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Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
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Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
2 articles
Newest firstBackground Synaptic loss is characteristic of many neurodegenerative diseases; it occurs early and is strongly related to functional deficits. Objective In this longitudinal observational study, we determine the rate at which synaptic density is reduced in the primary tauopathies of progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD), and we test the relationship with disease progression. Meth…
Open article record in new tab ↗BackgroundSynaptic loss is a prominent and early feature of many neurodegenerative diseases. ObjectivesWe tested the hypothesis that synaptic density is reduced in the primary tauopathies of progressive supranuclear palsy (PSP-Richardsons syndrome) and amyloid-negative corticobasal syndrome (CBS). MethodsForty four participants (15 CBS, 14 PSP, and 15 age-/sex-/education-matched controls) underwent positron emissi…
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