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Browse normalized, publication-ready research with direct links to its evidence and source.
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Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
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Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
31 articles
Newest firstBackground Super-elderly patients with choledocholithiasis are considered to be at high risk for undergoing surgery. While laparoscopic transcystic common bile duct exploration (LTCBDE) is regarded as a challenging procedure for super-elderly patients with choledocholithiasis, there have been no reported cases of its use in super-elderly patients over the age of 96. Case summary This case study presents the case o…
Open article record in new tab ↗To examine the effects of cannabis on mind-wandering, regular cannabis smokers of legally purchased pre-rolls took part in a three-session remote study. In each 30-min session participants completed three blocks of an attention task in which they pressed the spacebar in time with a metronome tone (the Metronome Response Task), and intermittently reported their levels of spontaneous and deliberate mind-wandering. P…
Open article record in new tab ↗Background Cannabinoid administration has demonstrated promising anti-tumor effects for glioblastoma (GBM) by inhibiting glioma cell proliferation and inducing glioma cell death. However, the impact of cannabinoids and endocannabinoid receptors on immune cells within the tumor microenvironment (TME) remains largely unexplored. Tumor-associated macrophages (TAMs), the most abundant immune cells in the TME, and thei…
Open article record in new tab ↗The objective of this study was to investigate the morphological and chemical properties of hemp bast RPF1 variety fiber to be used as a potential raw material for filter paper production. Experimental handsheet samples with basis weight of 20 g/m2 were manufactured using mixture of hemp and softwood pulp at various beating levels. The average fiber length and width of hemp bast fiber were determined as 5.76 mm an…
Open article record in new tab ↗Over the past 10 years, materials science and engineering have shown increasing interest in incorporating lignocellulosic fibers into polymer and hybrid composites (LCF-CPH). This bibliometric analysis, covering the period 2012 to 2022, examines the current state of research on the application of these fibers in composites, with the aim of identifying significant contributions, new trends, and possible future dire…
Open article record in new tab ↗The crystallographic, optical, and electrical properties of manganese sulfide thin films depend on the control of the temperature precursors in the synthesis process, as shown by the results of this work. MnS thin films were deposited on glass substrates using the SILAR method and over an additional layer of CdS synthesized by chemical bath deposition (CBD) to acquire a p-n heterojunction. SILAR is an inexpensive…
Open article record in new tab ↗Background Smoking is responsible for 80 % of cases of Chronic Obstructive Pulmonary Disease (COPD), while the prognosis is improved by smoking cessation (SC). We examined clinical factors associated with SC among smokers with COPD comparing women and men. Methods The study comprised a cohort of 1470 smokers who visited a SC service and completed at least 28-day of follow-up visits. The outcome was smoking status…
Accidental chemical spills can result in styrene-contaminated soil. Styrene negatively affects human health and the environment. The objective of this study was to remediate styrene-contaminated soil using a combination of activated carbon-based nanoscale zero-valent iron (nZVI-AC) and phytoremediation by sunn hemp (Crotalaria juncea), zinnia (Zinnia violacea Cav.) and marigolds (Tagetes erecta L.). The results sh…
The growing interest in the therapeutic potential of cannabidiol (CBD) has led to the need for effective and reliable delivery methods that overcome its low oral absorption. Zeolites, a class of porous nanoparticles, offer unique advantages as drug carriers due to their high surface area and adjustable pore size. In this study, a zeolite-based drug delivery system was developed for the encapsulation of CBD. The ze…
Open article record in new tab ↗The combination of Chaidangbo (CDB) is an antidepressant traditional Chinese medicine (TCM) prescription simplified by Xiaoyaosan (a classic antidepressant TCM prescription) through dismantling research, which has the effect of dispersing stagnated liver qi and nourishing blood in TCM theory. Although the antidepressant effect of CBD has been confirmed in animal studies, the material basis and possible molecular m…
HD-Zip (Homeodomain-Leucine Zipper) is a family of transcription factors unique to higher plants and plays a vital role in plant growth and development. Increasing research results show that HD-Zip transcription factors are widely involved in many life processes in plants. However, the HD-Zip transcription factor for cannabis, a valuable crop, has not yet been identified. The sequence characteristics, chromosome l…
Open article record in new tab ↗CBD is the primary noneuphorizing and nonaddictive compound of cannabis. It has recently been shown to possess considerable therapeutic potential for treating a wide range of neuropsychiatric disorders in humans, such as anxiety. In addition to humans, domestic cats are provided with such endocannabinoid system with which CBD interacts almost in the same manner researchers think it does in humans. However, little…
Open article record in new tab ↗Recent human clinical studies indicate that cannabidiol (CBD), the primary non-addictive component of cannabis, possesses considerable therapeutic potentials. The purpose of the present study was to explore the possibility of effects of CBD administration on behaviors of healthy domestic dogs. It is well-known that when temporarily separated from their caregivers, they may show an increase in vocalization. Here th…
Open article record in new tab ↗The interest in characterization of drugs abused started in 1948 with the aim of determining the origin of opium. After 75 years there is still a great interest in this approach, called geo-profiling, chemical or forensic profiling in the following decades. Recently chemical attribution signatures (CAS) were proposed by the authors who studied "synthesis precursors and byproducts, impurities, degradation products,…
Cannabis sativa L.-based food supplement products in pharmacies and para pharmacies in Portugal increased by 84 % between 2021 and 2022, arousing consumers' curiosity. However, information about these products is limited, and consumers are not aware of the restrictions in current European regulations. This study aims to understand Portuguese consumers' perceptions of cannabis products and identify the distribution…
Open article record in new tab ↗Terpene synthases (TPSs) regulate plant growth, development, and stress response. TPS genes have been identified in Arabidopsis thaliana and Zea mays. Cannabis sativa TPS genes were identified and analyzed using bioinformatics. Genomic data were downloaded from Plant Transcription Factor Database and National Center for Biotechnology Information database, and TPS genes were predicted, analyzed, and visualized usin…
Open article record in new tab ↗The aim of this study was to develop and additively manufacture polypropylene-hemp fiber (PPHF) composites, which were composed of polypropylene (PP) and hemp fibers (HF) in various percentages (5%, 10%, and 20%). The objective was to examine the mechanical properties and water absorption behaviors of extruded PP, conventional filament PP and PPHF composites. The findings of the flexural and tensile tests provided…
Open article record in new tab ↗Policosanols (PCs) are bioactive compounds extracted from different natural waxes. In this work, the purification, characterization and assessment of the antioxidant and anti-inflammatory activity was carried out on PCs from an innovative source, i.e. a waxy material from supercritical-fluid extraction (SFE) of non-psychoactive Cannabis sativa L. (hemp) inflorescences. Starting from this material, PCs were obtaine…
Background The recent interest among consumers in industrial hemp due to health and wellness benefits has led to several products from industrial hemp, including cannabidiol (CBD) oil. CBD oil extraction from hemp buds and flowers generates by-product biomass (hemp flakes), often posing disposal challenges and with little or no applications. We hypothesized that hemp flakes possess residual compounds with nutritio…
Open article record in new tab ↗Given the growing interest in non-toxic materials with good anti-inflammatory and antimicrobial mechanical properties, this work focuses on preparing chitosan sponges with violacein and cannabis oil crosslinked with dialdehyde chitosan. The sponge was tested for its physicochemical and biological properties, presenting a high swelling rate, good thermal stability, and satisfactory mechanical properties. The obtain…
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