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Browse normalized, publication-ready research with direct links to its evidence and source.
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Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
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Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
235 articles
Newest first[This corrects the article DOI: 10.3389/fpsyt.2026.1816611.].
Open article record in new tab ↗Introduction The COVID-19 pandemic was associated with high levels of depression and anxiety among pregnant individuals in the UK, as shown previously in the EPPOCH cohort. However, the relationships between these psychological burdens, pandemic-related stressors, and substance use in the prenatal period have not been systematically investigated. Methods To address this gap, we conducted a cross-sectional analysis…
Cannabinoid hyperemesis syndrome (CHS) is a rare but increasingly recognized condition among chronic cannabis users, characterized by cyclic nausea, vomiting, and relief with hot bathing. During pregnancy, CHS may mimic hyperemesis gravidarum (HG), complicating diagnosis and management. We report the case of a 24‐year‐old pregnant patient who presented at 20 weeks′ gestation with recurrent nausea, vomiting, and la…
The human maternal-fetal interface is characterized by mosaic intermingling of maternal and fetal cells1. Yet the underlying cellular, molecular and spatial programmes remain incompletely defined. Here we generate a comprehensive atlas of the human maternal-fetal interface across normal pregnancies from early gestation to term by integrating large-scale paired single-nucleus transcriptomic and chromatin accessibil…
Open article record in new tab ↗Introduction Prenatal substance exposure is an increasing problem that has been linked to multiple neurodevelopmental impairments and alterations to brain functional connectivity. Methods Behavioral scores and functional network correlation data were obtained from the Adolescent Brain Cognitive DevelopmentSM (ABCD) Study. First, behavioral scores based on the child behavioral checklist were tested for associations…
Open article record in new tab ↗IntroductionCannabis use during pregnancy and the postpartum period has increased in recent years, raising clinical concerns regarding maternal and infant health, particularly during lactation. However, evidence regarding Δ9-THC concentrations in breast milk during the early postpartum period and their relationship with other biological matrices remains limited.ObjectiveThis study aimed to assess Δ9-THC concentrat…
Open article record in new tab ↗Aims To estimate the prevalence of prenatal cannabis use in Michigan, USA, using self-reports and urine toxicology and to examine factors associated with use. Design Observational study using data from the Michigan Archive for Research on Child Health (MARCH) cohort, part of the National Institutes of Health's Environmental influences on Child Health Outcomes (ECHO) program. It is a prospective statewide pregnancy…
Prenatal tobacco (PTE) and tobacco cannabis co-exposure (PTCE) are associated with higher risk for child externalizing problems. However, developmental mechanisms for the PTE association and the PTCE related associations are poorly understood. We tested multiple mechanistic developmental pathways (emotion regulation, temperament, maternal negative mood, and continued postnatal tobacco exposure) from PTE and PTCE t…
Open article record in new tab ↗BackgroundPregnant patients experiencing incarceration with a history of substance use face complex challenges accessing reproductive health services. Despite research indicating interest in these services, contraception counseling and services are often excluded from routine carceral health services.ObjectivesWe sought to examine the postpartum contraceptive plans and fulfillment of pregnant patients in the North…
OBJECTIVE: We aimed to explore how women living in places with legalized recreational cannabis perceive perinatal cannabis use, and how legalization potentially impacts their experiences. METHODS: Between September 2024 and December 2025, we searched databases including PubMed, CINAHL, Scopus, PsycINFO, and Web of Science. All research reports were screened and evaluated based on the inclusion and exclusion criter…
Open article record in new tab ↗Background Few studies have examined the intergenerational impact of maternal childhood maltreatment (MCM) in the context of prenatal substance exposure (PSE). This study investigates whether PSE is part of the pathway of MCM or an independent risk factor affecting offspring psychopathology. Methods Participants were 284 birth mother-child (44% male) dyads, primarily Black, low-income, enrolled at birth. Exposure…
Objective Prenatal cannabis use has more than doubled in recent years, disproportionately affecting birthing people with lower incomes and mental health conditions. Despite this trend, research remains fragmented, and the voices of birthing people who use cannabis are largely absent. This study aimed to explore multidimensional influences on prenatal cannabis use, centering the lived experiences of those directly…
Open article record in new tab ↗Cannabis use during pregnancy or lactation is a key topic in healthcare today. It is recommended that patients abstain from perinatal use and healthcare providers are encouraged to discuss use with patients. However, some perinatal individuals continue to use even once educated about the risks. For them, a nuanced approach to counseling that goes beyond warnings of risks is required to promote health and maintain…
Open article record in new tab ↗Background Prenatal cannabis use is becoming increasingly more commonplace. However, cannabis exposure is linked to adverse pregnancy outcomes, including gestational hypertension, preeclampsia, and preterm birth. The aim of this study was to determine the morphological and molecular effects of prenatal cannabinoid exposure on the placenta. Methods Pregnant Sprague-Dawley rats were exposed daily to vaporized THC (1…
Open article record in new tab ↗BackgroundThe ECAIL trial, launched in 2017, targets hard-to-reach families and evaluates a multicomponent childhood obesity prevention intervention. At a maternity hospital in Lille, France, healthcare providers screened pregnant women experiencing social vulnerability, and dietitians delivered a home-based intervention until age 2. The COVID-19 pandemic led to a six-month suspension in 2020. This study compared…
We describe the harmonisation of five UK electronic birth cohorts to the Observational Medical Outcomes Partnership (OMOP) Common Data Model, creating a large-scale, standardised resource for maternal and child health research. The Mother and Infant Research Data Analysis (MIREDA) partnership developed and implemented reproducible guidelines for mapping maternal-infant relationships and identifying pregnancy episo…
Objectivedetermine the prevalence of Obstetric Violence (OV) and its correlates in Bafoussam. Methodologywe conducted a quantitative hospital-based survey at the Bafoussam Regional Hospital (BRH) and the Mifi District Hospital (MDH) from October 15th to December 15th 2023.Our sampling was consecutive and exhaustive including women in post-partum wards. We conducted face-to-face interviews using a pretested questio…
Objective Despite increased recreational cannabis legalization (RCL) in the US in recent years, little is known about cannabis advice received at prenatal care visits. We aimed to examine cannabis screening and counseling occurring at prenatal care visits, including adherence of advice to current clinical guidelines and variations by RCL status. Methods In this repeated cross-sectional study, we used 2017-2020 Pre…
Open article record in new tab ↗Introduction:Perinatal intimate partner violence (IPV) and perinatal cannabis and nicotine product use are common and associated with negative maternal–infant health outcomes. Substance use coercion (SUC), which involves abusive partners’ controlling behaviors related to substance use, has not been studied for cannabis and nicotine products. Perinatal individuals may be particularly vulnerable to SUC, and this stu…
Objectives Cannabis legalization has triggered an increase in prenatal cannabis use. Given that tobacco is commonly co-used with cannabis, determining outcomes associated with prenatal cannabis and tobacco co-exposure is crucial. While literature exists regarding the individual effects of prenatal cannabis and tobacco exposure on childhood behaviour, there is a gap regarding their combined use, which may have inte…
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