article record in new tab ↗BackgroundNeonatal mortality is a significant challenge that affects babies within the first 28 days of life. The issue is particularly challenging for healthcare systems in developing countries, where interventions are required. Although there has been a decline in neonatal mortality worldwide, comprehensive data on the patterns of neonatal mortality and the contributing factors in rural regions of Ethiopia is la…
Open article record in new tab ↗Background Peptic ulcer disease (PUD) is frequently seen in patients with liver cirrhosis. However, current literature lacks data on PUD in non-alcoholic fatty liver disease (NAFLD) hospitalizations. Aim To identify trends and clinical outcomes of PUD in NAFLD hospitalizations in the United States. Methods The National Inpatient Sample was utilized to identify all adult (≥ 18 years old) NAFLD hospitalizations with…
The COVID-19 pandemic had a substantial impact on healthcare delivery, particularly in general practice. This study aimed to evaluate how dispensing of medications in primary care in Ireland changed following the COVID-19 pandemics onset compared to expected trends. This interrupted time series study used data on medications prescribed in general practice 2016-2022 to patient eligible for state health cover, appro…
Open article record in new tab ↗Background The prevalence of Crohn's disease (CD) and ulcerative colitis (UC) is on the rise worldwide. This rising prevalence is concerning as patients with CD and UC may frequently relapse leading to recurrent hospitalizations and increased healthcare utilization. Aim To identify trends and adverse outcomes for 30 d readmissions for CD and UC. Methods This was a retrospective, interrupted trends study involving…
Background Alcohol use disorder, high-risk drinking, and emergency visits for acute and chronic complications of alcohol use have been increasing in the USA recently. Approximately half of patients with alcohol use disorder experience alcohol withdrawal when they reduce or stop drinking. Though alcohol withdrawal is usually mild, 20% of patients experience more severe manifestations such as hallucinations, seizure…
Open article record in new tab ↗Lung cancer is the leading cause of global cancer incidence and mortality, accounting for an estimated 2 million diagnoses and 1.8 million deaths. Neoplasms of the lungs are the second most common cancer diagnosis in men and women (after prostate and breast cancer, respectively). With increasing access to tobacco and industrialization in developing nations, lung cancer incidence is rising globally. The average age…
Open article record in new tab ↗Background Alcoholic liver cirrhosis (ALC) is a chronic liver disease with varying disease severity. Readmissions of ALC are associated with poor outcomes. Aim To identify and assess trends of readmissions for ALC over an eight-year period. Methods This retrospective interrupted trend study analysed 30-d readmissions of ALC in the United States from 2010 to 2018 using the National Readmissions Database. Hospitaliz…
Open article record in new tab ↗Adolescents engage in multiple health risk behaviours that put them at risk of future chronic disease. By the time students graduate from secondary school, they may be engaging in behaviours that set them on a particular health trajectory. It is important to monitor the co-occurrence of health risk behaviours of cohorts of grade 12 students over time to highlight important areas for intervention. The purpose of th…
Open article record in new tab ↗Aims: To describe trends in cannabis use from 2010 to 2019 among Norwegian adolescents and relate these to individual- and municipal-level variables. Design: Data from nationwide repeated cross-sectional surveys collected in 2010-2013 (T1), 2014-2016 (T2), and 2017-2019 (T3) were used to describe secular trends in proportions of adolescent cannabis use. Setting: Cross-sectional surveys in 410 of the total 428 muni…
Open article record in new tab ↗Objective This study was designed to assess the epidemiological trends and outcomes associated with Hepatorenal Syndrome (HRS). Methods This retrospective interrupted trend study used the Nationwide Inpatient Sample (NIS) database for the years 2008, 2012, 2014, 20z16 and 2018 to identify adult (≥18 years) hospitalizations with a primary diagnosis of HRS. We determined epidemiological characteristics and trends fo…
Open article record in new tab ↗Background Adolescent mental ill-health is a growing concern. There is little understanding of changes over time in the associations between mental health and health-related behaviours and outcomes such as substance use, anti-social behaviour and obesity. We investigate whether the associations between different health-related outcomes in adolescence are changing over time in two recent cohorts of adolescents born…
Open article record in new tab ↗Background and objectives: Modern-day epidemiologic data on the risk and shifting landscape of occurrence of cardiovascular events in cannabis users remain inadequate and rather conflicting, especially amongst the young adult population. Furthermore, the problem of polysubstance use among youth is challenging for healthcare professionals and policy-makers. Previous studies report higher risk of concomitant use of…
BACKGROUND: Despite a decrease in driving under the influence of alcohol (DUIA) prevalence over the past decades, DUIA prevalence still remains high in the United States. To date, there is limited research examining whether different types of substance users have different trends in DUIA. This study sought to assess trends and variables associated with DUIA by substance use type. METHODS: National Survey on Drug U…
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