Culture medium and plant growth regulator regimes influence the transcriptome and cannabisin accumulation in Cannabis sativa cell suspension cultures

Margaux Thiry, Kjell Sergeant, Sylvain Legay, Marcus Iken, Jenny Renaut, Stanley Lutts +1 more

Plant cell suspension cultures are a valuable biotechnological platform for the controlled production of high-value phytochemicals. Yet, the molecular mechanisms by which culture medium composition impacts cellular transcriptional programs remain poorly characterised, especially in non-model plant species. Here, we investigated how two culture media, Murashige & Skoog (MS)- and Linsmaier & Skoog (LS)-based, influe…