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Browse normalized, publication-ready research with direct links to its evidence and source.
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Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
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Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
156 articles
Newest firstIntroductionCannabis use has been linked to alterations in cognitive control and emotional processing, although findings vary according to use pattern and abstinence status. This pilot study examined whether emotional interference is especially sensitive to short-term abstinence-related differences across cannabis-use profiles and whether such differences are accompanied by distinct prefrontal hemodynamic response…
Open article record in new tab ↗Introduction and aims Cannabis use among university students is a growing concern, particularly in demanding medical programs. We estimated prevalence, identified predictors, and compared coping strategies among medical students in Uganda. Design and methods Cross-sectional survey of 318 undergraduates at Kampala International University (Western Campus). Cannabis use and hazardous/disordered use were screened wit…
Background Educational attainment (EA), which comprises cognitive (CogEA) and noncognitive (NonCogEA) components, is positively genetically correlated with alcohol and cannabis use but negatively correlated with alcohol and cannabis use disorders (AUD and CUD). These paradoxical associations suggest that shared genetic influences with EA may differ by level of substance involvement. Methods To test this, we examin…
Aim This study aimed to investigate the association between cannabis use prior to enrollment in a First Episode Psychosis (FEP) program and prognosis, including severity of psychiatric symptoms, type of antipsychotic treatment prescribed, and clinical recovery. Methods A longitudinal cohort study was conducted on patients aged 18-35 diagnosed with affective and non-affective psychosis who were referred to the FEP…
ABSTRACTBackground and AimsGiven the rising prevalence of cannabis use as an alternative strategy for managing mental health symptoms, there is a crucial need to understand the determinants of substitution behavior, particularly among midlife women who may experience distinct psychosocial and clinical profiles. This study examined the predictors of cannabis substitution among midlife women by comparing profiles of…
Open article record in new tab ↗Objective This study aimed to evaluate the accuracy, completeness, and clinical usefulness of YouTube (Alphabet Inc., Mountain View, CA) videos about cannabinoid hyperemesis syndrome (CHS). Methods This cross-sectional study assessed YouTube videos that were identified using standardized CHS-related search terms and predefined eligibility criteria. Trained reviewers used an author-developed CHS content checklist a…
Open article record in new tab ↗Background Romantic relationships are important contexts for substance use and emotional well-being. We tested the hypotheses that (i) genetic predispositions for alcohol consumption would be positively associated with partner substance use, (ii) partner substance use would moderate genetic influences on one's own alcohol outcomes, and (iii) partner discordance in substance use would be associated with lower emoti…
Cannabis use has increased significantly in recent years, yet its impact on local anesthetic efficacy in oral surgery remains poorly understood. This report analyzes the case of a 34-year-old male with history of chronic cannabis use who exhibited a hyperalgesic pain response and difficulty achieving adequate anesthesia during dental extraction in spite of standard anesthetic techniques. This atypical presentation…
Open article record in new tab ↗BACKGROUND: Cannabis use is becoming increasingly prevalent in the United States, and its implications extend into many facets of society, including healthcare. Despite legal and societal shifts toward the acceptance of cannabis, healthcare professionals face ethical and legal complexities related to cannabis use. Understanding perceptions of cannabis use within the healthcare community is essential for developing…
Open article record in new tab ↗BackgroundOne year after the partial legalisation of cannabis, the effects on cannabis use among young people in Germany were investigated.MethodsBased on twelve representative studies from 2008 to 2025, changes in the 12-month prevalence of cannabis use among 12- to 17-year-old adolescents and 18- to 25-year-old young adults were presented, and trends over time were estimated.ResultsAmong female and male adolesce…
Open article record in new tab ↗Globally, cannabis ranks third in psychoactive substance prevalence after nicotine and alcohol, with heavy use linked to psychosis, anxiety, and depression. However, real-time data on how legal reforms influence consumption remain scarce. This Ecological Momentary Assessment (EMA) study analyzed daily cannabis use patterns before and after Germany's recreational cannabis decriminalization in April 2024 in 49 indiv…
PurposeTo examine whether measures of health status and quality of life (QoL) were associated with cannabis use after cancer diagnosis.MethodsIndividuals who received care at an NCI-designated cancer center from 2018 to 2019 (n = 5,901) were invited to complete an online survey in 2022, of which 954 responded. We included 652 respondents in this study, which were weighted to represent the cancer center patient pop…
Open article record in new tab ↗BACKGROUND: Major depressive disorder (MDD) is a chronic, recurrent psychiatric illness with challenging management, partly due to the heterogeneity of clinical presentations, unpredictable course and episodes, and variable treatment responses. Cannabis may alleviate depression by promoting glutamate, GABA, and dopamine, but results from previous studies remain controversial or inconsistent. In this study, we aime…
Open article record in new tab ↗Background Many people who engage in heavy cannabis use do not seek treatment, and those who do are often met with long treatment wait times or high cost of services. Online treatment programs reduce barriers to accessing treatment in a timely manner. Online cannabis use treatment programs are effective, showing moderate effect sizes, particularly with text-based therapist support. Literature suggests brief therap…
BACKGROUND: Young adults report heightened cannabis use yet show gaps in cannabis-related risk knowledge. Risk knowledge gaps in young adults with diverse cannabis use experience and across countries with varying cannabis policies, as well as associations with knowledge levels were explored. METHODS: The International Cannabis Policy Study (ICPS) is a cross-sectional, web-based survey that uses non-probability sam…
Open article record in new tab ↗Background: Suicide prevention strategies in university settings largely rely on detecting explicit suicidal ideation. However, students experiencing severe psychiatric distress may not endorse suicidal thoughts and therefore remain unidentified by ideation-centered screening models. This study aimed to identify and clinically characterize university students with high depressive symptoms, poor sleep quality, and…
Non-medical use of cannabis (NmC) and/or opioids (NmO) can lead to adverse health effects (AHEs), yet the proportion of these harms attributable to adverse childhood experiences (ACEs) remains unclear. This study estimated the contribution of ACEs to AHEs from NmC and/or NmO among adults aged ≥18 years using 2019-2020 Behavioral Risk Factor Surveillance System data from Arizona and Massachusetts. We conducted a re…
Background: In experimental studies using the cue reactivity paradigm (CRP), classically conditioned substance craving is well-documented among individuals who use substances with trauma histories. However, the magnitude of this effect has not yet been quantified, nor have moderators of this relationship been identified [DeGrace, S., Romero-Sanchiz, P., Standage, C., & Stewart, S. H. (2022). A scoping review of th…
BackgroundCannabis use among university students has been increasingly linked to psychological distress; however, most evidence comes from Western contexts, and little is known about how cannabis use intersects with emotional functioning in non-Western settings. In Türkiye, where cannabis use remains illegal and highly stigmatized, students who use cannabis may represent a particularly vulnerable group. This study…
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