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Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
Loading articles data…
Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
8 articles
Newest firstBackground & objectives Alzheimer's disease (AD) is characterized by gradual cognitive decline. Here, we deciphered the molecular mechanisms using transcriptomic data derived from the dorsolateral prefrontal cortex (DLPFC) of patients with severe AD using next-generation knowledge discovery (NGKD) techniques. Methodology RNA sequencing data from the Gene Expression Omnibus (GEO) database (GSE53697) derived from th…
Open article record in new tab ↗Objective Open Common Bile Duct Exploration (OCBDE) is a critical intervention for managing complex common bile duct (CBD) stones when endoscopic retrograde-cholangiopancreatography (ERCP) is unsuccessful. The choice of technique for choledochal exploration remains debated due to variable recurrence rates and complications associated with different methods. This study evaluates the clinical outcomes: bile leakage,…
Open article record in new tab ↗Objectives To find out the management outcomes of iatrogenic bile duct injuries following laparoscopic cholecystectomy. Methodology In this descriptive case series study total of 90 patients of both gender and who sustained extra hepatic biliary injuries, were included. Patients managed through ERCP and stenting and those with hepatobiliary malignancy were excluded. These 90 cases included those patients who susta…
Open article record in new tab ↗Objective To evaluate whether the efficacy and safety of primary duct closure(PDC) was limited to patients with a wider common bile duct(CBD) (≥8 mm). Methods A retrospective study of patients who underwent PDC after laparoscopic common bile duct exploration (LCBDE) at Taicang Affiliated Hospital of Soochow University from March 2012 to June 2019 was performed. Fifty-five patients were enrolled and classified into…
Open article record in new tab ↗Objective To evaluate the diagnostic accuracy of different imaging modalities in patients with partial biliary obstruction with no obvious aetiology on initial imaging. Methods This is a prospective single-centre cohort study carried out at Pak Emirates Military Hospital, Rawalpindi from June 2019 to June 2021 with non-probability consecutive sampling. Patients with ages 16 to 75 years, presenting with partial bil…
Open article record in new tab ↗Objective To determine accuracy of SAGES, ASGE and ESGE criteria for predicting presence of common bile duct (CBD) stones. Methods In a prospective study at Jinnah Hospital Lahore from March 2021 to February 2022, patients with suspected CBD stone were stratified in High risk (HR), intermediate risk (IR) and low risk (LR) for SAGES, ASGE and ESGE criteria. All patients underwent ERCP and risk strata were analyzed…
Open article record in new tab ↗Objective To compare the short-term outcomes of three dimensional (3D) versus two dimensional (2D) laparoscopic procedures used for cholecystectomy. Methods This study was conducted at minimally invasive surgery center of Liaquat University of Medical Health and Sciences (LUMHS) Jamshoro Pakistan, between 15th May 2017 to 16th December 2017 after taking informed consent. All patients were diagnosed cases of cholel…
Open article record in new tab ↗Objectives This study reports the indications and outcome of various biliary bypass surgical procedures from a single centre over a period of 10 years. Methods This is a prospective observational study conducted over a period of 10 years (January 2001-december 2010). A total of 1500 patients were included, who underwent pancreatico-biliary surgery due to common bile duct (CBD) stones, congenital anomalies of bilia…