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Research Article 2024CC BYFree full text

Endocannabinoids, endocannabinoid-like compounds and cortisone in head hair of health care workers as markers of stress and resilience during the early COVID-19 pandemic.

Ingeborg Biener, Tonina T. Mueller, Jin Lin, Han Bao, Julius Steffen, Marion Hoerl +12 more

The pandemic caused by SARS-CoV-2 impacted health systems globally, creating increased workload and mental stress upon health care workers (HCW). During the first pandemic wave (March to May 2020) in southern Germany, we investigated the impact of stress and the resilience to stress in HCW by measuring changes in hair concentrations of endocannabinoids, endocannabinoid-like compounds and cortisone. HCW (n = 178) r…

Translational Psychiatry Europe PMC

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Research Article 2021CC BYFree full text

Hair-based biomarkers in women with major depressive disorder: Glucocorticoids, endocannabinoids, N-acylethanolamines, and testosterone.

Alexander Behnke, Anja M. Gumpp, Aniko Krumbholz, Alexandra M. Bach, Gustav Schelling, Iris-Tatjana Kolassa +1 more

Background Stress-related alterations in the regulation of several endocrine systems, including the hypothalamus-pituitary-adrenal (HPA) and -gonadal (HPG) axes and the endocannabinoid system are proposed to be involved in the etiology of major depressive disorder (MDD). Therefore, this study examines whether altered concentrations of glucocorticoids, testosterone, endocannabinoids, and related N-acylethanolamines…

Comprehensive Psychoneuroendocrinology