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Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
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Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
17 articles
Newest firstThe present study was focused on the experimental and machine learning approach to evaluate the diesel engine parameters behavior with hemp biodiesel blends enriched with nano additives (Al2O3, TiO2 and MWCNT's) at different loads. The Hemp biodiesel was characterized by using FTIR and GC-MS analysis. The nano additives were examined through a SEM and XRD analysis for identifying the morphological structure and cr…
Open article record in new tab ↗IntroductionCardiovascular disease (CVD) is an important complication of type 2 diabetes (T2D). Current incident CVD-prediction models use single baseline measurements and achieve moderate performance in people with T2D, with C-indices around 0.7. Modern healthcare registries contain repeated measurements of HbA1c, LDL-cholesterol and eGFR, which could carry incremental predictive value. However, the added value o…
Acute cannabinoids toxicity is an alarming toxicological problem. The current study aimed to compare children and adults with acute natural cannabinoids toxicity and highlight cases with acute synthetic cannabinoids (SCs) toxicity. This retrospective cross-sectional study was conducted on patients with acute cannabinoids toxicity admitted to Tanta University Poison Control Center from January 2019 to December 2023…
Open article record in new tab ↗Background and aims Risky alcohol use in young adulthood is a significant public health concern. Understanding the predictors of risky drinking during this period is essential for prevention. This study aimed to measure the predictive accuracy of ensemble machine learning and identify the most important predictors of risky alcohol use in early adulthood. Design and setting Secondary analysis of the Longitudinal St…
Open article record in new tab ↗Background and hypothesis Transition to psychosis rates within ultra-high risk (UHR) services have been declining. It may be possible to 'enrich' UHR cohorts based on the environmental characteristics seen more commonly in first-episode psychosis cohorts. This study aimed to determine whether transition rates varied according to the accumulated exposure to environmental risk factors at the individual (migrant stat…
BackgroundPressure injuries (PIs) place a substantial burden on healthcare systems worldwide. Risk stratification of those who are at risk of developing PIs allows preventive interventions to be focused on patients who are at the highest risk. The considerable number of risk assessment scales and prediction models available underscore the need for a thorough evaluation of their development, validation and clinical…
In medical diagnosis context, consideration for missing diagnosis and false diagnosis of disease types are important clinical considerations for disease treatment decisions. Effect and impact of disease types especially on others forms the basis for critical clinical decisions. Impact and consequences varies across disease types especially for communicable and non-communicable diseases. Increasing use of predictiv…
Open article record in new tab ↗Cannabis sativa L. is a versatile crop attracting increasing attention for food, fiber, and medical uses. As a dioecious species, males and females are visually indistinguishable during early growth. For seed or cannabinoid production, a higher number of female plants is economically advantageous. Currently, sex determination is labor-intensive and costly. Instead, we used rapid and non-destructive hyperspectral m…
BackgroundClinicians and people of reproductive age would benefit from a reliable way to identify who is, or is not, likely to become pregnant in the next year, to direct health advice. The 14-item Desire to Avoid Pregnancy (DAP) Scale is predictive of pregnancy; this paper compares it with other ways of assessing pregnancy preferences to shortlist options for clinical implementation. MethodsA cohort of 994 UK wom…
Open article record in new tab ↗BackgroundThe coronavirus disease 2019 (COVID-19) presents an urgent threat to global health. Identification of predictors of poor outcomes will assist medical staff in treatment and allocating limited healthcare resources. AimsThe primary aim was to study the value of D-dimer as a predictive marker for in-hospital mortality. MethodsThis was a cohort study. The study population consisted of hospitalized patients (…
Open article record in new tab ↗To understand the role of environment in the pathoetiology of psychosis spectrum disorders, research has thus far mainly investigated the effects of single exposures in isolation, such as the association between cannabis use and schizophrenia. However, this approach fails to acknowledge the complexity of the exposome, which represents the totality of the environment involving many exposures over an individual's li…
Open article record in new tab ↗Previously, we established an estimated exposome score for schizophrenia (ES-SCZ) as a cumulative measure of environmental liability for schizophrenia to use in gene-environment interaction studies and for risk stratification in population cohorts. Hereby, we examined the discriminative function of ES-SCZ for identifying individuals diagnosed with schizophrenia spectrum disorder in the general population by measur…
BACKGROUND: Mental health policy makers require evidence-based information to optimise effective care provision based on local need, but tools are unavailable. AIMS: To develop and validate a population-level prediction model for need for early intervention in psychosis (EIP) care for first-episode psychosis (FEP) in England up to 2025, based on epidemiological evidence and demographic projections. METHOD: We used…
COVID-19 pandemic has burdened healthcare systems, necessitating the development of mortality prediction scores to guide clinical decisions and resource allocation. 4C ISARIC mortality score was developed and validated on a British cohort. ObjectivesExternal validation of the score in the setting of a large Saudi Arabian ICU. MethodRetrospective chart review of COVID-19 patients admitted to ICU of King Saud Medica…
Open article record in new tab ↗Determining the clinically optimal dose in methadone maintenance therapy (MMT) is a time-consuming procedure, which considers clinical signs and symptoms.To perform a quantitative trait locus association for identifying genetic variants for MMT dosage that underlie heroin addiction and methadone metabolism and then integrate several genotypic and phenotypic factors are potential predictors for clinically optimal M…
Open article record in new tab ↗Objective: To identify new biochemical markers for endometrial cancer (EC). Recent evidence suggests that members of the endocannabinoid system (N-acylethanolamines) that bind to and activate receptors that are dysregulated in EC are involved in this tumour's biology. These observations suggest increased N-acylethanolamine levels in the tissue that might appear in plasma and could be used as disease biomarkers. Me…
Open article record in new tab ↗Background The ability to accurately predict operative duration has the potential to optimise theatre efficiency and utilisation, thus reducing costs and increasing staff and patient satisfaction. With laparoscopic cholecystectomy being one of the most commonly performed procedures worldwide, a tool to predict operative duration could be extremely beneficial to healthcare organisations. Methods Data collected from…