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Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
Loading articles data…
Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
3 articles
Newest firstIntroduction Pain constitutes the chief complaint of some functional gastrointestinal disorders (FGIDs). The endocannabinoid (EC) and peroxisome proliferator-activated receptors (PPARs) agonist systems have not been explored as possible contributors. Objective To determine if EC and PPAR agonist abnormalities occur in adolescents with FGID. Methods Institutional Review Board approved study compared 33 children (12…
Open article record in new tab ↗Abstract Rationale : Endocannabinoid signaling during adolescence plays a critical role in brain development and shapes both healthy and maladaptive behaviors, influencing the risk of neuropsychiatric disorders in adulthood. Objectives : The present study examines the effects of disrupted catabolism of the endocannabinoids 2-arachidonylglycerol (2-AG) and N -arachidonoylethanolamine (AEA) during early adolescence…
Open article record in new tab ↗Painful peripheral neuropathy is the most common neurological complication associated with human immune deficiency virus (HIV) infection. Currently available treatments fail to provide adequate symptom relief, indicating the need for novel treatment strategies. To address this gap in knowledge, we characterized the impact of cannabinoid CB2 agonists, which lack psychoactivity associated with central CB1 activation…
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