Readable research linked to original sources
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Browse normalized, publication-ready research with direct links to its evidence and source.
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Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
Loading articles data…
Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
33 articles
Newest firstIntroduction Recent studies show that young females now report higher e-cigarette use than males, reversing prior trends. While sex differences in use are documented, little is known about underlying risk profiles. This study applied a machine learning (ML) approach to identify and compare predictors of adolescent e-cigarette use by sex. Methods We analyzed cross-sectional data from 1829 9th graders in Southern Ca…
Open article record in new tab ↗Introduction Sexualized alcohol use (SAU) and sexualized drug use (SDU) involve the use of alcohol and/or drugs in sexual contexts, which may impact the HIV pre-exposure prophylaxis (PrEP) continuum of care. This study examines associations between SAU, SDU, and PrEP retention among Thai men who have sex with men (MSM), and explores the acceptability of mobile health interventions. Methods A quantitative study wit…
Objectives To examine next-day cognitive performance and subjective drug effects after smoking cannabis and to assess associations between performance and cannabinoid concentrations in blood and oral fluid. Methods In this observational study, healthy adults who regularly used cannabis (mean age 30 years; n = 65) smoked a legally purchased pre-rolled "joint" at night and were tested the next day, 12-15 h later. He…
Objective The current study aims to determine heterogenous latent profiles of substance use perceived harm and examine the concurrent associations between profiles and substance use experimentation. Methods We used data from the Adolescent Brain Cognitive DevelopmentSM Study (5.1 data release) 1-year follow up. Participants (N = 11184) were 52.2% male between the ages of 9 and 14 (M age = 10.48, SD = 0.65). Latent…
Introduction Cannabis use is proliferating among oncological populations. However, research is limited on whether cannabis routes and sources are associated with neighborhood disadvantage and whether it moderates the relationship between neighborhood disadvantage and patient-reported outcomes (PROs). This analysis evaluates the relationship between neighborhood disadvantage and cannabis source and route, and their…
Open article record in new tab ↗Adolescent substance use imposes lasting costs on education, mental health, and lifetime earnings, with early initiation strongly predicting adult dependence. Despite legal prohibition, approximately 21% of U.S. high school students report current alcohol use, 18% report current nicotine vaping, and 16% report current cannabis use. Social media plausibly contributes to these patterns, yet prior studies rely on bro…
Open article record in new tab ↗Objective Despite increased recreational cannabis legalization (RCL) in the US in recent years, little is known about cannabis advice received at prenatal care visits. We aimed to examine cannabis screening and counseling occurring at prenatal care visits, including adherence of advice to current clinical guidelines and variations by RCL status. Methods In this repeated cross-sectional study, we used 2017-2020 Pre…
Open article record in new tab ↗The expanding legalization of cannabis raises significant public health concerns about its use during pregnancy, particularly due to the limited understanding of its impact on neurodevelopment. Existing research suggests that perinatal cannabis or cannabinoid exposure may impair learning and memory; however, variations in study design hinder the ability to draw generalizable conclusions. Clinical studies are limit…
Open article record in new tab ↗Background Few studies have reported on the prevalence and health risks associated with substance use and substance use disorder (SU/SUD) in Veterans who use long-term opioid therapy (LTOT). We leveraged health record data to estimate SU/SUD prevalence and its association with mortality among Veterans on LTOT. Methods We conducted a secondary analysis of cohort data for Veterans on LTOT within Veterans Health Admi…
Open article record in new tab ↗Background Mental health clinicians are uniquely suited to support and provide important insights about substance use among pregnant patients. This mixed-methods study explored how mental health clinicians perceive and address prenatal cannabis use. Methods Participants were licensed mental health clinicians from Kaiser Permanente Northern California's Early Start perinatal substance use screening and counseling p…
Purpose Racism-based police violence (RPV) is an emerging public health concern. However, limited research has examined the relationship between RPV exposure and substance use, particularly among Black or African American and Hispanic emerging adults aged 18-29 years. This study assessed associations between lifetime RPV exposure across three domains (direct victimization, witnessing in person, and media-based exp…
Open article record in new tab ↗Background Rates of suicide mortality and substance use have increased globally. We updated and extended existing systematic reviews of the association between substance use and suicide. Methods This systematic review and meta-analysis explored the association between substance use and suicide mortality in peer reviewed, longitudinal cohort studies published from 2003 through 2024. Risk of bias was assessed using…
Open article record in new tab ↗Purpose This study investigated the effects of prenatal co-exposure to alcohol and synthetic cannabinoids on offspring viability, physical development, and neurobehavioral outcomes in young adulthood. The goal of this investigation was to determine whether prenatal co-exposure produced distinct outcomes from single-drug exposures, including sex-specific vulnerabilities in motor coordination and exploratory behavio…
Open article record in new tab ↗Introduction The Canadian Student Alcohol and Drugs Survey is a biennial, repeat cross-sectional survey of grade 7-12 students in the Canadian provinces. This study examined cannabis-related behaviours at five timepoints before and after legalization of cannabis for non-medical purposes. Methods Trends over time were examined using data from 2014-15 to 2023-24 (n = 264,558). Binary logistic regression examined cha…
Open article record in new tab ↗Objective The certainty of effects on neurodevelopmental outcomes resulting from perinatal cannabis exposure is yet to be established. This review synthesizes current clinical and preclinical evidence on neurodevelopment and related functional outcomes in offspring exposed to cannabis during pregnancy or early childhood. Additionally, gaps in the literature and suggestions to bridge these gaps are provided. Method…
Open article record in new tab ↗Experimental evaluation of cannabis tolerance has lacked an associative learning approach, focusing primarily on physiological variables. The present study assessed acute effects, chronic tolerance, and contextual specificity, exploring a potential associative component underlying cannabis tolerance. Sixteen adult Sprague-Dawley rats of both sexes were assigned to two groups, one receiving vaporized administration…
Physical Activity (PA) is important for mental, physical, and brain health. Adolescence is marked by increased engagement in risky substance use (SU) behaviors, which can negatively affect brain development. This study aims to determine if PA influences SU experimentation and initiation among adolescents. We predicted higher levels of PA would be associated with less SU, with a larger effect in more vigorous compa…
Open article record in new tab ↗Background While increasing numbers of parents use medical cannabis, little is known about their cannabis use or health, despite potential implications for child well-being. Recognizing that parenting is shaped by gendered roles and norms, this study compared mothers and fathers who use cannabis as medical cannabis patients. Methods Parents living with children (N = 372; 62.9 % mothers, 37.1 % fathers) were identi…
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