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Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
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Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
11 articles
Newest firstBACKGROUND: Laparoscopic cholecystectomy is associated with the risk of iatrogenic biliary structure injury. Therefore, indocyanine green fluorescence dye is used to provide better visualization of the different biliary structures to avoid this type of injury. However, there is still a debate regarding the best route of ICG administration—either intrabiliary or intravenous. This meta-analysis aims to compare the t…
Open article record in new tab ↗Background Fluorescence cholangiography (FC) with indocyanine green (ICG) enables real-time intraoperative visualization of extrahepatic biliary anatomy during laparoscopic cholecystectomy (LC). There is no consensus on the optimal ICG dose or timing of administration for LC. The goal of this study was to implement a simple intraoperative low-dose ("microdose") ICG protocol that facilitates non-inferior biliary vi…
Background Bile duct injury (BDI) is a morbid complication of laparoscopic cholecystectomy due to poor recognition of the anatomy and inadequate visualization of the extra-hepatic biliary ducts. Near-infrared indocyanine green (ICG) is the most commonly used non-invasive option to assist with identification of the extra-hepatic biliary structures. However ICG is limited by its slow onset of action and lack of spec…
In human laparoscopic hepatobiliary surgery, near-infrared fluorescence (NIRF) indocyanine green (ICG) is commonly employed for intraoperative cholangiography to delineate anatomical structures; however, it is not yet used in veterinary medicine. This is the first veterinary case of ICG cholangiography used to confirm common bile duct (CBD) patency in a dog with a ruptured gallbladder mucocele (GBM). A 10-year-old…
Open article record in new tab ↗Background This study investigated the clinical application of the indocyanine green (ICG) fluorescence navigation technique in bile duct identification during laparoscopic common bile duct exploration (LCBDE) for complex hepatolithiasis. Methods Eighty patients with complex hepatolithiasis were admitted to our department between January 2022 and June 2023 and randomly divided into control and observation groups.…
Introduction Stump cholecystitis is managed by performing a completion cholecystectomy, which can be done either laparoscopically or by an open method. The use of indocyanine green (ICG) is known to improve the identification of the biliary tree anatomy, facilitating Calot's triangle dissection and shortening surgery, thereby reducing the risk of bile duct injuries and making laparoscopic cholecystectomy safer. Pa…
Open article record in new tab ↗Background The treatment of common bile duct (CBD) stones with minimally invasive surgery (MIS) is more technical demanding than laparoscopic cholecystectomy (LC), especially in patients with history of previous abdominal surgery, cholangitis or cholecystitis. Near-infrared (NIR) cholangiography via systemic or biliary tree administration of indocyanine green (ICG), which enhances the visualization of the biliary…
Background Laparoscopic choledocholithotomy for a large impacted common bile duct (CBD) stone is a challenging procedure because of the technical difficulty and the possibility of postoperative complications, even in this era of minimally invasive surgery. Herein, we present a case of large impacted CBD stones. Case summary A 71-year-old man showed a distal CBD stone (45 mm × 20 mm) and a middle CBD stone (20 mm ×…
Open article record in new tab ↗Over the last decade fluorescence-guided surgery has been primarily focused on the NIR-I window. However, the NIR-I window has constraints, such as limited penetration and scattering. Consequently, exploring the performance of NIR-I dyes at longer wavelengths (i.e., the NIR-II window) is crucial to expanding its application. Two fluorophores were used in three pigs to identify the mean fluorescence intensity (MFI)…
Background The dose and dosing time of indocyanine green (ICG) vary among fluorescence cholangiography (FC) studies. The purpose of this prospective, randomized, exploratory clinical trial was to optimize the dose and dosing time of ICG. Methods PubMed was searched to determine the optimal dose. To optimize the dosing time of ICG, a clinical trial was designed with two parts. The first part included patients with…
Background Indocyanine green clearance test (ICG-K) has been shown as a sensitive marker of liver function in patients with cirrhosis. However, its role in the assessment of liver function in children with biliary atresia is not well established. The present study was undertaken to evaluate the ICG-K in an experimental model of cholangitis and partial biliary obstruction. Materials and methods Thirty albino rats w…
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