Readable research linked to original sources
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Browse normalized, publication-ready research with direct links to its evidence and source.
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Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
Loading articles data…
Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
23 articles
Newest firstBackground: Patient safety learning systems operate primarily at the national level, yet the potential for international sharing of safety intelligence remains largely unrealised. Other safety-critical industries, including civil aviation, nuclear power, and rail, have developed international incident reporting and learning systems whose design principles may offer transferable insights for healthcare. Objective:…
Open article record in new tab ↗BackgroundPatient safety remains a global priority, yet adverse events persist due to gaps in communication, information, training and safety culture. Rapid response systems standardise observation models are widely used to recognise deterioration and guide escalation and response for ward patients in hospitals. A notable gap concerns the role of planning for further care, can improve hospital resource prioritisat…
BackgroundSouth Africas public healthcare system serves most of the population through approximately 3,900 primary healthcare clinics characterised by long waiting times and high volumes of repeat-prescription visits. No published pre-arrival digital triage system operates across all 11 official South African languages while aligning with the South African Triage Scale (SATS). This paper reports the design and pre…
Open article record in new tab ↗BackgroundDespite widespread recognition that patient safety learning can transcend national boundaries, no international patient safety learning system (PSLS) currently exists. There is no expert consensus on the purpose, key requirements, or feasibility of such a system. ObjectiveTo gain consensus from an international panel of healthcare experts regarding the key requirements and feasibility of a potential inte…
Open article record in new tab ↗BackgroundIn the world of Artificial Intelligence (AI), Generative Pretrained Transformer-3 (GPT-3), has gained significant popularity for its demonstrated potential in medical education and diagnostics. RationaleWhile AI has shown promising results in healthcare thus far, its understanding of ocular urgencies, particularly uveitis, demands a focused investigation. MethodsThis study explored the application of Cha…
Open article record in new tab ↗ImportanceEmerging evidence suggests healthcare AI systems may exhibit deceptive alignment (appearing safe during validation while optimizing for misaligned objectives in deployment) and evaluation awareness (detecting and adapting behavior during audits), undermining regulatory validation frameworks. ObjectiveTo quantify the performance of multi-layer red-teaming approaches in detecting sophisticated healthcare A…
Open article record in new tab ↗Background "Natural products" (NPs), including dietary supplements, are widely used, yet little is known about NP use for chronic pain and related conditions. Objective To develop a new NP survey to better understand reasons for NP use, beliefs, concerns, medication substitution, and provider disclosure. Methods Based on similar surveys and input from veteran focus groups and subject matter experts, a new brief NP…
Background: Agitation is a frequent and challenging symptom in schizophrenia and bipolar disorder, characterized by heightened motor activity, emotional distress, and potential aggression. This symptom is most observed during acute episodes, representing a significant burden on patients, caregivers, and healthcare systems. Agitation is a leading cause of emergency department visits and psychiatric hospitalizations…
Open article record in new tab ↗Introduction: Cannabidiol (CBD) is widely available over the counter for presumed medical and recreational purposes. Despite its non-psychoactive nature, CBD exhibits intrinsic pharmacological activity that may lead to potential adverse drug events (ADEs) and drug-drug interactions (DDI) with common prescription medications through cytochrome P450 inhibition. Due to their largely unregulated nature and widespread…
BackgroundWinter conditions intensify operational demands on healthcare services, particularly in community and rural settings where nurses often travel to deliver care. Environmental challenges, including hazardous road conditions and limited accessibility, can affect nurse well-being and patient safety. Few studies have explored how nurses personally experience and adapt to winter-related care delivery constrain…
Open article record in new tab ↗BackgroundThe inadequate design of work procedures is often cited as a contributory factor in patient safety incidents globally, indicating a potential learning need for healthcare teams. Further, the recent COVID-19 pandemic has necessarily witnessed a proliferation of new and re-designed work procedures introduced as staff adapted to altered working conditions, work environments and expanded job roles. In respon…
Open article record in new tab ↗BackgroundHuman error is a leading cause of preventable harm in clinical care, driven by factors such as cognitive overload and staff turnover. While customisable digital cognitive aids (cDCAs) have emerged as real-time protocol-tailored support, a framework to quantify their total impact on human error and its fundamental limits has been lacking. MethodsWe conducted a pooled analysis of five randomised high-fidel…
BackgroundThe deployment of artificial intelligence (AI) in healthcare necessitates robust safety validation frameworks, particularly for systems directly interacting with patients. While theoretical frameworks exist, there remains a critical gap between abstract principles and practical implementation. Traditional LLM benchmarking approaches provide very limited output coverage and are insufficient for healthcare…
Open article record in new tab ↗BackgroundDiagnostic errors in healthcare pose substantial risks, leading to increased costs, patient anxiety, and delayed diagnoses. Despite its prevalence, diagnostic errors have historically received less attention compared to other medical errors, necessitating urgent action to address these critical issues. This is more so in the low- and middle-income countries. (LMICs). This study aimed to analyze patterns…
Open article record in new tab ↗Introduction The increasing popularity of cannabinoids for treating numerous neurological disorders has been reported in various countries. Although it reduces tetrahydrocannabinol psychoactivity, it helps patients tolerate higher doses and complements the anti-spasmodic effects of tetrahydrocannabinol. One of the most important potential of cannabinoids are related to its potential to help children with cerebral…
Introduction The use of medical cannabis in pediatrics is not common in clinical practice, and there is a lack of prospective studies, especially in pediatric subpopulations. This study aimed to provide data on the off-label administration of tetrahydrocannabinol (∆9-THC) in a pediatric tertiary center in Austria. Methods A retrospective data analysis was performed to assess the use of ∆9-THC at the Department of…
Open article record in new tab ↗BackgroundTrends of opioid prescribing in the NHS has been well published, yet trends for the same in private prescribing have not been widely established. AimTo assess trends and geographical variation of controlled opioids prescribed by private prescribers in England. Design and settingA retrospective observational study in English primary healthcare. MethodsData on Schedule 2 and 3 controlled opioids ("controll…
Open article record in new tab ↗BackgroundAutism is a normal part of cognitive diversity, resulting in communication and sensory processing differences, which can become disabling in a neurotypical world. Autistic people have an increased likelihood of physical and mental co-occurring conditions and die earlier than neurotypical peers. Inaccessible healthcare may contribute to this. Autism Health Passports (AHPs) are paper-based or digital tools…
Open article record in new tab ↗BackgroundWith the onset of COVID-19, general practitioners (GPs) and patients worldwide swiftly transitioned from face-to-face to digital remote consultations. There is a need to evaluate how this global shift has impacted patient care, healthcare providers, patient and carer experience, and health systems. ObjectiveWe explored GPs perspectives on the main benefits and challenges of using digital remote care. Met…
Open article record in new tab ↗Background and aims Utilization and safety of cannabidiol (CBD) in patients with autoimmune hepatitis (AIH) are currently unknown. We aimed to identify the frequency of CBD use, impact on symptoms, and safety profile. Methods An invitation to complete a CBD-specific questionnaire was posted every other day to well-established autoimmune hepatitis Facebook communities (combined membership of 2600 individuals) durin…
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