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Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
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Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
2,010 articles
Newest firstCannabis use can have detrimental effects on adolescents' mental health, often co-occurring with child and adolescent psychiatric disorders (CAPD). This study assessed diagnostic prevalence trends in cannabis-related disorders and co-occurring diagnosed CAPD in adolescents receiving outpatient treatment in Germany. Outpatient claims data from the national public health insurance system, covering almost 4 million c…
Open article record in new tab ↗Background and hypothesis A sex difference in the clinical presentation of schizophrenia is well known. Males have on average an earlier symptom onset, worse functional capacity, and more negative symptoms. Studies on the neurobiological correlates of psychosis show that brain endocannabinoid system (ECS) is dysregulated in male patients with first-episode psychosis (FEP). We now evaluated whether the brain ECS is…
Significance Flavor accessories (e.g., flavor capsules), which are separate products that can be used with combustible tobacco products to alter their flavor, are on the market. These new products may bypass flavor restrictions and appeal to youth, yet no research has examined US youth awareness or use of flavor accessories. This study aimed to examine awareness and use of flavor accessories among a sample of yout…
Objective The objective of this study was to examine whether cannabis exposure calls to the British Columbia Drug and Poison Information Centre (DPIC) were impacted by the legalization of non-medical cannabis in Canada. Methods We fit interrupted time series models to monthly counts of cannabis cases from 2013 to 2021, stratified by age and cannabis form. We set the intervention month to October 2018 legalization…
This study examined the prevalence and patterns of polydrug use among a national sample of civilians aged 12 years or older, with a focus on polydrug use involving opioids, assessing the influence of the first drug used on these behaviors. Using 2020 National Survey on Drug Use and Health (NSDUH) data, five mutually exclusive drug groups were identified in a hierarchical order: opioid use, stimulant or psychoactiv…
Purpose This study used data from the National Health and Nutrition Examination Survey (NHANES) to examine associations between the use of four illicit drugs (cocaine, heroin, marijuana, and methamphetamine) and the dental caries experience among adults in the US using the Decayed, Missing and Filled Teeth (DMFT) index. Materials and methods Data from NHANES 2017-2018, a cross-sectional study that included adults…
Dyadic coping among sexual minority men (SMM) has been a focus of HIV prevention research for decades, but few studies have examined relationship quality as a covariate of HIV care cascade outcomes (ART adherence and an undetectable viral load (VL)). This study utilized a 5-category relationship status variable (single; non-monogamous, sero-discordant; non-monogamous, sero-concordant; monogamous, sero-discordant;…
Open article record in new tab ↗Introduction and aims Cannabis use among university students is a growing concern, particularly in demanding medical programs. We estimated prevalence, identified predictors, and compared coping strategies among medical students in Uganda. Design and methods Cross-sectional survey of 318 undergraduates at Kampala International University (Western Campus). Cannabis use and hazardous/disordered use were screened wit…
Objective To evaluate trends in CHS hospitalizations in Canada, including their frequency and individual characteristics. Methods This study utilized data from the Canadian Institute for Health Information's Discharge Abstract Database to perform descriptive data analysis and employed JoinPoint Trend Analysis Software to analyze annual percent change (APC) and average annual percent change (AAPC) in hospitalizatio…
Open article record in new tab ↗Purpose Nicotine and cannabis are commonly co-used among adolescents and young adults (AYAs). Same session co-use has more negative effects than co-use that does not overlap. Little is known about how or why these products are used within the same session. Enhanced understanding of this behavior pattern can be leveraged to reduce co-use in this population. Methods Connecticut AYAs (15-20 years old) who self-report…
Open article record in new tab ↗Objective Xerostomia (dry mouth) is a common condition that negatively impacts life quality for adults of all ages. Yet, xerostomia has primarily been studied among older adults and populations at high risk of dry mouth, with no widely-available self-reported instrument to assess xerostomia accurately among younger populations. This study aimed to develop a brief xerostomia assessment tool specifically designed fo…
Open article record in new tab ↗Although random assignment is the standard for drawing causal inferences within clinical trials, it is generally precluded in legal market cannabis research given its federal classification as a schedule 1 drug. Unfortunately, this may cause selection bias and compromise internal validity, and thus, alternative approaches are necessary. One such approach in this context, as well as more broadly, is quasi-random as…
Open article record in new tab ↗Novel psychoactive substances (NPSs) exhibit extremely strong pharmaco-toxicological activity, often leading to severe adverse effects that pose a serious risk to consumers' health. Among these, synthetic cannabinoids (SCs) currently represent the majority of drug seizures in Europe. One such compound, AKB-48 (also known as APINACA), was first identified in Japanese herbal smoking blends in 2012. Although it mimic…
Pain is prevalent among people with HIV (PWH), and many PWH who experience pain also use substances (illicit drug and/or unhealthy alcohol use). While cocaine use and cocaine and alcohol co-use are prevalent in this population, their effects on pain in PWH are unknown. This study aims to investigate the association of cocaine use and co-use of cocaine and alcohol with pain interference among PWH. We completed a se…
Open article record in new tab ↗Background Educational attainment (EA), which comprises cognitive (CogEA) and noncognitive (NonCogEA) components, is positively genetically correlated with alcohol and cannabis use but negatively correlated with alcohol and cannabis use disorders (AUD and CUD). These paradoxical associations suggest that shared genetic influences with EA may differ by level of substance involvement. Methods To test this, we examin…
Aim This study aimed to investigate the association between cannabis use prior to enrollment in a First Episode Psychosis (FEP) program and prognosis, including severity of psychiatric symptoms, type of antipsychotic treatment prescribed, and clinical recovery. Methods A longitudinal cohort study was conducted on patients aged 18-35 diagnosed with affective and non-affective psychosis who were referred to the FEP…
Background Predicting progression from substance use to substance use disorder (SUD) is challenging, particularly for participants with cannabis and stimulant use who follow distinct risk trajectories. Machine learning enables integration of demographic, behavioral, wearable-derived, and social determinants of health (SDoH) data, yet few studies have compared linear and non-linear approaches in large, diverse popu…
Open article record in new tab ↗Introduction The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), continues to pose major health challenges despite effective vaccination efforts. The sustained occurrence of breakthrough infections and emerging variants of the virus highlights the need for additional therapeutic strategies. Given the anti-inflammatory role of the cannabinoid typ…
Introduction Washington state's adult use cannabis market operates under regulations by the Washington State Liquor and Cannabis Board to restrict access and promotion among young people. Cannabis edibles sold in the state are required to contain specific labels that inform consumers that the product contains cannabis and provide contact information for Poison Control. However, it is unclear how teens perceive suc…
INTRODUCTION: Preoperative substance use is increasingly observed among candidates for metabolic and bariatric surgery (MBS), yet its perioperative and 1-year effects remain unclear in the Middle East and North Africa (MENA). We assessed whether routine preoperative urine toxicology screening tests (TSTs) predict anesthetic requirements, recovery, early complications, and 1-year weight loss. METHODS: Prospective s…