Readable research linked to original sources
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Browse normalized, publication-ready research with direct links to its evidence and source.
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Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
Loading articles data…
Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
53 articles
Newest firstDelta-8 THC is a psychoactive cannabinoid typically synthesized from hemp, with similar intoxicating effects as delta-9 THC. Surging public interest alongside the lack of federal regulation of delta-8 THC has led to an unclear legal landscape and increasing safety concerns. Educating young adults about the dangers of delta-8 THC is imperative. The current study investigated the effects of a brief educational video…
Open article record in new tab ↗Alcohol use disorder (AUD) remains a pervasive public health issue with limited effective treatments. Cannabidiol (CBD), a non-psychotropic constituent of cannabis, shows promise in modulating addictive behaviors. This study investigated the effects of chronic CBD administration on alcohol dependence, withdrawal symptoms, and neurodegeneration using two complementary rodent models: chronic intermittent ethanol (CI…
Substance use has been associated with blunted brain responses to non-drug rewards, but findings in people who use cannabis are mixed. Adolescents may be uniquely vulnerable to cannabis-related disruption to reward processing due to ongoing neuromaturation, but longitudinal research is lacking. In this longitudinal fMRI study, we compared brain measures of reward anticipation in 46 adolescents (16–17 years) and ad…
Open article record in new tab ↗Despite substantial progress in preclinical cannabinoid research, translational studies on cannabis use disorders (CUD) are still insufficient due to the absence of robust, validated animal models that fully recapitulate the multifactorial clinical phenotype of human CUD. The complex nature of CUD and the incomplete understanding of its underlying neurobiological mechanisms contribute to the limited availability o…
BACKGROUND: Cannabis is one of the most common substances used during pregnancy. This study examined motivation to quit cannabis use among pregnant women enrolled in a randomized controlled trial of a technology-delivered brief motivational intervention targeting sexually transmitted infection (STI) risk behaviors, including substance use. METHODS: Secondary analyses used data from a clinical trial among pregnant…
Open article record in new tab ↗Prospective memory (PM) deficits are common among people with HIV (PWH) and are linked to poor clinical outcomes. Risk factors for PM deficits in PWH are poorly understood. While cannabis use is associated with worse PM in people without HIV, it is unclear whether this association generalizes to PWH. Three hundred and seven PWH (79% with regular cannabis use) completed the Memory for Intentions Test (MIST). Associ…
Open article record in new tab ↗Background With the rising prevalence of daily cannabis use in the U.S., more individuals may seek treatment for adverse outcomes (e.g., cannabis use disorder) arising from frequent cannabis use. Adaptive interventions leverage self-reported motives for cannabis use to develop personalized support. Research has demonstrated that these motives can be collected on a yearly, monthly, or daily basis, and strongly pred…
Open article record in new tab ↗Cannabis is commonly smoked and often co-used with tobacco, yet evidence on interventions to reduce smoking harms for people who use cannabis is limited. We systematically reviewed evidence on the efficacy and effectiveness of health education interventions (aiming to increase health literacy, knowledge, or motivation) in reducing cannabis smoking and tobacco smoking among people using cannabis. We searched five d…
Background The objective of this qualitative study was to better understand the experiences of individuals living with opioid use disorder (OUD) and chronic pain using medical cannabis (MC) for 12 months. Methods Perspectives were captured via 10 key informant interviews conducted after 12 months of treatment with MC RESULTS: Key themes identified regarding the reasons for initially pursuing MC included: (1) canna…
Background Existing scales that measure cannabis use motives have failed to incorporate the full range of motives that underpin cannabis consumption, especially with the increased use of medical cannabis. The current research aimed to develop a novel, psychometrically robust scale that comprehensively measures cannabis use motives. Here, we report the development and validation of the Comprehensive Cannabis Motive…
Open article record in new tab ↗Background Digital interventions are promising for the prevention of substance use in young people. However, engagement with these interventions is often insufficient, and their full potential remains unrealized. Given the established link between engagement in digital interventions and their effectiveness, understanding user factors that influence involvement in eHealth and mobile health (mHealth) interventions i…
Abstract People with endometriosis report consuming cannabis to manage their symptoms. Given the range of differing legalities and access pathways across the world, this study aimed to investigate the drivers and barriers to cannabis use worldwide. An online, anonymous, cross-sectional survey was distributed internationally by endometriosis organisations and was open to anyone consuming cannabis for endometriosis…
Background Cannabis use is widespread and driven by diverse motives, ranging from recreational purposes to coping with psychological distress. Understanding the underlying reasons for cannabis use, their distribution across different subgroups of people who use cannabis, and how they relate to possible behavior change is essential for developing effective prevention and intervention strategies such as smartphone a…
Open article record in new tab ↗In recent decades, European countries have seen a substantial increase in home cultivation of cannabis. In France, the prevalence of cannabis use continues to increase despite its possession, sale, and cultivation being strictly illegal. The present study aimed to describe the profile and motivations of people in France who cultivate cannabis at home. We separately analyzed data from two convenience samples of peo…
Background: Alcohol and substance use among young people is a well-documented public health concern, and is particularly prevalent in college populations. Problematic internet use is also an emerging issue, with potential negative effects on academic achievement. University dropout remains a critical challenge, especially among freshmen, with research highlighting the role of academic engagement factors such as mo…
Rationale The cannabinoid type-1 receptor (CB1R) signaling pathway plays a central role in regulating motivational and feeding behaviors. Neutral CB1R antagonists represent a promising therapeutic class with potentially fewer adverse effects than inverse agonists, yet their behavioral effects remain incompletely characterized. Objectives We investigated the behavioral profile of AM6527, orally bioavailable neutral…
Open article record in new tab ↗1ObjectiveThis scoping review systematically identifies the extent and nature of evidence regarding willingness, motivators, and barriers influencing community participation in time bank systems, with a focus on older adults. IntroductionTime bank is recognized as an effective tool for enhancing social cohesion and reducing isolation, particularly among older adults. However, specific factors such as barriers and…
Open article record in new tab ↗The shortage of medical professionals in rural and remote areas is a global issue that significantly challenges equitable healthcare delivery. Worldwide, various studies have examined the motivations of medical professionals in choosing their practice location. However, for Mali, this topic remains underexplored, motivating us to conduct this study to identify factors influencing doctors workplace decisions in Mal…
Open article record in new tab ↗The endocannabinoid system comprises highly versatile signaling functions within the nervous system. It is reported to modulate the release of several neurotransmitters, consequently affecting the activity of neuronal circuits. Investigations have highlighted its roles in numerous processes, including appetite-stimulating characteristics, particularly for palatable food. Moreover, endocannabinoids are shown to fin…
Open article record in new tab ↗Cannabis is a gateway drug that can lead to the engagement of other substances. Psychological dysfunctioning and dependence have been highlighted as primary components to substance misuse. The purpose of this study was to investigate what aspects of cannabis use and psychological dysfunctioning are associated with the engagement of other substances and impaired driving. Subject to screening, 200 active adult canna…
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