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Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
Loading articles data…
Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
5 articles
Newest firstIntroduction Satellite DNA (satDNA) is a rapidly evolving component of plant genomes, typically found in (peri)centromeric, (sub)telomeric, and other heterochromatic regions. Due to their variability and species- or population-specific distribution, satDNA serves as valuable cytogenetic markers for studying chromosomal rearrangements and karyotype evolution among closely related species. Previous studies have iden…
Open article record in new tab ↗We report the presence of the emerging plant pathogen 'Xanthomonas cannabis' in Australia through a comprehensive analysis of five historical isolates and all publicly available genomes of the species. Using comparative genomics, we characterized four isolates collected from Zinnia spp. and one from Cucurbita pepo. Our findings show that the Zinnia isolates form a distinct phylogroup with the pathotype strain of '…
Candida auris emerged in Chicago, IL, USA in 2016 and has since become endemic. We used whole genome sequencing (WGS) of 494 isolates, epidemiologic metadata, and patient transfer data to describe the transmission of C. auris among Chicago healthcare facilities between 2016 - 2021. 99% of isolates formed a single clade IV phylogenetic lineage, suggesting a single introduction. Isolates were grouped into genomic cl…
BackgroundMost seasonally circulating enteroviruses result in asymptomatic or mildly symptomatic infections. In rare cases, however, infection with some subtypes can result in paralysis or death. Of the 300 subtypes known, only poliovirus is reportable, limiting our understanding of the distribution of other enteroviruses that can cause clinical disease. ObjectiveThe overarching objectives of this study were to: 1…
Exchange proteins directly activated by cAMP (EPAC1 and EPAC2) are one of the several families of cellular effectors of the prototypical second messenger cAMP. To understand the origin and molecular evolution of EPAC proteins, we performed a comprehensive phylogenetic analysis of EPAC1 and EPAC2. Our study demonstrates that unlike its cousin PKA, EPAC proteins are only present in multicellular Metazoa. Within the…
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