Readable research linked to original sources
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Browse normalized, publication-ready research with direct links to its evidence and source.
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Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
Loading articles data…
Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
45 articles
Newest firstBACKGROUND: This study aimed to develop and validate a highly sensitive and reproducible liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for the simultaneous determination of 5F-MDMB-PICA and MDMB-4en-PINACA in human serum, ensuring suitability for both forensic and clinical toxicology applications. METHODS: Drug-free serum samples were fortified with target analytes, extracted through solid-phase…
Open article record in new tab ↗Men who have sex with men (MSM) have an elevated risk of adverse outcomes associated with cannabis use. Many studies have been conducted globally; however, there is a lack of research regarding the existing status and factors associated with cannabis use among MSM in Nepal. Therefore, this study aimed to examine the characteristics and factors associated with cannabis use among MSM in Nepal. A cross-sectional resp…
Open article record in new tab ↗RATIONALE: Hepatopancreatoduodenectomy (HPD) is a surgical procedure utilized for the curative-intent resection of biliary tract malignancies. However, there is a paucity of literature documenting the application of robotic-assisted HPD in case of gallbladder cancer (GBC) with invasion into the common bile duct (CBD) in patients who had no jaundice. PATIENT CONCERNS: One week before admission, a 58-year-old female…
Hypertensionis one of the leading causes of cardiovascular disease and premature death worldwide, affecting more than 1.2 billion adults, with a significant part living in low- and middle-income countries. Pediatric hypertension is also a growing concern, with an estimated 4.5% of children in the United States affected. The 2024 European Society of Cardiology guidelines provide updated protocols for diagnosing and…
Open article record in new tab ↗This retrospective cohort study evaluated the tolerability, efficacy, and safety of adjunctive cannabidiol (CBD) therapy in pediatric-onset intractable epilepsy across diverse genetic and nongenetic etiologies. Twenty-nine patients aged 6 to 24 years, treated at Korea University Hospitals between April 2019 and May 2024, were included. The median follow-up duration was 14.3 months. Confirmed genetic etiologies inc…
Open article record in new tab ↗The link between sedentary behavior and substance use is drawing increased attention, especially as marijuana use becomes more prevalent in the U.S. studies suggest that excessive sedentary behavior negatively impacts health, and this research aims to explore its relationship with marijuana use to better understand its potential health implications. This cross-sectional study analyzed data from 7122 participants i…
Rationale Endoscopic retrograde cholangiopancreatography (ERCP) with endoscopic nasobiliary drainage is the standard treatment for common bile duct (CBD) stones. Post-ERCP abdominal pain is typically linked to complications like pancreatitis, perforation, or cholangitis. However, cases of nonspecific abdominal pain caused by duodenal ulcers induced by the nasobiliary drainage tube after ERCP have not been reported…
Open article record in new tab ↗The purpose of the study was to examine the association between depression and substance abuse and to assess their prevalence and associated factors. A cross-sectional design was employed. To collect data for the present study, 2 scales (Beck depression inventory and Alcohol, Smoking, and Substance Involvement screening Test [ASSIST]) was administered to students. Two hundred fifty seven Addis Ababa Institute of T…
Open article record in new tab ↗Rationale Adenomyomatosis is a rare benign condition characterized by epithelial proliferation and diverticular formation in the gastrointestinal tract, most commonly affecting the gallbladder. Its occurrence in the bile duct is uncommon but significant, as it can cause biliary obstruction, cholestasis, and abdominal pain-symptoms that closely mimic early-stage cholangiocarcinoma. This overlap creates diagnostic c…
