Readable research linked to original sources
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Browse normalized, publication-ready research with direct links to its evidence and source.
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Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
Loading articles data…
Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
5 articles
Newest firstBackground The diathesis-stress paradigm and the cannabinoid-hypothesis have been proposed as possible pathophysiological models of schizophrenia. However, they have historically been studied independently of each other. Objective This PRISMA 2020-compliant systematic review aimed at reappraising the interplay between the hypothalamic-pituitary-adrenal (HPA) axis and the endocannabinoid (eCB) system in psychosis-…
Open article record in new tab ↗BackgroundHypertension and diabetes share common pathophysiological mechanisms and hence have a high likelihood of co-occurring. The co-existence of hypertension and diabetes increases cardiovascular disease risk and healthcare spending. This review aimed to estimate the burden of hypertension among people with diabetes in African countries. MethodsThis review was registered in the International Prospective Regist…
Open article record in new tab ↗Cannabis use disorder (CUD) co-occurs with major depressive disorder (MDD) more frequently than would be expected by chance. However, studies to date have not produced a clear understanding of the mechanisms underlying this co-morbidity. Genetically informative studies can add valuable insight to this problem, as they allow the evaluation of competing models of co-morbidity. This study uses data from the Australia…
Open article record in new tab ↗Highlights•We studied the extent that cigarette smoking predicts level of cannabis addiction.•We tested whether cigarette smoking mediates the effect of cannabis use on dependence.•We interviewed 298 cannabis and tobacco users, of which 65 were followed up.•Cigarette smoking accounted for 29% of the variance in cannabis dependence.•Cigarette smoking mediated the relationship between cannabis use and dependence. Ai…
Objective:The aim of this paper was to systematically review and meta-analyse the prevalence of co-morbid psychiatric disorders (DSM-IV Axis I disorders) among treatment-seeking problem gamblers.Methods:A systematic search was conducted for peer-reviewed studies that provided prevalence estimates of Axis I psychiatric disorders in individuals seeking psychological or pharmacological treatment for problem gambling…