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Editorial 2023CC BYFree full text

Editorial: Toxicological profiles and pharmacological properties of synthetic cannabinoids: From chemical and analytical issues to fatal and non-fatal intoxications.

Arianna Giorgetti, Rossana Cecchi, Volker Auwärter

Frontiers in Psychiatry Europe PMC

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Research Article 2022CC BYFree full text

Induction of Liver Size Reduction in Zebrafish Larvae by the Emerging Synthetic Cannabinoid 4F-MDMB-BINACA and Its Impact on Drug Metabolism.

Yu Mi Park, Charlotte Dahlem, Markus R Meyer, Alexandra K Kiemer, Rolf Müller, Jennifer Herrmann +1 more

Zebrafish (ZF; Danio rerio) larvae have become a popular in vivo model in drug metabolism studies. Here, we investigated the metabolism of methyl 2-[1-(4-fluorobutyl)-1H-indazole-3-carboxamido]-3,3-dimethylbutanoate (4F-MDMB-BINACA) in ZF larvae after direct administration of the cannabinoid via microinjection, and we visualized the spatial distributions of the parent compound and its metabolites by mass spectrome…

Molecules

Research Article 2020CC BYFree full text

Comprehensive Protocol for the Identification and Characterization of New Psychoactive Substances in the Service of Law Enforcement Agencies.

Ewa Bulska, Robert Bachliński, Michał K Cyrański, Magdalena Michalska-Kacymirow, Wioletta Kośnik, Paweł Małecki +2 more

A non-routine, comprehensive protocol for characterization of emerging new psychoactive substances (NPS) including chemical structures, impurities, as well as crystal structures, has been developed to facilitate the work of law enforcement agencies. A set of NPS has been synthesized, identified, and characterized by various analytical methods in order to be used as certified reference standards (CRMs). Seven selec…

Frontiers in Chemistry Europe PMC