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Brief Report 2025CC BYFree full text

Network analysis of Alcohol, Smoking and Substance Involvement Screening Test (ASSIST) 3.1 items for non-medical use of alcohol, tobacco, cannabis, prescription sedatives, prescription stimulants, and prescription opioids.

Dvora Shmulewitz, Maor Daniel Levitin, Roi Eliashar, Mario Mikulincer, Shaul Lev-Ran

Background At-risk substance use is a leading cause of preventable morbidity and mortality worldwide. The Alcohol, Smoking and Substance Involvement Screening Test 3.1 (ASSIST) is widely used to screen for such use. Objectives Using network analysis to reframe risky substance use as a web of interacting ASSIST symptoms to provide important suggestions about potential mechanisms underlying risky use. Methods Cross-…

Frontiers in Psychiatry Europe PMC

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Research Article 2025CC BYFree full text

Prevalence of Cannabidiol (CBD) Use Among Patients Taking Medications with Known Drug-Drug Interactions: A Cross-Sectional Analysis.

Hunter Geneau, Michael Kovasala, Grant Brown, Simeon Holmes, Olivia Hime, Michael McNally +3 more

Introduction: Cannabidiol (CBD) is widely available over the counter for presumed medical and recreational purposes. Despite its non-psychoactive nature, CBD exhibits intrinsic pharmacological activity that may lead to potential adverse drug events (ADEs) and drug-drug interactions (DDI) with common prescription medications through cytochrome P450 inhibition. Due to their largely unregulated nature and widespread…

Journal of Clinical Medicine