Readable research linked to original sources
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Browse normalized, publication-ready research with direct links to its evidence and source.
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Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
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Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
64 articles
Newest firstBACKGROUND: To estimate the prevalence of cannabis use among adults attending primary care, identify the age of initiation and associated sociodemographic characteristics, and describe patterns of dependence risk. METHODS: A cross-sectional descriptive study was conducted in three primary healthcare centres in the Barcelona metropolitan area. Adults aged 18 - 45 years were selected by simple random sampling. Telep…
Open article record in new tab ↗Background Cannabis use is rising among adults, yet few users receive structured medical supervision. Older users face unique risks necessitating specialized oversight. Given their longitudinal relationships and detailed understanding of patients' health and goals, primary care providers are well-positioned to guide decisions and education about medical cannabis (MC). Further, because of their expertise in managin…
Open article record in new tab ↗BackgroundHigh blood pressure (BP) is an often treatable cause of cardiovascular disease. We developed an intervention, featuring a cardiovascular expert team and a toolbox, to support healthcare professionals (HCPs) in hypertension management and enhance patient self-management. AimThis study evaluates the adoption and feasibility of this intervention. Design and SettingA mixed-methods study in general practices…
Open article record in new tab ↗BackgroundIncreasing Watch-group antibiotic use may be contributing to antimicrobial resistance burden in sub-Saharan Africa. We evaluated the effect of a community-based, co-created intervention bundle targeting all community-level healthcare providers and communities they serve, on Watch-group antibiotic use and patient management. MethodsIn a cluster-randomised, controlled trial in Burkina Faso (BF) and Democra…
BackgroundMetronidazole (MTZ) is a first-line antibiotic for several enteric infections. Its use is common in low-income countries, where most primary-care consultations are conducted by nurses. However, increasing resistance among some enteric pathogens is a growing concern. Using WHO guidelines, we conducted a register-based cross-sectional study to assess MTZ prescribing practices and their determinants in publ…
Open article record in new tab ↗BackgroundAdvice and Guidance (A&G) enables primary care clinicians to seek specialist input, supporting decision making and avoiding unnecessary referrals. The use of A&G has significantly expanded, accelerated by COVID19 and contractual changes. While A&G is intended to streamline elective care, concerns persist regarding workload shift, variable responsiveness, and system usability. Despite growing policy empha…
BackgroundStudent-run clinics (SRC) serve a unique role in healthcare by addressing the needs of underserved communities while providing medical students hands-on learning experiences. The Houston Outreach Medicine Education and Social Services (HOMES) Clinic is a SRC and a program of Healthcare for the Homeless - Houston that provides medical care to individuals experiencing unstable housing in Houston, Texas. Am…
Open article record in new tab ↗Background While cannabis use is prevalent among people with HIV (PWH), factors associated with higher-risk use require further study. We examined factors (mental health, sociodemographics, substance use, HIV clinical markers) associated with risk for cannabis use disorder (CUD) among PWH who used cannabis. Methods Participants included adult (≥ 18 years old) PWH from 3 HIV primary care clinics in Kaiser Permanent…
Open article record in new tab ↗Objectives This study aims to assess differences in analgesia prescribing in UK primary care between individuals with osteoarthritis who have a recorded exposure to cannabis use and those who do not. Methods This population-based retrospective cohort study included opioid-naïve patients with osteoarthritis (aged 25-85 years) who were active in Clinical Practice Research Datalink Aurum between 1 January 1995 and 15…
Open article record in new tab ↗Introduction On April 1st, 2024, Germany's cannabis legalisation bill entered into force. It is unknown what effect the legal changes could have, if any, on the prevalence of cannabis use. Preventive measures of cannabis-related health impacts are best possible if harmful use is recognised and addressed at an early stage. Our aim was to estimate the proportion of people who used cannabis in Germany that discussed…
Open article record in new tab ↗Background The post-Soviet country of Georgia has recently decriminalized recreational cannabis use, yet implementation of screening for cannabis use in clinical practice remains unclear. This study assesses relevant knowledge, attitudes, and practices of primary health care physicians (PCPs) regarding recreational cannabis use in the country of Georgia. Methods We conducted a mixed-method study, starting with a c…
Background On April 1st, 2024, Germany legalized recreational cannabis use under specific conditions. While policymakers extensively debated this change, the perspectives of healthcare providers who will address its consequences remain understudied. This study aims to characterize primary care physicians' experiences with cannabis-consuming patients and their expectations regarding the effects of legalization. Met…
Open article record in new tab ↗Background Non-fatal overdoses frequently precede fatal overdoses, thus identifying risk factors for non-fatal overdoses could help develop strategies to prevent substance related deaths. Aim This study aimed to identify patterns, circumstances and risk factors leading to non-fatal substance overdose in people experiencing homelessness. Method All recorded cases of non-fatal substance overdose from a population of…
Background Depression, anxiety, and cannabis use are growing, interconnected primary care concerns, but remain understudied due few health systems conducting systematic cannabis use screening. This study examines cannabis use and risk of cannabis use disorder (CUD) among primary care patients, comparing outcomes by depression and anxiety diagnoses and psychotropic prescriptions. Methods We assessed past three-mont…
Open article record in new tab ↗Aim To understand patterns of cannabis use and self-management experiences in patients with chronic disease during the post-legalization period in Thailand and to quantify such experiences and perceptions. Background Patients with chronic disease are a population in which disease self-management is potentially involved with the use of complementary and alternative medicines (CAMs). The recent changes in cannabis r…
BackgroundChronic kidney disease (CKD) affects approximately 10% of adults in England. <1% progress to end stage-kidney disease (ESKD), significantly impacting health-related quality of life with high healthcare costs. CKD is associated with cardiovascular disease risk. New therapies to improve outcomes highlight the need for effective risk stratification. AimTo explore primary care teams views and experiences of…
AimsTo investigate the association between depression history, timing, and progression of diabetes treatment in type 2 diabetes (T2D). MethodsWe conducted a cohort study using primary care records from the Clinical Practice Research Datalink Aurum database (2011-2023). Adults with T2D initiating oral glucose-lowering monotherapy (index) were included. Depression history, identified using clinical codes, was catego…
Open article record in new tab ↗1.The prescribing of multiple medicines to one individual, or polypharmacy, is increasingly common. While the use of multiple medications by a patient is often appropriate, in some cases prescribed medicines may not have the intended benefit and may even cause harm, and it is important to understand the clinical and economic implications of polypharmacy and interventions to optimise prescribing. In the UK, most on…
Open article record in new tab ↗BackgroundLarge Language Models (LLMs) offer promising applications in healthcare, including drafting referral letters. However, access to LLMs specifically designed for medical practice remains limited. While ChatGPT is widely available, its ability to generate comprehensive and clinically appropriate neurology referral letters remains uncertain. This study aimed to systematically evaluate the completeness and qu…
Open article record in new tab ↗BackgroundCommunity antiretroviral therapy (ART) delivery programmes allow people living with HIV (PLWH) to collect treatment nearer to home rather than having to attend clinics. However, delays in laboratory based viral load (VL) testing can prevent timely assessment of eligibility for community ART prescription renewals. We aimed to determine if point-of-care VL testing in the clinic could prevent delayed renewa…