Readable research linked to original sources
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Browse normalized, publication-ready research with direct links to its evidence and source.
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Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
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Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
37 articles
Newest firstPURPOSE: Cannabis use is increasing among older adults. Given reported associations between delta-9-tetrahydrocannabinol (THC) and increased acute heart rate, there is concern regarding the impact of cannabis on cardiovascular health in older adults. Engaging in regular physical activity (PA) is associated with reduced heart rate and cardiovascular disease risk, but it has yet to be explored whether PA status infl…
Open article record in new tab ↗Objectives Cannabis is one of the most widely used psychoactive substances, and many adults meet the criteria for Cannabis Use Disorder (CUD). Prior research on its association with cardiovascular disease (CVD) has yielded mixed results. This study evaluates the relationship between CUD and CVD among ED patients. Methods This retrospective, propensity-matched analysis examined records from 67 US healthcare organiz…
Open article record in new tab ↗Hypertensionis one of the leading causes of cardiovascular disease and premature death worldwide, affecting more than 1.2 billion adults, with a significant part living in low- and middle-income countries. Pediatric hypertension is also a growing concern, with an estimated 4.5% of children in the United States affected. The 2024 European Society of Cardiology guidelines provide updated protocols for diagnosing and…
Open article record in new tab ↗Background An elevated risk of cardiovascular disease (CVD) and cerebrovascular disease (CBD) has been observed in patients with ICD-defined Neuromyelitis Optica (hereinafter referred to as NMO). However, population-based research on this topic remains limited. In this study, the risk of macrovascular events was compared between individuals with NMO and a matched population without NMO in Taiwan. Methods Data for…
Open article record in new tab ↗The principal objective served by this article is to identify key literature and provide an overview of the breadth of research in the field of machine learning applications on exposomics data with a focus on cardiovascular diseases. Secondarily, this study aimed at identifying common limitations and meaningful directives to be addressed in the future. Most of the identified literature focuses on Disease Understan…
Open article record in new tab ↗BackgroundTwo-thirds of Dutch cardiovascular risk management (CVRM) for patients at risk of cardiovascular disease is delivered in primary care practices. While individual risk scores are increasingly used during consultation, a population-level structure for risk-based patient outreach is not currently available. We therefore developed the PROSPERA programme, a multilevel intervention comprising population-level…
Cardiovascular disease (CVD) remains the leading cause of global mortality, with dietary habits playing a significant role in its prevention and management. Hempseed (Cannabis sativa L.) has gained recognition as a functional food due to its rich nutritional profile, including high-quality plant proteins, optimal omega-6 to omega-3 fatty acid ratios, and a variety of bioactive compounds such as tocopherols, phytos…
Open article record in new tab ↗Background: Kidney transplant recipients (KTRs) have an increased risk for cardiovascular disease (CVD) and cerebrovascular disease (CBD). This study investigated the risks of CVD and CBD following kidney transplantation. Materials and methods: This retrospective cohort study enrolled 3596 KTRs between 2003 and 2017. Propensity Score Matching (PSM) was performed to select patients without a kidney transplant, who…
Currently, cigarette smoking remains a global epidemic, with approximately one billion tobacco smokers worldwide, despite declines in use. Vaping products have become popular alternatives in recent years to conventional cigarettes. There has been a perception that vaping serves as a "healthier" alternative and has been increasing across all age groups, especially among teenagers and young adults. Vaping and its ad…
Cannabidiol (CBD) and other phytocannabinoids are gaining attention for their therapeutic potential in cardiovascular disease (CVD), the world's leading cause of death. This review highlights advances in understanding the endocannabinoid system, including CB1 and CB2 receptors, and the mechanisms by which CBD exerts anti-inflammatory, antioxidative, vasoprotective, and immunomodulatory effects. Preclinical and tra…
PurposeThere is a lack of sedentary behaviour interventions for individuals with spinal cord injury. Interventions designed for non-disabled individuals are unlikely to be generalisable to wheelchair-users with paraplegia, meaning a tailored approach is needed. ObjectiveThis study aimed to co-design a sedentary behaviour intervention using the Behaviour Change Wheel (BCW) for manual wheelchair-users with paraplegi…
BackgroundStatin treatments efficacy, safety and cost-effectiveness are well accepted, but the long-term impact on healthcare use is not fully understood. We assessed statin treatment effects on primary and hospital care use over time. MethodsThe UK Biobank population cohort with linked hospital admissions (N=501,807) and primary healthcare data (N=192,983) informed models of hospital admissions, hospital inpatien…
Open article record in new tab ↗BackgroundSubstantial geographic disparities in cardiovascular disease (CVD) mortality persist across the United States. The extent to which "place" reflects underlying socioeconomic and behavioral risk factors remains insufficiently explained. This study applies machine learning to quantify the determinants of these disparities. MethodsA cross-sectional analysis linked county-level 2019-2020 age-adjusted CVD mort…
Open article record in new tab ↗Artificial intelligence (AI) is transforming precision medicine, particularly in cardiovascular disease prevention and management. This bibliometric analysis examines the research land-scape from 2020 to 2024, focusing on AIs role in improving diagnostics, personalizing treatment, and advancing predictive healthcare. Using the PRISMA framework, VOSviewer, Harzings Publish or Perish, and Excel, 137 articles from Sc…
Open article record in new tab ↗Background Observational evidence investigating associations between cannabis use and blood pressure and hypertension is inconsistent. Methods Cross-sectional data from 3,255 participants at Exam 6 (2016-2018) of the Multi-Ethnic Study of Atherosclerosis (MESA) were analyzed, including self-reported cannabis smoking patterns, standardized measures of systolic blood pressure (SBP), diastolic blood pressure (DBP), p…
Open article record in new tab ↗Background Cannabidiol (CBD), a non-psychoactive phytocannabinoid of cannabis, is therapeutically used as an analgesic, anti-convulsant, anti-inflammatory, and anti-psychotic drug. There is a growing concern about the adverse side effects posed by CBD usage. Pregnane X receptor (PXR) is a nuclear receptor activated by a variety of dietary steroids, pharmaceutical agents, and environmental chemicals. In addition to…
Open article record in new tab ↗The global nutritional transition has led to the increased frequency and severity of chronic degenerative diseases worldwide, primarily driven by chronic inflammatory stress. At mealtimes, various pharmaceutical products aim to prevent such inflammatory stress, but they usually cause various systemic side effects. Therefore, the supplementation of natural and safe ingredients is a promising strategy to reduce the…
Open article record in new tab ↗Background Studies on cannabis use and adverse cardiovascular outcomes have reported conflicting results. Research on its relationship to calcified arterial plaque remains limited. Methods Cross-sectional data from 2152 participants at Exam 6 (2016-2018) in the Multi-Ethnic Study of Atherosclerosis (MESA) were analyzed, including self-reported cannabis smoking patterns and carotid artery calcification (CAC) as mea…
Cardiovascular disease (CVD) is a significant global health concern, requiring early detection and accurate prediction for effective intervention. Machine learning (ML) offers a data-driven approach to analyzing patient data, identifying complex patterns and predicting CVD risk factors like blood pressure (BP), cholesterol levels, and genetic predispositions. Our research aims to predict CVD presence using ML algo…
Open article record in new tab ↗Cardiovascular disease (CVD) causes millions of deaths worldwide each year. Despite the great progress in therapies available for patients with CVD, some limitations, including drug complications, still exist. Hence, the endocannabinoid system (ECS) was proposed as a new avenue for CVDs treatment. The ECS components are widely distributed through the body, including the heart and blood vessels, thus the action of…
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