Readable research linked to original sources
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Browse normalized, publication-ready research with direct links to its evidence and source.
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Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
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Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
43 articles
Newest firstObjective To evaluate trends in CHS hospitalizations in Canada, including their frequency and individual characteristics. Methods This study utilized data from the Canadian Institute for Health Information's Discharge Abstract Database to perform descriptive data analysis and employed JoinPoint Trend Analysis Software to analyze annual percent change (APC) and average annual percent change (AAPC) in hospitalizatio…
Open article record in new tab ↗Background Cannabis use is linked to treatment non-adherence and relapses in psychotic disorders. Antipsychotic medication is effective for relapse prevention in primary psychoses, but its effectiveness after cannabis-induced psychosis (CIP) remains unclear. Aims To examine the effectiveness of antipsychotic medication for relapse prevention following the first clinically diagnosed CIP. Method A cohort of 1772 pat…
ABSTRACTBackgroundResearch indicates that first‐episode psychosis (FEP) with cannabis use disorder (CUD) carries a substantial disease burden, but more granular clinical trajectories of cannabis‐related psychoses remain unclear. This study examines the clinical trajectories of first clinically diagnosed FEP&CUD and cannabis‐induced psychosis (CIP) in comparison with FEP without substance use disorder (SUD).Methods…
This study mapped the age- and region-specific risks of eye diseases in the Brazilian population, evaluating temporal trends and geographical inequalities in access to healthcare. Secondary data from DATASUS, covering the 27 Brazilian federative units from 2010 to 2024, were used, employing hierarchical negative binomial regression. A significant national increase in hospital admission rates was observed during th…
Open article record in new tab ↗BackgroundSocial determinants of health (SDOH)--including socioeconomic, demographic, and geographic factors--are closely linked to HIV/AIDS outcomes. This study assessed the association between SDOH and in-hospital AIDS-related mortality among low-income individuals in Brazil. MethodsWe conducted a cohort study using data from the 100 Million Brazilian Cohort, which includes individuals who applied for government…
Open article record in new tab ↗Measles is endemic in Kenya, mainly affecting young children, with low vaccination coverage leading to recurrent outbreaks. No published study has estimated the cost of treating hospitalised paediatric measles patients in Kenya. This study quantified the cost of treating measles from the healthcare provider and societal perspectives, identified the main cost drivers, and assessed the proportion of households likel…
Background Discharge against medical advice (DAMA) and inpatient admission (IA) among emergency department (ED) visits are two important outcomes in hospital utilization, while the first one has been mainly considered a negative outcome. Aims This study aimed to examine the association of socioeconomic factors with DAMA and IA among ED visits with substance use (age 12-64 years) before and after the COVID-19 pande…
Background and aims Cannabis use among U.S. older adults has risen rapidly over the past two decades. This study examined the changes in and correlates of cannabis-involved substance use treatment admissions among this demographic. Methods Using the 2000-2021 concatenated Treatment Episode Data Set-Admissions (TEDS-A) age 50+ (N=5,593,004), we fitted joinpoint regression models to examine changes in the percent of…
Open article record in new tab ↗Introduction We aimed to determine whether the trend in the rate of drug-induced hospitalisations and deaths changed during the first year of the COVID-19 pandemic in Australia. Methods Data comprised crude monthly rates (per 1,000,000 persons) of hospitalisations and deaths directly attributable to illicit drugs, prescription medicines, or medicines available without a prescription, nationally from 2011 to 2021.…
Open article record in new tab ↗For patients hospitalized with COVID-19, delirium is a serious and under-recognized complication, and people experiencing homelessness (PEH) may be at greater risk. This retrospective cohort study compared delirium-associated risk factors and clinical outcomes between PEH and non-PEH. This study used patient records from 154 hospitals discharged from 2020-2021 from the Texas Inpatient Public Use Data file. Study s…
Open article record in new tab ↗Objectives Individuals with angioedema (AE) are at high risk for airway compromise and often require endotracheal intubation. Patient factors predisposing one to airway compromise are not well described. The objective of this study is to examine whether substance use disorder (SUD) in patients with AE is associated with need for airway intervention. Methods This population-based retrospective cohort study compared…
Open article record in new tab ↗Introduction: Congestive heart failure (CHF) is a major global health challenge and the leading cause of hospitalization in the U.S., with disproportionately high 30-day readmission rates among low-income and minority communities. Social drivers of health and substance use both influence CHF outcomes, yet the effect of substance use on short-term readmissions remains understudied. This study evaluated the associat…
Introduction The prevalence of cannabis use continues to increase among certain populations in Canada. This study focussed on the increase in cannabis-attributable hospitalizations and emergency department (ED) visits from 2007 to 2020. Methods To estimate the counts of hospitalizations and ED visits attributable to cannabis use, we acquired record-level hospital discharge data with ICD-10 diagnostic information f…
Aim To determine the burden and nature of substance use presentations within a defined rural region and provide an estimate of the prevalence and subsequent local needs. Method Anonymised secondary data, based on hospital inpatient enquiry (HiPE) records dated 2010-2021 from three sites, were analysed using descriptive and inferential statistics. Result Despite similar gender distributions across the three hospita…
Open article record in new tab ↗Surveillance of acute lower respiratory tract disease (aLRTD) is fundamental for understanding population health burden and healthcare needs. COVID-19 altered the epidemiology of respiratory infections, but post-pandemic aLRTD incidence and severity remain underexplored in the UK. We conducted a prospective cohort study of adults ([≥]18 years) admitted to two Bristol hospitals (August 2020-July 2024) with symptoms…
Importance It is unclear whether cannabis use is associated with adverse health outcomes in patients with COVID-19 when accounting for known risk factors, including tobacco use. Objective To examine whether cannabis and tobacco use are associated with adverse health outcomes from COVID-19 in the context of other known risk factors. Design, setting, and participants This retrospective cohort study used electronic h…
Open article record in new tab ↗In June 2022, Thailand legalized recreational cannabis. Currently, cannabis is now the most consumed drug. Cannabis usage can increase inflammatory responses in the respiratory tract. Sharing of cannabis waterpipes has been linked to increased tuberculosis risks. Using a national in-patient databank, we aimed to 1) describe the spatiotemporal correlation between cannabis-related and tuberculosis hospital admission…
Open article record in new tab ↗Background Among patients diagnosed with schizophrenia, the presence of substance use poses an aggravating comorbidity, exerting a negative impact on the course of the disease, adherence to therapeutic regimens, treatment outcomes, duration of hospital stays, and the frequency of hospitalizations. The primary objective of the present study is to investigate the relationship between comorbid substance use disorders…
Background and hypothesis There is a paucity of research on treatment outcomes of patients with psychosis and cannabis use disorder (CUD). We aimed to compare the effectiveness of antipsychotics in reducing the risk of hospitalization in patients with first-episode psychosis (FEP) and co-occurring CUD. Study design We utilized a nationwide Swedish cohort of patients with longitudinal register data from the year 20…
BACKGROUND AND AIMS: Poor substance use-related health outcomes after release from prison are common. Identifying people at greatest risk of substance use and related harms post-release would help to target support at those most in need. The Alcohol Smoking and Substance Involvement Screening Test (ASSIST) is a validated substance use screener, but its utility in predicting substance-related hospitalisation post-r…