Readable research linked to original sources
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Browse normalized, publication-ready research with direct links to its evidence and source.
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Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
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Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
78 articles
Newest firstABSTRACTBackgroundResearch indicates that first‐episode psychosis (FEP) with cannabis use disorder (CUD) carries a substantial disease burden, but more granular clinical trajectories of cannabis‐related psychoses remain unclear. This study examines the clinical trajectories of first clinically diagnosed FEP&CUD and cannabis‐induced psychosis (CIP) in comparison with FEP without substance use disorder (SUD).Methods…
Open article record in new tab ↗BackgroundPopulation-level data on preclinical heart failure (HF) remain limited because most epidemiological studies focus on symptomatic HF. We therefore developed an administrative-data algorithm to classify HF stages across the national population and describe temporal trends, stage transitions, and mortality across the HF continuum. MethodsUsing a claims-based staging framework adapted from the Universal Defi…
Open article record in new tab ↗BackgroundThe U.S. has the highest health care expenditure globally. Examining long-term national and state-level trends, and benchmarking them against other health systems, can provide important insights for public health planning and policy development. AimThis study aimed to characterize temporal trends in the burden of bladder cancer, including prevalence, incidence, mortality, disability-adjusted life years (…
ObjectiveTo determine the absolute risk of starting dialysis versus mortality among adults with chronic kidney disease (CKD) treated at EsSalud from 2013 to 2022, utilizing data from the Renal Health Surveillance system (VISARE). MethodsThis retrospective cohort study analyzed clinical records from the VISARE system (EsSalud). We estimated rates of dialysis initiation and death using Fine & Gray competitive risk m…
BackgroundNursing workload in intensive care units (ICUs) plays a crucial role in determining patient outcomes, quality of care, and healthcare system efficiency. The Nursing Activities Score (NAS) is a validated tool used internationally to measure nursing workload and estimate the proportion of nursing time required for patient care. However, evidence regarding its application in low- and middle-income countries…
Open article record in new tab ↗Introduction We aimed to determine whether the trend in the rate of drug-induced hospitalisations and deaths changed during the first year of the COVID-19 pandemic in Australia. Methods Data comprised crude monthly rates (per 1,000,000 persons) of hospitalisations and deaths directly attributable to illicit drugs, prescription medicines, or medicines available without a prescription, nationally from 2011 to 2021.…
Open article record in new tab ↗Background Few studies have reported on the prevalence and health risks associated with substance use and substance use disorder (SU/SUD) in Veterans who use long-term opioid therapy (LTOT). We leveraged health record data to estimate SU/SUD prevalence and its association with mortality among Veterans on LTOT. Methods We conducted a secondary analysis of cohort data for Veterans on LTOT within Veterans Health Admi…
Open article record in new tab ↗Background Asthma, a chronic respiratory disease affecting over 300 million individuals globally, significantly impacts the quality of life and healthcare systems. In recent years, cannabis use disorder (CUD) has emerged as a potential complicating factor. Cannabis, though increasingly legalized and perceived as benign, poses risks to respiratory health. This study explores the relationship between CUD and asthma…
Open article record in new tab ↗BackgroundCoronavirus disease 2019 (COVID-19) has had a profound impact on cardiovascular health, influencing both the presentation and outcomes of acute myocardial infarction. This study aimed to evaluate the demographic and clinical profiles of patients with ST-segment elevation myocardial infarction (STEMI) presenting to a tertiary care center during the COVID-19 pandemic and to compare early and late presenter…
BackgroundMpox, a zoonotic disease endemic to Africa, presents a significant public health threat with variable severity driven by viral clades and host factors. After over 50 years of outbreaks, this study aimed at providing a comprehensive continent-wide assessment of its severity and mortality for evidence-based public health planning and clinical management. MethodsThis systematic review and meta-analysis, con…
Open article record in new tab ↗IntroductionMigrants are drawn to high-income countries (HICs) for employment, often in sectors deemed difficult, risky, and low paying. However, they experience more injuries and deaths and face barriers to healthcare. The World Health Organization has highlighted migrant health as a priority. While Hargreaves et al. and others studied migrant occupational health, most did not compare with residents. Lau et al. a…
Open article record in new tab ↗An estimated 1.9 million stillbirths and 2.3 million neonatal deaths occurred globally in 2023, disproportionately clustered in sub-Saharan Africa and South Asia. We aimed to determine the frequency of delays in illness recognition, healthcare seeking, and healthcare receipt among cases of stillbirth neonatal death, to characterize the most common delays, and to describe the frequency of antenatal care visits prec…
Open article record in new tab ↗BackgroundTraumatic brain injury (TBI) is a serious global health problem contributing significantly to disability and death. No systematic review existed on epidemiology of TBI in South Asia, where accurate data were essential for planning healthcare policy and injury prevention programs. MethodsThis systematic review adhered to PRISMA guideline and received registration from PROSPERO (CRD42022364511). This revie…
BackgroundSubstantial geographic disparities in cardiovascular disease (CVD) mortality persist across the United States. The extent to which "place" reflects underlying socioeconomic and behavioral risk factors remains insufficiently explained. This study applies machine learning to quantify the determinants of these disparities. MethodsA cross-sectional analysis linked county-level 2019-2020 age-adjusted CVD mort…
Open article record in new tab ↗BackgroundMpox, caused by the Mpox virus, is a zoonotic disease historically endemic in Central and West Africa. The Democratic Republic of Congo (DRC) bears the highest burden, with evolving epidemiology and significant public health challenges. Understanding severity and mortality trends is critical for global control efforts. MethodsThis systematic review and meta-analysis followed PRISMA guidelines to synthesi…
BackgroundPre-procedural risk prediction of 30-day all-cause mortality after percutaneous coronary intervention (PCI) aids in clinical decision-making and benchmarking hospital performance. This study aimed to identify pre-procedural factors to predict the risk of 30-day all-cause mortality post-PCI using machine learning (ML) approaches. MethodsThe study analysed 93,055 consecutive PCI procedures. Boruta feature…
Open article record in new tab ↗IntroductionChild mortality is a critical global health indicator, reflecting a nations development and healthcare quality. Despite significant progress in reducing child mortality globally, Somalia continues to experience high rates, particularly among infants and young children, due to preventable and treatable conditions. Malnutrition, birth complications, and infectious diseases are the leading causes of death…
Open article record in new tab ↗IntroductionHealthcare systems were reorganised in 2020 to manage the COVID-19 pandemic. Despite their urgent status, hospital admissions for acute heart failure (AHF) were reported to decline from 9% to 66% worldwide between 2020 and 2021, with divergent findings regarding in-hospital mortality. This study aimed to investigate in detail the evolution of AHF hospitalisations and in-hospital mortality in France fro…
Hospitals are increasingly adopting artificial intelligence (AI) tools in clinical care. However, their overall impact on the health of older adults remains unclear. We assessed whether county-level hospital AI implementation was associated with elder mortality and care quality using national data from the American Hospital Association (AHA), Centers for Medicare & Medicaid Services (CMS), and CDC WONDER. Higher A…
Open article record in new tab ↗The objective of this study is to analyze spatial distribution of mortality due to congenital syphilis in Brazil from 2008 to 2022. This is an ecological study that considered congenital syphilis deaths reported in all Brazilian municipalities, from 2008 to 2022, available in the Brazilian governments information systems. We built a thematic map to describe the distribution of congenital syphilis mortality in the…