Open article record in new tab ↗The global use of cannabinoid-based medications is expanding due to increasing evidence supporting their therapeutic potential. However, in Saudi Arabia, their adoption is influenced by cultural and regulatory factors. Pharmacists play a pivotal role in guiding the safe use of these therapies. This study aimed to assess the knowledge and attitudes of hospital pharmacists in Jeddah regarding Food and Drug Administr…
Persons with HIV (PWH) experience high levels of pain. We examined the relationship of pain severity with use of cannabis and prescription opioids among PWH. This cross-sectional study evaluated associations between self-reported pain (moderate/severe vs mild/none) and cannabis and prescription opioid use in a primary care sample of PWH enrolled in an alcohol use treatment study at Kaiser Permanente, San Francisco…
Globally, the Coronavirus disease (COVID-19) pandemic in 2019 has accelerated the adoption of telehealth technologies. The implementation of the Saudi Telemedicine Network (STN) and other digital health initiatives, such as the telehealth clinic (THC) at King Abdullah bin Abdulaziz University Hospital (KAAUH), exemplifies this trend in Saudi Arabia. The aim of this study was to explore the patients' experience of…
Laparoscopic duodenum-preserving pancreatic head resection (LDPPHR) has been widely reported. However, due to the challenges involved in performing total pancreatic head resection during operation, there are few studies reporting it. Between November 2016 and October 2022, we performed laparoscopic duodenum-preserving total pancreatic head resection (LDPPHRt) on 64 patients in the Department of Hepatobiliary Surge…
Abstract We aimed to examine trends and characteristics of substance use (opioid, cocaine, marijuana, and heroin) among hospitalized homeless patients in comparison with other hospitalized patients in 3 states.This was a cross-sectional study, based on the 2007 to 2015 State Inpatient Data of Arizona, Florida, and Washington (n = 32,162,939). Use of opioid, cocaine, marijuana, heroin, respectively, was identified…
Open article record in new tab ↗Background Cannabis use has been steadily rising in the United States and can have multiple adverse effects, including cannabis-induced acute pancreatitis. This study aims to collate and highlight the significant demographics, clinical presentation, and outcomes in patients with cannabis-induced acute pancreatitis. Method A systematic literature search of electronic databases for peer-reviewed articles was conduct…
Open article record in new tab ↗Abstract Early or multiple recurrences of symptomatic common bile duct (CBD) stones are troublesome late complications after endoscopic stone removal. We aimed to determine the factors related to early or multiple recurrences of CBD stones.We retrospectively analyzed patients who underwent endoscopic CBD stone extraction in a single institute between January 2006 and December 2015. Patients were divided into 2 gro…
Abstract Common bile duct (CBD) stone is a commonly encountered disease that is associated with various clinical presentations ranging from the mild form of biliary colic to the severe complication of acute cholangitis. Recently, diabetes mellitus (DM) has been linked to the development of biliary diseases; however, no data regarding the association of DM with acute cholangitis development in the setting of CBD st…
Open article record in new tab ↗ICG fluorescence (ICGF) guidance during laparoscopic cholecystectomy (LC) is gaining wider acceptance. While the accruing data largely addresses ICGF guidance during LC in patients with uncomplicated gallstone disease (UGS) and acute cholecystitis, there is a paucity of data related for complicated gall stone disease (CGS) such as choledocholithiasis, bilio-enteric fistula, remnant gall bladder, etc. The purpose o…
Open article record in new tab ↗Purpose of review Prescribed and non-prescribed cannabis use is common. Providers in specialties treating chronic pain - primary care, pain management, and neurology-will be coming across medical cannabis as a treatment for chronic pain, regardless of whether they are prescribers. It is important to be aware of the systemic and syndromic complications of acute and chronic cannabis use in the differential diagnosis…
Open article record in new tab ↗Introduction Therapeutic laparoscopic-assisted transgastric endoscopic retrograde cholangiopancreatography (LA-ERCP) is a safe and effective technique for patient who are unable to receive endoscopic or percutaneous transhepatic treatment. This procedure shows a high overall success rate in managing pancreaticobiliary complications, comparable to that of ERCP. Patient concerns A 51-year-old man had abdominal pain…