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Review Article 2026CC BYFree full text

Exercise-induced anandamide–CB1R signaling and prefrontal–amygdala stress circuits in adolescent depression: a critical hypothesis-driven narrative review

Yongxin Luan, Shupei Wang, Yutang Gao, Qiang Kong, Zhenhua Ma, Chuankai Luan

Adolescent depression emerges during a developmental period characterized by ongoing maturation of corticolimbic and stress-regulatory systems. This narrative review critically evaluates a hypothesis that acute exercise-related endocannabinoid mobilization, particularly changes in circulating anandamide (AEA), may be linked to CB1 receptor (CB1R)-dependent processes relevant to prefrontal–amygdala function and str…

Frontiers in Psychiatry PubMed Central Open Access

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Research Article 2026CC BYFree full text

Substance Use Behaviors as Markers of Emotional Dysregulation and Childhood Adversity Among Adult Emergency Department Patients.

Amar Kassim, Abdulla Sabry, Christina Schweitzer, Rosemarie Burynski, Alexandra DiGiovanni, Doi Bu +4 more

Introduction Substance use is frequently encountered in emergency department (ED) visits and may reflect underlying emotional or developmental challenges. Adverse childhood experiences (ACEs) are linked to both emotional dysregulation and later substance use, but this relationship is rarely examined in acute care settings. We investigated whether recent substance use, as measured by the Tobacco, Alcohol, Prescript…

Cureus

Research Article 2024CC BY-NCFree full text · non-commercial reuse

Emotional dysregulation in relation to substance use and behavioral addictions: Findings from five separate meta-analyses.

Alba González-Roz, Yasmina Castaño, Andrea Krotter, Angie Salazar-Cedillo, Elena Gervilla

Background/objective Emotional dysregulation (ED) is a transdiagnostic variable underlying various psychiatric disorders, including addictive behaviors (ABs). This meta-analysis examines the relationship between ED and ABs (alcohol, tobacco, cannabis, gambling, and gaming), and indicators of AB engagement (frequency, quantity/time of use, severity, and problems). Method Searches were conducted in PubMed, Scopus, W…

International Journal of Clinical and Health Psychology : IJCHP Europe PMC

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Research Article 2020CC BY-NCFree full text · non-commercial reuse

Alcohol and drug use disorders in adult attention-deficit/hyperactivity disorder: Prevalence and associations with attention-deficit/hyperactivity disorder symptom severity and emotional dysregulation.

Espen Anker, Jan Haavik, Trond Heir

BACKGROUND: High risk of alcohol and drug use disorders in people with attention-deficit/hyperactivity disorder (ADHD) calls for exploratory research of relationships with clinical features of ADHD. AIM: To estimate prevalence of alcohol/drug use disorders and associations with ADHD symptom severity and emotional dysregulation, in adults with ADHD. METHODS: This observational cross-sectional clinical study consist…

World Journal of Psychiatry PubMed Central Open Access

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Articles

Articles

Exercise-induced anandamide–CB1R signaling and prefrontal–amygdala stress circuits in adolescent depression: a critical hypothesis-driven narrative review

Substance Use Behaviors as Markers of Emotional Dysregulation and Childhood Adversity Among Adult Emergency Department Patients.

Emotional dysregulation in relation to substance use and behavioral addictions: Findings from five separate meta-analyses.

Alcohol and drug use disorders in adult attention-deficit/hyperactivity disorder: Prevalence and associations with attention-deficit/hyperactivity disorder symptom severity and emotional dysregulation.