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Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
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Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
17 articles
Newest firstThree-dimensional (3D) printing has emerged as a versatile platform in pharmaceutical sciences, enabling fabrication of personalized dosage forms with controlled drug release and tailored properties using printable hydrogel bioinks. This study aimed to develop mucoadhesive hydrogel buccal films for cannabinoid delivery using extrusion-based 3D bioprinting. The films incorporated cannabidiol (CBD) and tetrahydrocan…
Open article record in new tab ↗BACKGROUNDCranioplasty is an essential procedure to restore cranial integrity, protect neural structures, and improve cosmetic outcomes. However, commercially available implants are often costly, limiting their accessibility in public healthcare systems. Three-dimensional (3D) printing offers a low-cost alternative for producing patient-specific solutions. METHODSA retrospective case series of eight patients under…
Open article record in new tab ↗3D printing with biodegradable polymers such as polylactic acid (PLA) is a sustainable alternative to conventional petroleum-derived plastics. However, improving the mechanical properties of PLA remains a challenge. This study explores the incorporation of chemically treated hemp fibers to improve the interfacial adhesion and mechanical strength of PLA filaments. Samples with PLA and hemp were prepared by subjecti…
The photopolymerization process in 3D printing is considered greener once it involves a fast reaction and low energy consumption. Various reactions for photopolymerization can be used nowadays, but a special one is the thiol-ene "click" reaction that occurs in equimolar concentrations of thiol and alkene groups. In this sense, solvent-free photopolymerizable formulations were prepared to contain non-modified casto…
Open article record in new tab ↗The technology of 3D printing has become one of the most effective methods of creating various parts, such as those used for fast prototyping. The most important aspect of 3D printing is the selection and application of the appropriate material, also known as filament. The current review concerns mainly the description of the mechanical and physical properties of the different filaments and the possibilities of im…
Open article record in new tab ↗Oropharyngeal dysphagia and pain are prevalent concerns in the geriatric population. Therefore, this study investigates advances in the development of cannabidiol (CBD) gummies using 3D printing technology and compares them to commercially available molded gummies for pain management. A gelatin-based CBD formulation was prepared and printed using a syringe-based extrusion 3D printer. The formulation's rheological…
Open article record in new tab ↗IntroductionPersonalized 3D-printed kidney models could serve as valuable educational tools for patients undergoing robot-assisted partial nephrectomy. These models facilitate patients understanding of their pathology, surgical procedure, and anatomy. However, the costs associated with personalized printing remain a barrier to their use. This study aims to thoroughly investigate the benefits of using a personalize…
Cannabidiol (CBD) has been recognized for its numerous therapeutic benefits, such as neuroprotection, anti-inflammatory effects, and cardioprotection. However, CBD has some limitations, including unpredictable pharmacokinetics and low oral bioavailability. To overcome the challenges associated with CBD delivery, we employed Design of Experiments (DoE), lipid carriers, and 3D printing techniques to optimize and dev…
The aim of this study was to develop and additively manufacture polypropylene-hemp fiber (PPHF) composites, which were composed of polypropylene (PP) and hemp fibers (HF) in various percentages (5%, 10%, and 20%). The objective was to examine the mechanical properties and water absorption behaviors of extruded PP, conventional filament PP and PPHF composites. The findings of the flexural and tensile tests provided…
Open article record in new tab ↗Rationale Inhalation of airborne stimuli can damage the airway epithelium, increasing the risk of developing respiratory or systemic diseases. In vitro studies using air-liquid interface cell cultures enable controlled investigation of cellular responses to relevant exposures. Commercial in vitro exposure systems provide precise and reproducible dosage but require significant capital investment and are not amenabl…
Cholangiopathy is a diverse spectrum of chronic progressive bile duct disorders with limited treatment options and dismal outcomes. Scaffold- and stem cell-based tissue engineering technologies hold great promise for reconstructive surgery and tissue repair. Here, we report a combined application of 3D scaffold fabrication and reprogramming of patient-specific human hepatocytes to produce implantable artificial ti…
In this study, digital light processing (DLP) was used to achieve 3D-printed composite materials containing photosensitive resin blended with starch and hemp fibers. The synthesis of 3D-printed composites was performed without heating, according to various material combinations ranging from pure photosensitive resin to a mixture of three phases, including resin, starch, and hemp fibers, with the weight content for…
Background Plant growth devices, for example, rhizoponics, rhizoboxes, and ecosystem fabrication (EcoFAB), have been developed to facilitate studies of plant root morphology and plant-microbe interactions in controlled laboratory settings. However, several of these designs are suitable only for studying small model plants such as Arabidopsis thaliana and Brachypodium distachyon and therefore require modification t…
Open article record in new tab ↗Native collagen doughs were processed using a syringe-based extrusion 3D printer to obtain collagen scaffolds. Before processing, the rheological properties of the doughs were analyzed to determine the optimal 3D printing conditions. Samples showed a high shear-thinning behavior, reported beneficial in the 3D printing process. In addition, tetrahydrocurcumin (THC) was incorporated into the dough formulation and it…
Open article record in new tab ↗Hemp fiber was used untreated and treated with sodium hydroxide or (3-aminopropyl)triethoxysilane (APTES) as an additive in polylactic acid (PLA) for fused filament fabrication (FFF) of tensile test specimens. Composites granules were produced by solvent processing with 10 wt. % of hemp fiber to use as feedstock for the extrusion of filaments compatible with commercial FFF printers. The dataset shows the thermal p…
Open article record in new tab ↗Due to supply chain disruption, the COVID-19 pandemic has caused severe shortages in personal protective equipment (PPE) for health care professionals. Local fabrication based on 3D printing is one way to address this challenge, particularly in the case of simple products such as protective face shields. As a consequence, many public domain designs for face shields have become available. No clear path exists, howe…