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Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
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Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
21 articles
Newest firstABSTRACTIntroductionMedicinal cannabis prescribing in Australia has increased markedly, including for psychiatric indications where evidence of benefit is limited and of low certainty. The rise of highly commercialised prescribing models has raised concerns regarding patient safety, particularly for those with pre‐existing psychiatric or addiction vulnerabilities.Case PresentationThis case series describes three y…
Open article record in new tab ↗Introduction Bladder cancer (BC) is rarely associated with common bile duct (CBD) obstruction. We report a case of BC with peritoneal invasion and rectal involvement complicated by bilateral ureteral and biliary obstruction. Case presentation A 77-year-old man presented with abdominal pain. Imaging revealed a bladder tumor with suspected muscle invasion, rectal obstruction, and bilateral hydronephrosis. Urothelial…
Open article record in new tab ↗Cannabinoid hyperemesis syndrome (CHS) is a rare but increasingly recognized condition among chronic cannabis users, characterized by cyclic nausea, vomiting, and relief with hot bathing. During pregnancy, CHS may mimic hyperemesis gravidarum (HG), complicating diagnosis and management. We report the case of a 24‐year‐old pregnant patient who presented at 20 weeks′ gestation with recurrent nausea, vomiting, and la…
Background Trigeminal neuropathic pain (TNP) is a chronic and debilitating condition frequently resistant to conventional pharmacological therapies. Although cannabinoids have emerged as a potential adjunctive treatment, objective clinical documentation of their effects in orofacial neuropathic pain remains limited. Case reports We report two female patients with refractory TNP-one post-traumatic and one idiopathi…
Postcholecystectomy clip migration (PCCM) is a rare but recognized complication following cholecystectomy. The clinical presentation of PCCM often mimics that of choledocholithiasis, with symptoms including right upper quadrant pain and obstructive jaundice. Although the exact mechanisms underlying clip migration remain unclear, several theories have been proposed in the literature. While most cases occur shortly…
Open article record in new tab ↗Cannabis use in older adults may have a broad range of effects in older adults impacting Mind, Mobility, Medications, Multi-complexity, and what Matters Most.
Open article record in new tab ↗Pancreatic and biliary tract injuries from blunt abdominal trauma are rare in children. Common bile duct (CBD) strictures secondary to pancreatic trauma are even more uncommon, and management traditionally involves surgery. We report a 9-year-old boy who developed a severe distal intrapancreatic CBD stricture after blunt pancreatic trauma during an all-terrain vehicle (ATV) accident. Endoscopic ultrasound (EUS) an…
Open article record in new tab ↗Cholecystocolonic fistula (CCF) is an uncommon complication of gallstone disease and is usually diagnosed intraoperatively. Concomitant choledocholithiasis and acute cholangitis create competing priorities: urgent biliary drainage and definitive treatment of the fistula. A 78-year-old woman presented with 3 days of upper abdominal pain, fever, vomiting and jaundice. She was febrile and hypotensive but stabilised a…
Open article record in new tab ↗Schizophrenia-spectrum disorders are characterized by psychotic symptoms, including hallucinations, delusions, and disorganized thinking. Schneider's first-rank symptoms (FRS)-including thought broadcasting and experiences of external control-are clinically salient but not ergonomic and require careful differential diagnosis. The emergence of new-onset psychosis in midlife, particularly in individuals without prio…
Open article record in new tab ↗Early recognition of intrabiliary rupture in cystic echinococcosis is essential to prevent serious complications. Timely imaging and minimally invasive interventions such as endoscopic retrograde cholangiopancreatography, combined with antiparasitic therapy, can effectively manage biliary obstruction and reduce morbidity in complex cases.
Open article record in new tab ↗This case report describes the management of a 40-year-old female who developed a saddle pulmonary embolism (PE) following open reduction and internal fixation (ORIF) of a distal tibia fracture. The patient had no significant past medical history except for regular cannabis use. Postoperatively, she developed a deep vein thrombosis (DVT) and a saddle PE, which were managed with catheter-directed thrombectomy and a…
Background Delta-9-tetrahydrocannabiphorol (Δ9-THCP) is a potent phytocannabinoid found naturally in the cannabis plant in small quantities. This cannabinoid is noted to potently bind to cannabinoid receptor 1 and cannabinoid receptor 2 and is reported to be highly psychoactive. A small amount of Δ9-THCP is found naturally, which led to its isolation and synthetic production. This isolate is beginning to be sold a…
Open article record in new tab ↗A child died in the emergency room of a local hospital a few hours after ingesting a substance the color of cork and the consistency of earth. At home, a modest amount of resinous substance was found. At the hospital, the child exhibited alterations in walking, balance, and consciousness. Intubation was needed for the onset of dyspnea, so fentanyl and ketamine were administered during the procedure. A sample of bl…
Open article record in new tab ↗Bile duct perforation is a rare, serious complication of congenital biliary dilatation (CBD). While traditionally managed with a two-stage surgical approach, recent reports suggest that one-stage, minimally invasive approaches may be feasible. We present the case of a 13-month-old female who developed bile duct perforation associated with a protein plug in the common channel. Following the correction of coagulopat…
Background Corticobasal degeneration (CBD) presents with a range of clinical phenotypes, making diagnosis challenging. We report the clinical course of a patient with autopsy-confirmed CBD who initially presented with cognitive impairment and apathy, without motor symptoms. Case presentation A 51-year-old man presented to our hospital with decreased motivation, amnesia, and executive dysfunction. Memory disturbanc…
Biliary complications after orthotopic liver transplantation (OLTx) have a high incidence with inherent risks. Given the rise of obesity and subsequent bariatric surgery, there are new challenges for management, particularly in the setting of bypass anatomy, which is not well described. Trans-gastric remnant endoscopic retrograde cholangiopancreatography (TG-ERCP) is a novel technique that could evolve into a prim…
Open article record in new tab ↗In human laparoscopic hepatobiliary surgery, near-infrared fluorescence (NIRF) indocyanine green (ICG) is commonly employed for intraoperative cholangiography to delineate anatomical structures; however, it is not yet used in veterinary medicine. This is the first veterinary case of ICG cholangiography used to confirm common bile duct (CBD) patency in a dog with a ruptured gallbladder mucocele (GBM). A 10-year-old…
Open article record in new tab ↗A 23-year-old man presented with a life-threatening asthma exacerbation following a respiratory infection. Although he had a childhood history of asthma, he had remained asymptomatic in adulthood and reported regular use of both vapes and marijuana. His medical history included Type 2 Loeys-Dietz syndrome (LDS), requiring multiple vascular surgeries, rendering standard asthma therapies relatively contraindicated.…
Open article record in new tab ↗We describe the successful treatment of biliary duct obstruction (BDO) secondary to biliary carcinoma involving the bile duct, cystic duct, and intrahepatic ducts in two adult domestic shorthair cats using a novel technique. Both cats presented with marked hyperbilirubinemia, increased liver enzyme activities, and ultrasonographic evidence of BDO secondary to neoplasia. One cat previously had undergone cholecystod…
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