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Browse normalized, publication-ready research with direct links to its evidence and source.
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Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
Loading articles data…
Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
3 articles
Newest firstBackground and objectives Cannabis consumption is increasing in both the recreational and medical settings. Tetrahydrocannabinol (THC) is known to produce cardiovascular effects, but the specific roles of THC and its metabolites THC-OH and THC-COOH in cannabinoid-induced cardiovascular effects remain unclear. We hypothesized that THC and THC-OH mediate a cannabinoid-induced increase in heart rate in either an addi…
Open article record in new tab ↗Introduction This prospective, single-blind, placebo-controlled trial examined the effects of intravenous delta-9-tetrahydrocannabinol (d9-THC) on the pupillary light reflex and pupil size in volunteers not regularly consuming cannabis. Methods With ethics committee approval and written informed consent, healthy cannabis-naïve or abstinent volunteers were included. Fifteen volunteers received an intravenous bolus…
Open article record in new tab ↗Background Cannabis is increasingly used and debates about the legalisation of the recreational use of cannabis are ongoing. In this prospective, placebo-controlled study in healthy volunteers not regularly consuming cannabis, subjective psychotropic and somatic effects after a single dose of intravenous THC were assessed and quantified over 48 h. Methods Twenty-five healthy volunteers received a single IV bolus o…