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Research Article 2025CC BYFree full text

A preliminary randomized trial of the safety, tolerability, and clinical effects of hemp-derived cannabidiol in alcohol use disorder.

Raeghan L Mueller, Jake F Hooper, Jarrod M Ellingson, Aviva K Olsavsky, Rachael Rzasa-Lynn, Angela D Bryan +2 more

Introduction Cannabidiol (CBD) has recently gained attention for its potential therapeutic effects in substance use disorders, including Alcohol Use Disorder (AUD). This study examined the potential therapeutic effects of commercially available products containing CBD with and without a small amount of tetrahydrocannabinol (THC) on alcohol use and craving among individuals with moderate to severe AUD. Methods In t…

Frontiers in Psychiatry Europe PMC

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Brief Report 2020CC BYFree full text

Investigating Relationships Between Alcohol and Cannabis Use in an Online Survey of Cannabis Users: A Focus on Cannabinoid Content and Cannabis for Medical Purposes.

Hollis C Karoly, Raeghan L Mueller, Chrysta C Andrade, Kent E Hutchison

Cannabis is commonly used among people who drink alcohol, but findings are mixed regarding the direction of this relationship. The type of cannabis used [high-cannabidiol (CBD) vs. high-delta-9tetrahydrocannabinol (THC)] and motives for use (i.e., whether cannabis is used to treat a medical condition) may influence the relationship between cannabis and drinking. Specifically, CBD has shown preclinical promise in r…

Frontiers in Psychiatry Europe PMC

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