Readable research linked to original sources

Articles

Browse normalized, publication-ready research with direct links to its evidence and source.

2 articles

Newest first

Research Article 2023CC BYFree full text

Deletion of Cryab increases the vulnerability of mice to the addiction-like effects of the cannabinoid JWH-018 via upregulation of striatal NF-κB expression.

Leandro Val Sayson, Darlene Mae Ortiz, Hyun Jun Lee, Mikyung Kim, Raly James Perez Custodio, Jaesuk Yun +5 more

Synthetic cannabinoids have exhibited unpredictable abuse liabilities, especially self-administration (SA) responses in normal rodent models, despite seemingly inducing addiction-like effects in humans. Thus, an efficient pre-clinical model must be developed to determine cannabinoid abuse potential in animals and describe the mechanism that may mediate cannabinoid sensitivity. The Cryab knockout (KO) mice were rec…

Frontiers in Pharmacology Europe PMC

Open article record in new tab ↗

Other 2018CC BYFree full text

1H-NMR and 13C-NMR dataset for some oxidative metabolites of CRA13 and their analogs.

Ahmed HE Hassan, Min Chang Cho, Hye In Kim, Ji Seul Yang, Kyung Tae Park, Yong Sup Lee

CRA13 (CB-13; SAB-378) is a dual CB1R/CB2R agonist cannabinoid agent developed by Novartis Pharma. Upon administration, it undergoes metabolism to oxidative metabolites. Herein, the 1H-NMR and 13C-NMR dataset of some oxidative metabolites and analogs thereof are presented for further analysis and comparison purposes, for whom may be interested.

Data in Brief Europe PMC

Open article record in new tab ↗