Readable research linked to original sources
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Browse normalized, publication-ready research with direct links to its evidence and source.
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Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
Loading articles data…
Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
45 articles
Newest firstBackground In recent decades, the potency of cannabis resin increased globally, raising concerns, as higher potency has been associated with increased risk of psychiatric harms at the individual level. The aim here was to examine whether changes over time in the potency of seized cannabis resin samples were associated with psychiatric harms at the population level. Methods Data on ∆-9-tetrahydrocannabinol (THC) co…
Open article record in new tab ↗Background Cannabis use is increasing globally, with a parallel rise in Cannabis Use Disorder (CUD). Chronic pancreatitis (CP), a progressive inflammatory condition, is associated with acute pancreatitis (AP) flares and an elevated risk of pancreatic cancer (PC). Although cannabis is often used for pain management in CP, its impact on PC risk and AP flare frequency is unclear. Methods We conducted a retrospective…
BackgroundThe U.S. has the highest health care expenditure globally. Examining long-term national and state-level trends, and benchmarking them against other health systems, can provide important insights for public health planning and policy development. AimThis study aimed to characterize temporal trends in the burden of bladder cancer, including prevalence, incidence, mortality, disability-adjusted life years (…
BackgroundTyphoid fever incidence estimates are central to policy decisions on vaccine introduction and investments in non-vaccine prevention and control but are often unavailable. We explored whether prevalence metrics from sentinel studies of community-onset bloodstream infections could accurately predict local Salmonella Typhi (S. Typhi) incidence. MethodsUsing a previous systematic review (January 2018-Decembe…
Open article record in new tab ↗Background Drug use disorders (DUDs), a significant public health issue worldwide, encompass disorders related to sedatives, cannabis, opioids, heroin, hallucinogens, club drugs, and inhalants. This study examines the changes in the global burden of DUDs from 1990 to 2021, aiming to provide a scientific foundation for strategies to mitigate the harms associated with substance abuse. Methods The study utilized Glob…
Open article record in new tab ↗Drug use disorders (DUDs) represent a major global health challenge, leading to substantial morbidity and mortality, while also being compounded by social and structural barriers. In this study, we examined global epidemiological trends in DUDs over the past three decades to inform clinical and public health responses. We extracted data on the incidence, deaths, and disability-adjusted life years (DALYs) attributa…
Purpose The temporal trend of suicide in patients with cannabis use disorder (CUD) is important to investigate, considering the recent increases in THC concentration in cannabis products. This study describes the annual suicide rates in patients with CUD from 2010 to 2021. To investigate if any change in suicide rate was specific to CUD, we compared these suicide rates with corresponding data for patients with alc…
Background Alcohol-associated liver disease (ALD) is a leading cause of liver-related morbidity and mortality, yet effective therapeutic options remain limited. Preclinical data suggest that modulation of the hepatic endocannabinoid system, particularly via cannabidiol (CBD), may reduce alcohol-induced liver injury. Due to CBD's limited clinical use, we sought to evaluate the association between cannabis use and A…
Background: Kidney transplant recipients (KTRs) have an increased risk for cardiovascular disease (CVD) and cerebrovascular disease (CBD). This study investigated the risks of CVD and CBD following kidney transplantation. Materials and methods: This retrospective cohort study enrolled 3596 KTRs between 2003 and 2017. Propensity Score Matching (PSM) was performed to select patients without a kidney transplant, who…
Aim The environment shapes the risk of psychosis. In particular, urbanicity, deprivation or inequality, migrant density and cannabis availability may not only influence psychosis incidence, but also the characteristics of individuals who arrive at clinical services. This study examined how socioeconomic factors influence the incidence and characteristics of cases of First-Episode Psychosis (FEP). Methods We analys…
Background Congenital biliary dilatation (CBD) is a rare anomaly often treated surgically, yet postoperative complications remain a concern. This study aimed to evaluate the incidence, timing, and risk factors of such complications after CBD surgery. Methods A retrospective review was conducted on 184 patients with CBD who underwent either open or laparoscopic surgery, with a mean follow-up of 9 years. The analysi…
Melioidosis outbreaks in Taiwan frequently coincided with severe typhoons. Over a 20-year period, 782 cases of melioidosis were reported, with outbreaks often clustering in a specific hotspot area. We hypothesized that the unique hilly terrain in this hotspot trapped contaminated aerosols generated from northern to northwestern farming land within the area and restricted their spread beyond it. Across Taiwan, and…
Open article record in new tab ↗Objective Cannabis use disorder (CUD) is increasingly prevalent in the United States, yet long-term health consequences remain poorly defined. Oral cancer is plausible given shared carcinogens between cannabis and tobacco. This study assessed associations between CUD and five-year oral cancer risk in a large clinical cohort. Methods This retrospective cohort study analyzed clinical records from the University of C…
Open article record in new tab ↗Background and aims Ventricular tachycardia and ventricular fibrillation underlie many sudden cardiac deaths, but common lifestyle factors that predict their occurrence are poorly understood. This study aimed to assess the association between methamphetamine and cocaine, the most used illicit stimulants, and ventricular arrhythmias (VA) and mortality. Methods Healthcare databases were used to identify adults aged…
Aims/hypothesisTo investigate updated trends in the incidence and prevalence of diagnosed type 2 diabetes in Norway by age, sex, country of birth and education. MethodsA nationwide cohort study using registries on primary and specialist healthcare, dispensed drugs, and demographic factors in Norway. We analysed incidence trends 2009-2021 using Poisson regression and JoinPoint. ResultsDuring 2009-2021, 195 935 inci…
Open article record in new tab ↗Background Cannabinoid-based medicines (CBMs) are being used widely in older people. However, information on the incidence of adverse events (AEs) is limited. Objective To quantify the incidence rate difference (IRD) of AEs in middle aged and older adults of age ≥50 years receiving CBMs and also examine associations with weekly doses. Design Systematic review and meta-analysis. Data sources MEDLINE, PubMed, EMBASE…
In June 2022, Thailand legalized recreational cannabis. Currently, cannabis is now the most consumed drug. Cannabis usage can increase inflammatory responses in the respiratory tract. Sharing of cannabis waterpipes has been linked to increased tuberculosis risks. Using a national in-patient databank, we aimed to 1) describe the spatiotemporal correlation between cannabis-related and tuberculosis hospital admission…
Open article record in new tab ↗Little is understood about the unintended consequences of cannabis liberalization on children. Subsequently, this scoping review aimed to map and identify evidence related to acute cannabis intoxication in children. We searched three medical literature databases from inception until October 2019. We identified 4644 information sources and included 158 which were mapped by topic area relating to 1) public health im…
Open article record in new tab ↗Cannabis-related emergency department visits have increased after legalization of cannabis for medical and recreational use. Accordingly, the incidence of emergency department visits due to cannabinoid hyperemesis syndrome in patients with chronic cannabis use has also increased. The aim of this study was to examine trends of emergency department visit due to cannabinoid hyperemesis syndrome in Nevada and evaluate…
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