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19172026

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Author: Sreeraj Gopi

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Research Article 2018CC BYCC BY allows this article to remain publicly readable here. Any reuse must still follow the recorded source terms.Free full text

Development of Validated Methods and Quantification of Curcuminoids and Curcumin Metabolites and Their Pharmacokinetic Study of Oral Administration of Complete Natural Turmeric Formulation (Cureit™) in Human Plasma via UPLC/ESI-Q-TOF-MS Spectrometry.

Shintu Jude, Augustine Amalraj, Ajaikumar B Kunnumakkara, Chandradhara Divya, Bernd-Michael Löffler, Sreeraj Gopi

Specific and sensitive ultra-high performance liquid chromatography-quadrupole time of flight-mass spectroscopy (UPLC-QTOF-MS) methods have been developed for the determination of curcuminoids and curcumin metabolites in human blood plasma. The UPLC-QTOF-MS method used a binary solvent delivery system and the chromatographic separation was performed on a C-18 (2.1 × 50 mm; 1.7 µm) column. Mass spectra were obtaine…

Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry Europe PMC↗

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