Readable research linked to original sources
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Browse normalized, publication-ready research with direct links to its evidence and source.
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Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
Loading articles data…
Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
17 articles
Newest firstStress exposure has increased significantly, contributing to higher rates of anxiety, depression, and post-traumatic stress disorder. However, individual responses to stress vary greatly, underscoring the concept of stress resilience. The acute stress response activates the amygdala, hippocampus, and prefrontal cortex, stimulating the HPA axis and triggering cortisol release, which typically restores balance throu…
Open article record in new tab ↗Despite substantial progress in preclinical cannabinoid research, translational studies on cannabis use disorders (CUD) are still insufficient due to the absence of robust, validated animal models that fully recapitulate the multifactorial clinical phenotype of human CUD. The complex nature of CUD and the incomplete understanding of its underlying neurobiological mechanisms contribute to the limited availability o…
BACKGROUND: Mental disorders are widely recognised as a major contributor to morbidity in prisons across the European Union, with evidence consistently indicating a markedly higher mental health burden among incarcerated individuals compared with community populations. Prison research has mainly focused on mental illness, often neglecting protective aspects of mental health from a salutogenic perspective. In Portu…
Open article record in new tab ↗Background Exposure to Adverse Childhood Experiences (ACEs) is associated with increased risk of substance use in women, including cannabis use during pregnancy. Less is known, however, about how resilience factors moderate the association of ACEs on cannabis use in early motherhood. Methods We used survey data from 126 predominately low-income and diverse mothers enrolled in a longitudinal study in the South Cent…
Open article record in new tab ↗Growing evidence suggests that psychedelic-assisted therapies can alleviate depression, anxiety, posttraumatic stress, and substance use disorder, offering relatively safe profiles, enhanced efficacy, and lasting effects after a few applications. Athletes often experience high levels of stress and pressure, making them susceptible to these psychiatric conditions. However, the effects of psychedelic substances on a…
Open article record in new tab ↗Medical students are at elevated risk for psychoactive substance use and mental health challenges due to academic pressures and environmental stressors. This study aimed to determine the prevalence and trends of psychoactive substance use among medical students at Riga Stradins University (RSU) and to examine associations with symptoms of anxiety, depression, and resilience to stress. A bilingual, anonymous cross-…
BackgroundWinter conditions intensify operational demands on healthcare services, particularly in community and rural settings where nurses often travel to deliver care. Environmental challenges, including hazardous road conditions and limited accessibility, can affect nurse well-being and patient safety. Few studies have explored how nurses personally experience and adapt to winter-related care delivery constrain…
Open article record in new tab ↗ObjectiveTo analyze the impacts of the COVID-19 pandemic on post-pandemic mental health, identifying the most prevalent symptoms, risk factors, and coping strategies. MethodsSystematic literature review conducted according to PRISMA guidelines, using open-access databases (Google Scholar and PubMed) with articles published between 2021 and 2025, in English or Portuguese, full-text available, and focused on human s…
Open article record in new tab ↗Background Several studies have reported that psychotic-like experiences are associated with low levels of resilience and increased suicide risk. However, it remains unknown as to whether resilience mediates or moderates the association between psychotic-like experiences and suicide risk. Therefore, in this study, we aimed to explore the moderating and mediating effect of resilience in the association between psyc…
Open article record in new tab ↗Chronic unpredictable and unavoidable stress is associated with mental health problems such as depression and anxiety, whereas cycles of stress and stress relief strengthen resilience. It has been suggested that increased breakdown of brain endocannabinoids (eCB) promotes a feeling of adversity. To assess the impact of stress on bioactive lipid homeostasis, we analyzed eCB, sphingolipids, and ceramides in seven br…
Open article record in new tab ↗The large-scale disruption to peoples’ daily lives during the COVID-19 pandemic provides a context for examining whether use of substances such as psychedelics in a naturalistic (outside of a controlled environment) setting, is associated with better mental wellbeing and resilience relative to those who use other drugs, or who do not use drugs at all. We interrogate data from the Great British Intelligence Test an…
Open article record in new tab ↗ABSTRACTBackground: Cancer is a life-threatening disease in Korean women. Female cancer patients in Korea have reported poor physical functioning and psychological distress after diagnosis. However, some patients experience post-traumatic growth (PTG), which includes positive feelings and changes.Objective: The main purpose of this study was to examine the relationships between PTG and its associated factors in Ko…
The COVID-19 pandemic has caused an unprecedented disruption to the lives of American Indian (AI) adolescents. While reservation-area AI youth already have a higher risk of substance use (SU) compared to their non-AI peers, COVID-19 stressors likely exacerbated this risk. However, COVID-19-specific and general resilience factors may have buffered against increased SU over the course of the pandemic. Using a person…
Open article record in new tab ↗Studies investigating the psychosomatic effects of social isolation in animals have shown that one of the physiologic system that gets disrupted by this environment-affective change is the Endocannabinoid System. As the levels of endocannabinoids change in limbic areas and prefrontal cortex during stressful times, so is the subject more prone to fearful and negative thoughts and aggressive behavior. The interplay…
Open article record in new tab ↗BACKGROUND: Although periods of HIV antiretroviral therapy (ART) discontinuation have deleterious health effects, ART is not always sustained. Yet, little is known about factors that contribute to such ART non-persistence among long-term HIV survivors. The present study applied a convergent parallel mixed-methods design to explore the phenomena of stopping/starting and sustaining ART, focusing on low-socioeconomic…
BACKGROUND: Pharmacological neuroenhancement (PNE) refers to the use of psychoactive substances without doctor's prescription to enhance cognitive performance or to improve mood. Although some studies have reported that drugs for PNE are also being used to cope with stressful life situations, nothing is known about the relationship of PNE and resilience, i.e. the ability to recover from stress. This study aimed at…