Readable research linked to original sources
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Browse normalized, publication-ready research with direct links to its evidence and source.
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Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
Loading articles data…
Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
7 articles
Newest firstBackgroundLow participant recruitment and retention rates are a significant barrier to successful Randomised Controlled Trials (RCTs). A Study Within A Trial (SWAT) is an effective way to explore which trial delivery methods may be useful for improving participant recruitment and retention rates. Infographics are a useful information delivery tool that may improve participants understanding of the trial and thus i…
Open article record in new tab ↗Purpose To summarise the extent and type of evidence in relation to adverse events (AEs) associated with the use of cannabis-based products (CBP) in people living with cancer. Methods The Joanna Briggs Institute (JBI) methodology for scoping reviews was applied. A search was performed in MEDLINE (Ovid), Embase (Ovid), CINAHL (EBSCOhost), Scopus, Web of Science Core Collections and AMED (Ovid) from their inception…
Open article record in new tab ↗Background Although clozapine is the most effective antipsychotic for people with treatment-resistant schizophrenia (TRS), only 40% of people with TRS respond, and there is limited evidence for augmentation agents. Cannabidiol (CBD) reduces positive symptoms in individuals with schizophrenia, but no trials have specifically examined its efficacy in those with clozapine-resistant schizophrenia. Aims To examine the…
BackgroundNHS England issued commissioning guidance on 18 low-priority treatments which should not be routinely prescribed in primary care. We aimed to monitor the impact of an educational intervention delivered to regional prescribing advisors by senior pharmacists from NHS England on the primary care spend on low-priority items. MethodsAn opportunistic randomised, controlled parallel-group trial. Participants (c…
Open article record in new tab ↗BackgroundImproving the efficiency of clinical trials is key to their continued importance in directing evidence-based patient care. Digital innovations, in particular the use of electronic healthcare records (EHR), allow for large-scale screening and follow-up of participants. However, it is critical these developments are accompanied by robust and transparent methods that can support high quality and high clinic…
ObjectiveTo assess accelerated partner therapy (APT) as a contact tracing intervention for people with chlamydia. DesignCross-over cluster-randomised controlled trial. Setting17 sexual health clinics (clusters) in the United Kingdom, 2018-2019. ParticipantsHeterosexual people aged over 16 years with a positive Chlamydia trachomatis test result and/or clinical diagnosis of pelvic inflammatory disease, cervicitis, n…
BackgroundExercise can improve physical function and slow the progression of dementia. However, uncertainty exists around the cost-effectiveness of exercise programmes for people with early dementia. ObjectiveThe aim is to determine whether a home-based supervised exercise programme (PrAISED - promoting activity, independence, and stability in early dementia) can generate a positive social return on investment (SR…