Readable research linked to original sources
Articles
Browse normalized, publication-ready research with direct links to its evidence and source.
Loading articles data…
Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
Loading articles data…
Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
3 articles
Newest firstThymoquinone (TQ), the bioactive compound found in black seed, possesses beneficial properties. In the present study, the effects of oral administration of TQ were investigated on acute corneal and orofacial pains in rats. To clarify the central mechanism of action, muscarinic cholinergic, cannabinergic 1 (CB1) and 5-hydroxytryptamine receptor antagonists were delivered into the 4th ventricle of the brain after or…
Open article record in new tab ↗Cannabinoid hyperemesis syndrome (CHS) is a serious condition primarily seen in chronic cannabis users, characterized by persistent cycles of severe nausea and vomiting, often leading to frequent emergency room visits. Accurate diagnosis is crucial due to the overlap with other gastrointestinal disorders. The traditional use of antiemetics such as ondansetron often fails to alleviate symptoms, making CHS difficult…
Open article record in new tab ↗The present study examined the potential antinociceptive activity of C18 5-HT (βN-octadecanoyl-5-hydroxytryptamide) using chemical and thermal nociception models in mice. Orally administered C18 5-HT (0.1, 1 and 10 mg/kg) produced significant dose-dependent antinociceptive effects in formalin-, capsaicin- and glutamate-induced licking models. This compound also induced a significant increase in the response to the…
Open article record in new tab ↗