Development and validation of a low-cost spectrophotometric method for cannabidiol (CBD) quantification based on the Beam reaction.

Fresia Melina Silva Sofras, Martín Federico Desimone, Sofia Municoy

Cannabidiol (CBD) is a compound of high pharmacological interest, requiring accessible analytical methods for its identification and measurement. This study proposes the transformation of the classic Beam reaction, traditionally a qualitative colorimetric test, into a robust, low-cost quantitative technique using UV-Vis spectrophotometry. The method is based on the formation of a specific chromophore between CBD/C…