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Review Article 2025CC BYFree full text

The impact of using cannabis during pregnancy on the infant and mother: An overview of systematic reviews, evidence map, targeted updates, and de novo synthesis.

Zachary Munn, Danielle Pollock, Jennifer Stone, Sabira Hasanoff, Andrea Gordon, Carrie Price +2 more

Background Cannabis use during pregnancy is becoming more prevalent. While numerous studies have explored the relationship of cannabis use during pregnancy and outcomes for mothers and infants, uncertainty remains regarding the impact of cannabis use on pregnancy complications and later-life outcomes for offspring. Aims To produce a summary of the short and long-term effects of prenatal cannabis exposure on fetal…

The Australian & New Zealand Journal of Obstetrics & Gynaecology Europe PMC

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Research Article 2025-01-06CC BYFree full text

Assessing the feasibility and impact of clinical trial trustworthiness checks via an application to Cochrane Reviews: Stage 2 of the INSPECT-SR project

Jack Wilkinson, Calvin Heal, Georgios A Antoniou, Ella Flemyng, Love Ahnström, Alessandra Alteri +60 more

BackgroundThe aim of the INSPECT-SR project is to develop a tool to identify problematic RCTs in systematic reviews. In Stage 1 of the project, a list of potential trustworthiness checks was created. The checks on this list must be evaluated to determine which should be included in the INSPECT-SR tool. MethodsWe attempted to apply 72 trustworthiness checks to RCTs in 50 Cochrane Reviews. For each, we recorded whet…

medRxiv medRxiv

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