Readable research linked to original sources
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Browse normalized, publication-ready research with direct links to its evidence and source.
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Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
Loading articles data…
Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
10 articles
Newest firstThe British Association for Psychopharmacology guidelines for the management of substance dependence focus primarily on the pharmacological aspects of treatment. A group of international experts from a wide range of disciplines reviewed the current evidence in their field, considered the strength of the evidence and discussed the clinical implications at a consensus meeting. The guidelines focus on the pharmacolog…
Open article record in new tab ↗Artificial intelligence (AI) is gradually transforming healthcare. However, despite its promised benefits, AI in healthcare also raises a number of ethical, legal and social concerns. Compliance by design (CbD) has been proposed as one way of addressing some of these concerns. In the context of healthcare, CbD efforts could focus on building compliance with existing clinical guidelines (CGs), given that they provi…
Open article record in new tab ↗BackgroundLarge language models (LLMs) are increasingly used in healthcare, but standardized benchmarks fail to capture their validity and safety in real-world scenarios. Evaluating their quality and reliability is critical for safe integration into practice. MethodsFour fictitious clinical vignettes (orthopedics, pediatrics, gynecology, psychiatry) were developed by independent specialists and tested in four conv…
IntroductionEconomic evaluations in healthcare can guide practice and inform policy. The objective of this paper is to present the protocol for a health economic evaluation comparing the cost-effectiveness of prophylactic treatment using pantoprazole 40 mg IV daily compared to no pantoprazole to prevent upper gastrointestinal (GI) bleed among invasively ventilated patients. Methods and analysisThis is an economic…
Introduction Pennsylvania opened its first medical marijuana (MMJ) dispensary in 2018. Qualifying conditions include six conditions determined to have no or insufficient evidence to support or refute MMJ effectiveness. We conducted a study to describe MMJ dispensary access in Pennsylvania and to determine whether dispensary proximity was associated with MMJ certifications and community demographics. Methods Using…
Open article record in new tab ↗Purpose of review This document critically examines the role of cannabinoids in cancer care during an era marked by rapid advancements in oncology and changing perceptions on cannabis. It traces the historical context of cannabis in medicinal use, navigating its journey from widespread acceptance, subsequent criminalization, to its resurgence in modern therapeutic applications, particularly within the framework of…
Open article record in new tab ↗ObjectivesMedical research in Syria faced significant limitations due to inadequate human and financial resources, exacerbated by the ongoing war. Until recently, the curriculum did not incorporate sufficient training on research skills. Consequently, extracurricular workshops were initiated or utilized nationwide to acquire research-related expertise, aiming to bolster research output. This study aims to characte…
Open article record in new tab ↗Cannabinoid drugs are registered for postoperative nausea and emesis, Tourette syndrome and tumor-related anorexia, but are also used for spasticity and pain relief, among other conditions. Clinical studies for spasmolysis have been equivocal and even conclusions from meta-analyses were not consistent. This may be due to uncertainty in diagnostic criteria as well as a lack of direct spasmolytic activity (direct ca…
Open article record in new tab ↗BackgroundClinical practice guidelines (CPGs) aim to standardize clinical care. Increasingly, hospitals rely on locally produced guidelines alongside national guidance. This study examines variation between national and local CPGs, using the example of acute paediatric asthma guidance from the United Kingdom and the Netherlands. MethodsFifteen British and Dutch local CPGs were collected with the matching national…
Background and aims This review appraises the progression and status of the evidence base for the treatment of compulsive buying disorder (CBD), in order to highlight what currently works and to prompt useful future research. Methods Online databases ISI Web of Knowledge, PsycINFO, and PubMed via Ovid were searched at two time points. Two quality checklists and an established model of therapy evaluation (hourglass…
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