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Browse normalized, publication-ready research with direct links to its evidence and source.
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Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
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Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
14 articles
Newest firstBackgroundSickle cell disease (SCD) is concentrated in sub-Saharan Africa, where delivery of guideline-referenced care remains challenging. Current evaluation approaches rely largely on access indicators and clinical outcomes, which do not directly measure care delivery. We developed the Care Delivery Gap (CDG) framework, a patient-reported approach for identifying care-process omissions, and conducted a proof-of-…
Open article record in new tab ↗Severe neonatal hyperbilirubinemia remains a leading cause of preventable neonatal morbidity and mortality in low- and middle-income countries (LMICs), where unreliable electricity supply, limited specialist availability, and high treatment costs constrain access to effective phototherapy. There is limited evidence on scalable, climate-resilient phototherapy solutions suitable for decentralised care delivery. We c…
IntroductionChronic lung disease (CLD) represents a substantial health burden in low- and middle-income countries (LMICs). However, in-depth CLD studies in Kyrgyzstan, where CLD is highly prevalent, remain scarce. ObjectivesTo explore in Kyrgyzstan (1) beliefs, perceptions and behaviors regarding CLD among community members (CMs), (2) relations between illness perceptions, demographics, behaviors and setting (high…
IntroductionFemale Sex Workers in Low- and Middle-Income Countries face increased risks of violence, exploitation, stigma, and limited access to healthcare, leading to vulnerability in their communities. Modern communication technologies have transformed FSW interactions with clients, facilitating easier and more accessible connections. This scoping review explores the use of social media by women involved in sex…
Open article record in new tab ↗BackgroundAntenatal anaemia is a significant global health problem, affecting 48% of pregnant women in South Asia. The standard of care in Bangladesh is oral iron and folic acid supplementation. However, access and adherence to oral iron supplementation are subpar. An alternative treatment available to address antenatal anaemia is intravenous (IV) iron. Modern IV iron products are routinely used in high-income cli…
BackgroundPostpartum modern contraception is crucial for preventing unintended pregnancies, reducing short inter-pregnancy intervals, and improving maternal and child health outcomes. Family planning counseling, when engaging with maternal healthcare services, may enhance modern contraceptive uptake in the postpartum period. However, evidence in low- and middle-income countries (LMICs) has yielded conflicting find…
The global population is undergoing a significant surge in aging leading to increased susceptibility to various forms of progressive illnesses. This phenomenon significantly impacts both individual health and healthcare systems. Low and Middle Income Countries face particular challenges, as their Primary Health Care (PHC) settings often lack the necessary human and material resources to effectively address the esc…
Open article record in new tab ↗It is quite well-documented that the COVID-19 pandemic disrupted cancer screening services in all countries, irrespective of their resources and healthcare settings. While quantitative estimates on reduction in volume of screening tests or diagnostic evaluation are readily available from the high-income countries, very little data is available from the low- and middle-income countries (LMICs). From the CanScreen5…
BackgroundIn March 2020 the South African COVID-19 Modelling Consortium was formed to support government planning for COVID-19 cases and related healthcare. Models were developed jointly by local disease modelling groups to estimate cases, resource needs and deaths due to COVID-19. MethodsThe National COVID-19 Epi Model (NCEM) while initially developed as a deterministic compartmental model of SARS-Cov-2 transmiss…
SARS-CoV-2 seroprevalence surveys provide critical information to assess the burden of COVID-19, describe population immunity, and guide public health strategies. Early in the pandemic, most of these surveys were conducted within high-income countries, leaving significant knowledge gaps in low-and middle-income (LMI) countries. To address this gap, the U.S. Centers for Disease Control and Prevention (CDC) is suppo…
Open article record in new tab ↗BACKGROUND: Screening, brief intervention and referral to treatment (SBIRT) programmes have resulted in generally positive outcomes in healthcare settings, particularly for problem alcohol use, yet implementation is hampered by barriers such as concerns regarding the burden on healthcare professionals. In low-resourced settings, task-sharing approaches can reduce this burden by using non-professional healthcare wo…
Introduction Multimorbidity describes the presence of two or more long-term conditions, which can include communicable and non-communicable diseases, and mental disorders. The rising global burden from multimorbidity is well-documented, but trial evidence for effective interventions in low- and middle-income countries (LMICs) is limited. Selection of appropriate outcomes is fundamental to trial design to ensure cr…
Open article record in new tab ↗BackgroundCoronavirus disease 2019 (COVID-19) epidemics strain health systems and households. Health systems in Africa and South Asia may be particularly at risk due to potential high prevalence of risk factors for severe disease, large household sizes and limited healthcare capacity. MethodsWe investigated the impact of an unmitigated COVID-19 epidemic on health system resources and costs, and household costs, in…
Open article record in new tab ↗BACKGROUND: Understanding relationships between substance use and suicidal ideation and behaviour (SIB) has important public health implications for suicide prevention in low- and middle-income countries (LMICs), where 75% of suicides occur. This systematic review explored the associations between substance use and SIB in LMICs. METHODS: We searched five databases using a combination of keywords for substance use,…
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