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Browse normalized, publication-ready research with direct links to its evidence and source.
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Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
Loading articles data…
Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
16 articles
Newest firstBackground Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline and frequently co-occurs with chronic pain. Worldwide, over 55 million people are affected by AD, with nearly half experiencing persistent pain. Chronic pain has been linked to accelerated memory deterioration and an increased risk of dementia, but the interplay between these conditions remains poorly…
Open article record in new tab ↗Alzheimer's disease (AD) is primarily recognized for progressive cognitive decline driven by beta-amyloid accumulation and tau pathology. However, many individuals with AD also experience chronic pain and depressive symptoms, which significantly impair daily functioning and quality of life and increase caregiver burden. These non-cognitive features are frequently underrecognized, despite evidence suggesting they s…
Peripheral artery disease (PAD) is a progressive vascular disease characterized by atherosclerotic narrowing of peripheral arteries, resulting in decreased blood flow to the extremities. Common risk factors for PAD are diabetes, hypertension, and hyperlipidemia, although it can also occur in patients without these comorbidities, such as in the use of marijuana or alcohol. Recent research suggests that marijuana an…
Open article record in new tab ↗The evolving legal landscape has increased marijuana accessibility across the United States, including for medical use to manage clinical symptoms among people with HIV. The effects of marijuana use remain understudied in youth with HIV (YWH), who face lifelong antiretroviral therapy (ART) and an elevated risk of developing comorbidities. This study applied a multi-modal approach, including plasma biomarker analys…
Open article record in new tab ↗Malnutrition in old age is a serious worldwide health concern, with complicated relationships between socioeconomic, health, and physiological factors. This research examines the influence of socioeconomic status, comorbidities, and sociodemographic factors on the nutritional status of older people in Bangladesh. The aim of this study is to evaluate the effect of factors like age, gender, education, income, marita…
With increasing life expectancy, the prevalence of cardiovascular disease (CVD) accompanied by comorbidities is rising, presenting a growing challenge for healthcare systems. Understanding shared genetic factors underlying CVD and its comorbidities can help develop more effective prevention and treatment strategies. In this study, we investigated genetic correlations between CVD and common comorbidities using geno…
Open article record in new tab ↗BackgroundThis study investigates the determinants of quality of life (QoL) among older adults residing in institutional settings in Bangladesh. MethodsUtilizing a cross-sectional design, data were collected from 570 elderly participants across four institutional care facilities. Sociodemographic, physical health, dietary habits and comorbidity determinants were analyzed to determine their effect on QoL, measured…
Open article record in new tab ↗This study aims to investigate the clinical course and factors associated with hospital admission and mortality among SARS-CoV-2 patients within the Nairobi Metropolitan Area. The study utilizes a multicenter retrospective cohort design, collecting clinical characteristics and laboratory parameters of hospitalized patients from March 2020 to May 2022. Data analysis includes percentages, frequencies, chi-square tes…
Open article record in new tab ↗IntroductionOur primary purpose is to understand comorbidities and health outcomes associated with electronic nicotine delivery systems (ENDS) use.MethodsStudy participants were Kaiser Permanente (KP) members from eight US regions who joined the Kaiser Permanente Research Bank (KPRB) from September 2015 through December 2019 and completed a questionnaire assessing demographic and behavioral factors, including ENDS…
Open article record in new tab ↗Background Approximately 3.8% of adults worldwide have used cannabis in the past year. Understanding how cannabis use is associated with other health conditions is crucial for healthcare providers seeking to understand the needs of their patients, and for health policymakers. This paper analyzes the relationship between documented cannabis use disorders (CUD), cannabis use (CU) and other health diagnoses among pri…
ObjectivesTo explore clustering of comorbidities among patients with a new diagnosis of osteoarthritis (OA) and estimate the 10-year mortality risk for each identified cluster. MethodsThis is a population-based cohort study of individuals with first incident diagnosis of OA of the hip, knee, ankle/foot, wrist/hand, or unspecified site between 2006 and 2020, using SIDIAP (a primary care database representative from…
Open article record in new tab ↗INTRODUCTION: People living with HIV (PLHIV) who use illicit drugs (other than or in addition to cannabis) are living longer due to antiretroviral therapy (ART). Older PLHIV who use drugs have an increased risk for comorbidities, and managing multiple health conditions is a growing concern among this population. However, in-depth understandings of the lived realities and complexities of living with HIV alongside c…
Open article record in new tab ↗BACKGROUND: Continuous use of amphetamines, alcohol, benzodiazepines, cannabis, cocaine, or opioids contributes to health impairments, increased morbidity, and overdose deaths among patients with substance use disorders (SUDs). This study evaluates the impact of inpatient detoxification, injecting substance use, age, and gender on substance use over time among patients undergoing outpatient SUD treatment. METHODS:…
BackgroundThe study aimed to analyze the demographic, comorbidities, biomarkers, pharmacotherapy, and ICU-stay with the mortality outcome of COVID-19 patients admitted in the intensive care unit of a tertiary care hospital in a low-middle income country, Bangladesh. MethodsThe retrospective cohort study was done in Holy Family Red Crescent Medical College Hospital from May to September 2020. All 112 patients who w…
Open article record in new tab ↗BACKGROUND: No study has examined the prevalence of tobacco, other substance use, and symptoms of anxiety and depression, and rates of comorbidities among the orthopaedic trauma population, despite the impact they have on recovery from surgery. This study aims to 1) describe the rates of symptoms and substance use; 2) compare rates of symptoms and substance use among smokers versus non-smokers; and 3) examine the…
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