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Browse normalized, publication-ready research with direct links to its evidence and source.
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Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
Loading articles data…
Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
21 articles
Newest firstBackground Maturity-onset diabetes of the young (MODY) is a rare monogenic diabetes with significant renal risk, especially when combined with hyperglycemia, obesity, and other factors. While chronic cannabis use may further accelerate kidney decline, no previous reports have described rapid progression to ESRD in a young patient with MODY, obesity, hypertension, and cannabinoid hyperemesis, as presented here. Cas…
Open article record in new tab ↗Background Most studies related to at-risk foot are based on databases, cohorts, hospitalized patients, or outpatient studies, lacking comprehensive data on risk factors. According to the latest Diabetic foot risk stratification system, there is currently a lack of research or descriptions of the diabetic at-risk foot population. Aims This study aims to investigate the prevalence, characteristics, and influencing…
Open article record in new tab ↗Background and purpose Common bile duct stones (CBDS) are a common disease. Endoscopic retrograde cholangiopancreatography (ERCP) is currently recognized as the preferred treatment method for CBDS. However, there are cases that cannot be removed through ERCP. Therefore, the aim of this study is to explore the value of magnetic resonance cholangiopancreatography (MRCP) in assessing the success of CBDS removal throu…
Open article record in new tab ↗Clip migration into the common bile duct (CBD) represents a rare yet severe complication after laparoscopic biliary surgery. Herein, we report a case of a 75-year-old male patient who previously received simultaneous laparoscopic cholecystectomy (LC) and laparoscopic common bile duct exploration (LCBDE) with T-tube drainage. The patient was admitted with upper abdominal pain and jaundice. Elevated inflammatory ind…
Open article record in new tab ↗Purpose This study aimed to construct and compare machine learning models for predicting recurrent extrahepatic bile duct stones after common bile duct exploration and to clarify the contribution of key risk factors using SHAP analysis, thereby providing a reliable tool for clinical risk assessment and intervention. Methods Retrospective analysis of 1,363 patients (2010-2024, Huangshi Central Hospital/Honghu Peopl…
Open article record in new tab ↗Within the last decade the role of the endocannabinoid system (ECS) has been a significant part of ophthalmic research, including both ocular physiology and the development of eye pathologies. It is known that this widespread cell-signaling system is involved in retinal neurobiological processes, including visual signal processing, as well as neurotransmission. Furthermore, various research indicated the involveme…
Open article record in new tab ↗Cannabis compounds are well-known for their therapeutic applications in the treatment of various health issues. These substances, mainly cannabinoids, are known for their antimicrobial properties and ability to interact with various cells through endocannabinoid receptors. However, the limitations of cannabis extract, particularly its viscosity, stickiness, and low bioavailability when applied topically, limit its…
Open article record in new tab ↗Essential oils have emerged as popular natural alternatives to synthetic ingredients in cosmetic products, drawing attention for their therapeutic potential in treating skin conditions like acne, psoriasis, and atopic dermatitis. This systematic review analyzed 70 studies from the past decade across multiple databases to evaluate their effectiveness and safety in derma cosmetic applications. The research encompass…
Open article record in new tab ↗Background The prevalence of sexually transmitted infections (STIs) remains alarming, especially among young people and college students, highlighting the vulnerability of this population. In the academic context, it is worth investigating whether medical students, despite their access to information, also engage in risky sexual behaviors. Objective The present study aims to describe the sexual behavior of Brazili…
Background Pulmonary arterial hypertension occurs as a result of vascular remodeling and dysregulation of endothelial cells that narrows small pulmonary arteries and raises precapillary pressures. Pulmonary arterial hypertension is a rare and progressive disease characterized by dyspnea, chest pain, and syncope. Parenteral treprostinil is indicated for the treatment of pulmonary arterial hypertension to diminish s…
Open article record in new tab ↗Background Tai Chi (TC) controls pain through mind-body exercise and appears to alter inflammatory mediators. TC actions on lipid biomarkers associated with inflammation and brain neural networks in women with knee osteoarthritic pain were investigated. Methods A single-center, pre- and post-TC group (baseline and 8 wk) exercise pilot study in postmenopausal women with knee osteoarthritic pain was performed. 12 el…
The rise of antimicrobial resistance is a global public health crisis that threatens the effective control and prevention of infections. Due to the emergence of pandrug-resistant bacteria, most antibiotics have lost their efficacy. Bacteriophages or their components are known to target bacterial cell walls, cell membranes, and lipopolysaccharides (LPS) and hydrolyze them. Bacteriophages being the natural predators…
Open article record in new tab ↗BackgroundPatients with hypermobile Ehlers–Danlos Syndrome (hEDS) often make use of complementary and alternative medical (CAM) techniques to manage their chronic pain and other symptoms. Nevertheless, how they use CAM, which techniques they favor, and how CAM use affects their allopathic care remain unclear. The purpose of this qualitative study was to understand patients’ personal experiences with CAM and its ro…
Open article record in new tab ↗ObjectiveThis study analyses the 2020 survey and reviews the 2009, 2014 surveys to ascertain which Behçet's symptoms, personal and family status, patients' lifestyle, and work-related outcomes impacted on Health-Related Quality of Life (HRQoL).MethodsFour hundred and fifty-nine Behçet's patients submitted an online survey/questionnaire. Patients provided information on socio-demographic characteristics, disease du…
Background Almost 90% of patients with dementia suffer from some type of neurobehavioral symptom, and there are no approved medications to address these symptoms. Objective To evaluate the safety and efficacy of the medical cannabis oil "Avidekel" for the reduction of behavioral disturbances among patients with dementia. Materials and methods In this randomized, double-blind, single-cite, placebo-controlled trial…
Background Despite the absence of rigorous prospective studies, there has been an increase in the use of cannabis-based medicinal products. During the study period, the use of medical cannabis in Israel was tightly regulated by national policy. Through a prospective study of approximately 10,000 patients, we aimed to characterize the medical cannabis patient population as well as to identify treatment adherence, s…
Open article record in new tab ↗Aim Intraductal ultrasonography (IDUS) is a highly sensitive and non-invasive detective method that can be used to detect complete calculus clearance during endoscopic retrograde cholangiopancreatography (ERCP). In this study, we examined the preferable timing of IDUS during ERCP lithotomy. Methods From 2017 to 2020, patients with choledocholithiasis were randomized into IDUS-BL (IDUS performed before lithotomy) g…
Open article record in new tab ↗Legalized use of cannabis products and the rising interest in their therapeutic benefits have opened up new opportunities for therapy and marketing. However, the marked variability in formulations, administration modes, therapeutic regimens, and inter- and intra-subject responses make the standardization of medical cannabis-based regimens difficult. Legalization has made the cannabis market highly competitive and…
Open article record in new tab ↗Colorectal cancer is a major public health problem. Unfortunately, currently, no effective curative option exists for this type of malignancy. The most promising cancer treatment nowadays is immunotherapy which is also called biological or targeted therapy. This type of therapy boosts the patient's immune system ability to fight the malignant tumor. However, cancer cells may become resistant to immunotherapy and e…
Open article record in new tab ↗Aim: The aim of this study was to investigate whether the cannabis extract obtained from cannabis flowers that contain the maximum allowed level of mycotoxins affects human safety and health. For that purpose, a novel liquid chromatography with tandem mass spectrometry (LC/MS/MS) method was developed and validated for the determination of aflatoxins and ochratoxin A (OchA) in cannabis extracts to demonstrate that…