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Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
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Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
3 articles
Newest firstPrenatal cannabis exposure (PCE) is increasingly prevalent and has been associated with adverse neurodevelopmental outcomes, yet its molecular impact on brain reward circuitry remains poorly defined. Here, we investigated transcriptional and epigenomic alterations in the nucleus accumbens (NAc) following prenatal Δ 9 -tetrahydrocannabinol exposure in a rat model using snRNA-seq and snATAC-seq analyses. PCE markedl…
Open article record in new tab ↗This study aimed to investigate the antithrombotic activity of hemp seed peptides derived from trypsin hydrolysates and elucidate their molecular mechanisms using a ponatinib-induced zebrafish (Danio rerio) thrombosis model. Through ultrafiltration and LC-MS/MS analysis, we identified 1741 peptide sequences (< 3 kDa), with 67% distributed in the 0.5-1.5 kDa range. In vivo experiments demonstrated that 125 μg/mL he…
Open article record in new tab ↗Foodborne protein hydrolysates exhibit biological activity that may be therapeutic in a number of human disease settings. Hemp peptides (HP) generated by controlled hydrolysis of hemp proteins have a number of health benefits and are of pharmaceutical value. In the present study, we produce small molecular weight HP from hemp seed and investigate its anticancer properties in Hep3B human liver cancer cells. We demo…
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