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Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
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Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
51 articles
Newest firstAccidental exposure to edible cannabis products in children is an increasing public health concern. The clinical presentation is often nonspecific, which can delay diagnosis and lead to inappropriate management. Toxicological screening is therefore essential for accurate diagnosis and appropriate treatment. We report the toxicokinetic (TK) profiles of delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) follow…
Open article record in new tab ↗This narrative review synthesizes the toxicological, clinical and medico-legal aspects of paediatric cannabis intoxication. By providing a comprehensive overview, it aims to inform future research, guide policymaking, and enhance clinical and toxicological practice in addressing this growing public health concern. The pharmacokinetics of cannabinoid ingestion in children are significantly influenced by the immatur…
Open article record in new tab ↗Background/Objectives: Symptoms from cancer and treatments often cause pediatric patients and their families to seek complementary and integrative medicine (IM) for relief. The aim of this study was to better describe the characteristics of pediatric patients at a tertiary cancer center who utilize an IM consultative service in the outpatient setting and the associated discussions with a pediatric-focused IM physi…
Open article record in new tab ↗Background Sexual and gender minority (SGM) youth are at elevated risk for adverse mental health and substance use outcomes. Stressors such as family conflict, discrimination, and trauma have been suggested as possible mediators of these disparities. Aims This study examined whether family conflict, discrimination, and trauma mediate the associations between SGM identity and adverse outcomes, including suicide att…
Introduction Cannabis-based medicine (CBM) is recommended for the treatment of tics in otherwise treatment-resistant adult patients with Tourette syndrome (TS). However, evidence in children with TS is very limited. Long-term effects of CBM in this population are unknown. Case presentations We present two cases of long-term follow-up over six and five years, respectively, in male adolescents with TS who were admin…
Open article record in new tab ↗Objective To analyze etiologies and management of postoperative intestinal obstruction following surgery (exeision of the dilated bile duet and Roux-enY hepaticojejunostomy) for congenital biliary dilatation (CBD) in children. Methods A single-institution retrospective review was conducted on 475 patients who underwent Roux-en-Y hepaticojejunostomy following complete excision of the dilated bile duct. Among the co…
Open article record in new tab ↗Objectives The prevalence of alcohol use among adolescents in Croatia is high. The aim of this study was to determine the age and circumstances of first alcohol and drug consumption among adolescents. Methods An online questionnaire survey was conducted among final-year high school students in Split-Dalmatia County, Croatia, between June 6 and December 28, 2020. Statistical analyses were performed using chi-square…
Open article record in new tab ↗BackgroundChild mental health is a critical public health concern in the United States. This study examines the multifaceted determinants of child mental health, including demographic, socioeconomic, family, healthcare access, and chronic health condition information. MethodsThis study utilized data from the National Survey of Childrens Health (NSCH). Univariate, bivariate, and multivariable logistic regression mo…
Open article record in new tab ↗BackgroundWhen receiving an attention deficit hyperactivity disorder (ADHD) diagnosis, children and families/carers need clear and accurate information about the condition in a suitable format. However, many of the available resources are complex or provide content that is not evidence-based. Furthermore, there are limited studies that co-develop digital resources with and for children, particularly those with ADH…
Open article record in new tab ↗BackgroundArboviruses like Yellow Fever Virus (YFV), Dengue Virus (DENV), Chikungunya Virus (CHIKV), and West Nile Virus (WNV) frequently cause outbreaks in sub-Saharan Africa. Identifying risk factors in children can improve diagnosis, treatment, and prevention strategies. This study identified factors associated with seropositivity to YFV, DENV, CHIKV and WNV among children in Teso South Sub-County, Western Keny…
Open article record in new tab ↗BackgroundLeptospirosis is an emerging zoonotic disease with high incidence in tropical regions such as the Peruvian Amazon. Although it affects individuals of all ages, knowledge about its clinical and epidemiological behavior in children under five years old remains limited. This population may present atypical clinical forms, nonspecific symptoms, and a milder course, increasing the risk of underdiagnosis and d…
IntroductionIn September 2023, mpox clade 1b emerged in Kamituga, a mining zone in South Kivu, DR Congo, primarily through sexual transmission. This study investigates an mpox clade 1b outbreak in Uvira, 300 km from Kamituga, where the first case was reported in May 2024. MethodsFrom June-October 2024, clinical and household data from suspected mpox cases were collected at Uvira hospital and through investigations…
Open article record in new tab ↗BackgroundAcute gastroenteritis (AGE) causes substantial morbidity and mortality in children <5 years old accounting for 9 million hospitalizations. Prolonged hospitalization can cause dire consequences to the patient and healthcare system. However, data on factors associated with prolonged hospitalization for AGE in developing countries are limited. ObjectivesWe aim to describe trends and assess factors associate…
Open article record in new tab ↗Introduction Medical cannabis treatment for autistic children has recently become popular, and studies have focused on examining the treatment's effects on children's symptom presentation, reported side effects, and dropout rates. However, no previous study has investigated the factors influencing adherence and dropout rates in cannabis treatment. Method This explanatory sequential mixed-methods study explored the…
Open article record in new tab ↗Children between the ages of one and 18 are at a heightened risk of death and impairment due to traumatic brain injury (TBI). TBI can be deadly and is usually categorized as mild, moderate, or severe according to the Glasgow Coma Scale (GCS). For individuals with a TBI and an abnormal GCS, the preferred modality is non-contrast CT of the head. This review focuses on the medical treatment and rehabilitation of chil…
Open article record in new tab ↗Purpose This study aimed to investigate the effects of low frequency (LF) pitch perception on speech-in-noise and music perception performance by children with cochlear implants (CIC) and typical hearing (THC). Moreover, the relationships between speech-in-noise and music perception as well as the effects of demographic and audiological factors on present research outcomes were studied. Methods The sample consiste…
Background/objectives Patients with life-limiting conditions (LLCs) often suffer from restlessness, spasticity, pain, and seizures. Dronabinol (DRB) may have a relieving effect; however, data on the effectiveness of DRB in children with LLCs are limited to outpatients. The aim of this study was to assess the efficacy and safety of DRB. Methods Retrospective analysis of inpatients. Results From 2011 to 2021, 1219 p…
Open article record in new tab ↗Introduction The association between Δ8-tetrahydrocannabinol (THC) and cardiac dysrhythmia has not been well described in children. Asystole, while consistent with reports of severe bradycardia and apnea in children, is uncommonly described in the current literature. We present the first pediatric case of asystole and apnea following THC ingestion. Case A 7-year-old male presented to the emergency department (ED)…
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