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Browse normalized, publication-ready research with direct links to its evidence and source.
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Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
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Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
260 articles
Newest firstHighlights Public health relevance—How does this work relate to a public health issue? The stress of transitioning to and from adulthood may have a negative impact on college student performance and health outcomes.While in college, students face high rates of mental health disorders (anxiety, depression, suicidal ideation), substance use disorder, severe sleep deprivation, and poor nutrition. Public health signif…
Open article record in new tab ↗Neuropsychiatric disorders represent a significant global health burden. Despite decades of research, current treatments typically provide only symptomatic relief, rather than addressing the underlying mechanisms of these conditions. Historically, research focused on the dopaminergic and serotonergic systems, which are deeply involved in the pathophysiology of many mental health disorders, including depression, sc…
AIMS: Substance-induced mental disorders (SIMD) are an under-recognized consequence of psychoactive substance use, despite major implications for treatment needs, health service demand and outcomes. In the context of British Columbia's (BC's) ongoing toxic drug emergency, we aimed to (1) estimate the incidence and prevalence of SIMD in the provincial population and (2) describe socio-demographic, geographic, clini…
Background/Objectives: This systematic review aims to synthesize existing evidence on the impact of nursing interventions based on Watson's Theory of Human Caring (THC) on women's mental health and to provide an evidence-based framework for clinical practice. Methods: The review followed the PRISMA guidelines and was registered in the PROSPERO database (Registration No: CRD420251111577). A comprehensive literature…
Open article record in new tab ↗Highlights What are the main findings? Anxiety is prevalent in both recreational and medical cannabis users with both groups endorsing clinically significant anxiety levels.Qualitative analyses revealed the anxiolytic and anxiogenic experiences of anxiety extended beyond traditional binary diagnostic categories and supports the use of the Research Domain Criteria (RDoC) framework as a valuable approach for underst…
Open article record in new tab ↗Background Musculoskeletal injuries are common among athletes and can negatively affect both physical and psychological wellbeing. Beyond physical disability, injuries have been linked to poor mental health, loss of athletic identity, and increased substance use. In low- and middle-income countries (LMICs), where awareness and management of mental health remain limited, the psychological burden of sports injuries…
IntroductionUniversity is a pivotal life-course transition in which academic, social and geographic changes intersect with heightened risk for mental disorders and maladaptive behaviors. Health Mode On (HMO) and its longitudinal expansion Health Mode On Plus (HMO+), funded by the Italian Ministry of University and Research (MUR) competitive PRO-BEN 1 and PRO-BEN 2 calls, couple harmonized surveillance with a stepp…
ABSTRACTBackground: Childhood maltreatment (CM) is associated with an increased risk of mental disorders, with oxidative stress (OS) being proposed as a potential mediator. However, it remains unclear whether exposure to specific types of CM during distinct developmental periods is associated with altered OS levels.Objective: This study aimed to explore the association between CM type and timing and OS in young ad…
Introduction Longitudinal, population-based studies of how youth substance use (SU) varies by sexual attraction, sex and their interaction remain scarce, especially in Europe. This study examines poly-SU (PSU) trajectories at 17, 20 and 24; disparities between sexual minority (SM) youth and heterosexual (HET) youth regarding these trajectories; and their correlates. Methods We obtained data from the Zurich Project…
Open article record in new tab ↗PurposeTo examine whether measures of health status and quality of life (QoL) were associated with cannabis use after cancer diagnosis.MethodsIndividuals who received care at an NCI-designated cancer center from 2018 to 2019 (n = 5,901) were invited to complete an online survey in 2022, of which 954 responded. We included 652 respondents in this study, which were weighted to represent the cancer center patient pop…
Open article record in new tab ↗Introduction Bullying remains a major public health concern among adolescents and is associated with adverse mental health and behavioral outcomes. Evidence from low- and middle-income countries, including Ecuador, remains limited. Methods We conducted a cross-sectional study using data from the Ecuadorian version of the Youth Risk Behavior Surveillance System (YRBSS). Associations between school bullying, cyberbu…
Open article record in new tab ↗Background More severe substance use, defined as higher scores on validated measures of problematic use, is increasing within young adult populations. Substance use has been associated with mild traumatic brain injury (mTBI) and elevated symptoms of depression and anxiety. We aimed to understand the relationship between these factors and sex differences in a university sample. Method 894 university students (372 m…
Open article record in new tab ↗Depersonalization/derealization (DPDR) involves feeling detached from one's body, thoughts, or emotions and is often triggered by trauma, stress, mental health issues, or drug use, typically causing high distress. Similar experiences are also reported in meditation contexts, where they are often described as positive, insightful, and meaningful. However, no study has systematically compared DPDR-like experiences a…
Open article record in new tab ↗AbstractBackgroundIndividuals with inflammatory bowel disease (IBD) experience mental health disorders at rates 1.5-2 times higher than the general population. Many are affected during major life stages such as pregnancy, yet data on how IBD influences anxiety and depression in pregnancy remain limited.MethodsThis retrospective survey study included patients from the “Preconception and Pregnancy in IBD” clinic who…
Open article record in new tab ↗Introduction As cannabis policies become more liberal, and products increasingly potent, it is important to monitor changes in rates of cannabis use and those at risk of harm. We used data from the largest national mental health survey in Australia to examine changes in prevalence, associations and comorbidity of past 12-month cannabis use and cannabis use disorder (CUD) from 2007 to 2020-22. Methods Data were dra…
OBJECTIVES: (1) To compare sociodemographic characteristics, psychopathology, and substance use patterns among women diagnosed with substance use disorder (SUD) who experienced physical abuse (PA), sexual abuse (SA), or both (PSA); (2) to describe ages of onset; (3) to evaluate the impact of PA, SA, and their interaction on clinical outcomes. METHODS: Observational retrospective study with patients from PROMUD (Dr…
Background Endoscopic retrograde cholangiopancreatography (ERCP) is often performed under conscious sedation, which may increase pain and dissatisfaction. Mental health conditions may influence patient-reported experience measures (PREMs), including tolerability. This study explores the association between pre-existing anxiety and/or depression and ERCP tolerability using the validated Patient-Reported Scale for T…
Background The COVID-19 pandemic disproportionately affected certain populations, with intimate partner violence (IPV) survivors facing heightened risks of adverse health outcomes. This study examined whether women who experienced IPV during Ontario's COVID-19 lockdowns were more likely to report negative behavioural, psychological, and physiological health outcomes compared to women who did not experience IPV . M…
Background and aims Epidemiologic research suggests that adolescent cannabis use is associated with psychological distress (i.e. depression and anxiety symptoms); however, most studies have relied on 20th-century data, when cannabis was significantly less potent than today. This study aimed to estimate the association between adolescent cannabis use and psychological distress using contemporary population-based da…