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Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
Loading articles data…
Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
3 articles
Newest firstHigh fructose diet is a major risk factor for metabolic syndrome (MetS). The gut bacterium Akkermansia muciniphila (A. muciniphila) has been shown to improve fructose-induced MetS, but the underlying mechanism remains unclear. Here, we investigated how A. muciniphila modulates fructose-induced MetS using multitissue, multiomics studies encompassing gut microbiota, plasma and gut metabolome, and hypothalamus single…
Open article record in new tab ↗Background Cannabis use is on the rise yet the systematic molecular impact of key cannabinoid components on various tissues in diverse organisms remains incompletely understood. We aim to systematically elucidate the molecular pathways and networks affected by delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) across species and tissue types. Methods We curated 105 THC- and CBD-related RNA sequencing (RNAseq…
Open article record in new tab ↗During adolescence, frequent and heavy cannabis use can lead to serious adverse health effects and cannabis use disorder (CUD). Rodent models of adolescent exposure to the main psychoactive component of cannabis, delta-9-tetrahydrocannabinol (THC), mimic the behavioral alterations observed in adolescent users. However, the underlying molecular mechanisms remain largely unknown. Here, we treated female and male C57…
Open article record in new tab ↗