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Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
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Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
15 articles
Newest firstThis study aimed to investigate the antithrombotic activity of hemp seed peptides derived from trypsin hydrolysates and elucidate their molecular mechanisms using a ponatinib-induced zebrafish (Danio rerio) thrombosis model. Through ultrafiltration and LC-MS/MS analysis, we identified 1741 peptide sequences (< 3 kDa), with 67% distributed in the 0.5-1.5 kDa range. In vivo experiments demonstrated that 125 μg/mL he…
Open article record in new tab ↗Delivery of nutritious foods with a reduced carbon footprint is essential to deliver a circular food system. This paper represents a thorough analysis of protein solubility, lipid stability, and physical properties of four hemp by-products and seven hemp seed foods to help evaluate their potential to replace less sustainable food ingredients like soya, wheat flour, and palm fat. The hemp seed-hull flour and expell…
Open article record in new tab ↗This research investigates how oven and microwave drying methods influence mass reduction, oil yield, chemical composition, and bioactivity of Cannabis sativa seed oil, from two C. sativa L. varieties-Beldia and Critical-grown in Ketama and Taounate, Morocco. Microwave drying resulted in greater mass loss (2.1%-1.8%) compared to oven drying (1.48%-1.1%), but reached moisture stabilization within just 25 min, signi…
One significant reductive metabolite of curcumin, tetrahydroxycurcumin (THC), is a promising oncology candidate because of its multifunctional bioactivities. Preclinical data indicate that THC has a strong anti-inflammatory, antioxidant, and anticancer profile, and as such, it is a better alternative to curcumin in treatment. Mechanistically, THC regulates important transcriptional factors that are involved in tum…
While gut-to-systemic translocation of pyrogenic endotoxin due to a leaky gut elicits systemic inflammation, at the intestine, the endocannabinoid system (eCB) also plays a major role in modulating the impact of gut dysbiosis on the host system. Therefore, we hypothesized that coadministration of prebiotic inulin with probiotics would improve the eCB system, gut microbial composition, and inflammatory parameters a…
Open article record in new tab ↗AbstractPeripheral nerve injuries are one of those complex medical conditions for which a highly effective first‐line treatment is currently missing. The use of natural compound as medicines to treat various disorders has a long history. Our previous research explored that crude Cannabis sativa L. accelerated the recovery of sensorimotor functions following nerve injury. The purpose of the current study was to inv…
AbstractIn this work, the protein quality of defatted hemp hearts and protein‐enriched hemp fractions was determined. Protein quality was assessed using a rodent bioassay to evaluate growth and protein digestibility, while amino acid composition was determined via HPLC. A method for determining in vitro protein digestibility was compared to in vivo methodology and used to generate an in vitro protein quality score…
Open article record in new tab ↗Severe shrimp disease outbreaks have a destructive impact on shrimp aquaculture and its associated downstream food processing industries. Thus, it is essential to develop proper methods for shrimp disease control, which emphasizes the importance of food safety. In this study, we performed biochemical tests and gut microbiome analysis using uninfected control and Vp AHPND-infected Penaeus monodon samples. Biochemic…
Open article record in new tab ↗The aim of this study was to analyze the fatty acid (FA) profiles and mycotoxin and polycyclic aromatic hydrocarbon (PAH) concentrations in sea buckthorn (SB1, SB2), flaxseed (FL3, FL4, FL5), hempseed (HE6, HE7, HE8), camelina (CA9, CA10), and mustard (MU11) edible oils, prepared by artisans' by artisanal at small-scale agricultural companies in Lithuania. The dominant FAs were palmitic and oleic acids in SB; palm…
Open article record in new tab ↗Foodborne protein hydrolysates exhibit biological activity that may be therapeutic in a number of human disease settings. Hemp peptides (HP) generated by controlled hydrolysis of hemp proteins have a number of health benefits and are of pharmaceutical value. In the present study, we produce small molecular weight HP from hemp seed and investigate its anticancer properties in Hep3B human liver cancer cells. We demo…
Open article record in new tab ↗Recently, due to the valuable and high level of phytochemical compounds such as cannabinoids and other secondary metabolites, the cultivation of Cannabis sativa has increased in the world. The current study was conducted to evaluate the potential role of exogenous salicylic acid (control, 0.01, 0.1, and 1 M) on enhanced production of pharmaceutically important phytochemicals. The sprayed aerial parts were evaluate…
Open article record in new tab ↗Indispensable amino acid (IAA) composition and standardized ileal digestibility (SID) of five animal- and 12 plant-based proteins were used to calculate their respective Digestible Indispensable Amino Score (DIAAS) according to the three age categories defined by the Food and Agriculture Organization (FAO). Mean IAA content and mean SID obtained from each protein dataset were subsequently used to simulate optimal…
Open article record in new tab ↗In this study, the effect of solvent ratio of hexane to isopropanol (0:100, 50:50, and 100:0 v/v%), extraction temperature (30, 45, and 60°C), and time (30, 60, and 90 min) were investigated on the oil extraction efficiency, total phenol content, DPPH radical scavenging, peroxide value, and oil color index. Extraction conditions were optimized by response surface methodology and Box-Behnken design. The optimal con…
Open article record in new tab ↗Adsorption and desorption isotherms of hemp seeds with 0%, 5%, 10%, 15%, and 20% of dockage were determined using the salt solution static (SSS) method. The wet hemp seeds with 0% dockage were also dried at 30℃ with 50% RH, 35℃ with 30% and 50% RH, and 40℃ with 30% and 50% RH inside a thin-layer dryer (thin-layer dynamic method). The hemp seeds with different percentages of dockage showed hysteresis, and this hyst…
Open article record in new tab ↗The demand for products of high nutritional value from sustainable sources is growing rapidly in the global food market. In this study, the effect of pH on the functional properties of lupin, green pea, fava bean, hemp, and buckwheat flours was investigated and compared with wheat flour. Functional properties included solubility, emulsifying and foaming properties, gelling ability, and water holding capacity (WHC)…
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